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CAS:74495-69-5|Guaiacol-d3，2-Methoxyphenol-d3
作者：德尔塔生物 日期：2025-06-10
生物活性：Guaiacol-d3 is the deuterium labeled Guaiacol. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Guaiacol has an anti-inflammatory activity[1].分子量：127.16Formula：C7H5D3O2CAS 号：74495-69-5非标记 CAS：90-05-1性状：液体（密度：1.137 g/cm3）颜色：Light yellow to light brown中文名称：愈创木酚-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Pure form-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:185056-83-1|Coumarin-d4，香豆素 d4
作者：德尔塔生物 日期：2025-06-10
生物活性：Coumarin-d4 is the deuterium labeled Coumarin. Coumarin is the primary bioactive ingredient in Radix Glehniae, named Beishashen in China, which possesses many pharmacological activities, including anticancer, anti-inflammation and antivirus activities.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Coumarin-d4 相关抗体:Poliovirus Receptor Antibody (YA2556)分子量：150.17Formula：C9H2D4O2CAS 号：185056-83-1非标记 CAS：91-64-5性状：固体颜色：White to off-white中文名称：香豆素 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1092942-82-9|Imatinib-d8，STI571-d8; CGP-57148B-d8
作者：德尔塔生物 日期：2025-06-10
生物活性：Imatinib-d8 is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2].分子量：501.65Formula：C29H23D8N7OCAS 号：1092942-82-9非标记 CAS：152459-95-5性状：固体颜色：White to light yellow中文名称：伊马替尼 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1242184-43-5|Oseltamivir acid-d3，GS 4071-d3; Ro 64-0802-d3; Oseltamivir carboxylate-d3
作者：德尔塔生物 日期：2025-06-10
生物活性：Oseltamivir acid-d3 is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].分子量：287.37Formula：C14H21D3N2O4CAS 号：1242184-43-5非标记 CAS：187227-45-8性状：固体颜色：White to off-white中文名称：奥斯他伟酸 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1132093-70-9|Dasatinib-d8，BMS-354825-d8
作者：德尔塔生物 日期：2025-06-10
生物活性：Dasatinib-d8 is a deuterium labeled Dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.分子量：496.05Formula：C22H18D8ClN7O2SCAS 号：1132093-70-9非标记 CAS：302962-49-8性状：固体颜色：White to off-white中文名称：达沙替尼 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Sitagliptin-d4 hydrochloride
作者：德尔塔生物 日期：2025-06-10
生物活性：Sitagliptin-d4 (hydrochloride) is the deuterium labeled Sitagliptin[1]. Sitagliptin (MK-0431) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Sitagliptin-d4 hydrochloride 相关抗体:DPP4/CD26 Antibody (YA1274)分子量：447.80Formula：C16H12D4ClF6N5O非标记 CAS：486460-32-6性状：固体颜色：White to off-white中文名称：西格列汀-d4；西他列汀-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度： 99.22%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Thomas, L., et al. (R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a novel xanthine-based dipeptidyl peptidase 4 inhibitor, has a superior potency and longer duration of action compared with other dipeptidyl peptidase-4 inhibitors. J Pharmacol Exp Ther. 2008 Apr;325(1):175-82. [Content Brief][3]. Kim, S.J., et al., Dipeptid
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「同位素标记抑制剂」Oclacitinib-13C-d3
作者：德尔塔生物 日期：2025-06-10
生物活性：Oclacitinib-13C-d3 is the deuterium and 13C labeled Oclacitinib[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：341.45Formula：C1413CH20D3N5O2S非标记 CAS：1208319-26-9性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Dacomitinib-d10 dihydrochloride
作者：德尔塔生物 日期：2025-06-10
生物活性：Dacomitinib-d10 (dihydrochloride) is the deuterium labeled Dacomitinib dihydrochloride. Dacomitinib (PF-00299804) dihydrochloride is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：552.92Formula：C24H17D10Cl3FN5O2非标记 CAS：1110813-31-4性状：固体颜色：White to off-white中文名称：达克替尼 d10 (双盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)纯度 & 产品资料纯度： ≥95.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Engelman JA, et al. PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to ZD1839. Cancer Res. 2007 Dec 15;67(24):11924-32. [Content Brief][3]. Kalous O, et al. Dacomitinib (PF-00299804), an irreversible Pan-HER inhibitor, inhibits proliferation of HER2-amplified breast cancer cell lines resistant to Anti-Hu
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「同位素标记抑制剂」Doxapram-d5 hydrochloride
作者：德尔塔生物 日期：2025-06-10
生物活性：Doxapram-d5 (hydrochloride) is deuterium labeled Doxapram (hydrochloride).体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：420.00Formula：C24H26D5ClN2O2非标记 CAS：113-07-5性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度： ≥99.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」DL-Methyldopa-d3
作者：德尔塔生物 日期：2025-06-10
生物活性：DL-Methyldopa-d3 is deuterium labeled DL-Methyldopa.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：214.23Formula：C10H10D3NO4非标记 CAS：55-40-3性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： 98.17%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」Entinostat-d4
作者：德尔塔生物 日期：2025-06-10
生物活性：Entinostat-d4 is the deuterium labeled Entinostat[1]. Entinostat is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Entinostat-d4 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyHDAC1 AntibodyHDAC6 Antibodyc-Myc AntibodyCyclin E1 AntibodyHDAC4 Antibody (YA741)SATB2 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)分子量：380.43Formula：C21H16D4N4O3非标记 CAS：209783-80-2性状：固体颜色：White to off-white中文名称：恩替诺特-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： 90.31%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics
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「同位素标记抑制剂」Vinorelbine-d3 ditartrate
作者：德尔塔生物 日期：2025-06-10
生物活性：Vinorelbine-d3 (ditartrate) is the deuterium labeled Vinorelbine ditartrate. Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Vinorelbine-d3 ditartrate 相关抗体:alpha Tubulin AntibodyLC3A/B AntibodyBeta Tubulin Antibodybeta Tubulin Antibody (YA839)Doublecortin AntibodyLC3B Antibody (YA308)Stathmin 1 Antibody (YA049)Stathmin 1 Antibody (YA050)alpha Tubulin (acetyl K40) Antibodybeta III Tubulin Antibodygamma Tubulin AntibodyLC3B AntibodyBeta Tubulin Antibody (HRP) (YA865)Cytokeratin 5 AntibodyMAP2 AntibodyDM1 Antibody (YA898)CK18 AntibodyCytokeratin 19 AntibodyCytokeratin 7 Antibody (YA951)Cytokeratin 15 Antibody (YA1493)p63 Antibody (YA1531)Cytokeratin 6 Antibody (YA1701)Cytokeratin 4 Antibody (YA1762)Cytokeratin 10 Antibody (YA1857)Cytokeratin 14 Antibody (YA1876)Cytokeratin 1 Antibody (YA2665)Stanniocalcin 1 Antibody (YA2690)Cytokeratin 13 Antibody (YA2695)HRH3 Antibody (YA2701)Phospho-alpha Tubulin (Tyr272) Antibody (YA3041)分子量：1082.12Formula：C53H63D3N4O20非标记 CAS：125317-39-7性状：固体颜色：White to off-white中文名称：酒石酸长春瑞滨 d3 (双酒石酸盐)运输条件：Shipping with
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「同位素标记抑制剂」1,2-Dioleoyl-sn-glycero-3-phosphocholine-d9
作者：德尔塔生物 日期：2025-06-10
生物活性：1,2-Dioleoyl-sn-glycero-3-phosphocholine-d9 is deuterium labeled 1,2-Dioleoyl-sn-glycero-3-phosphocholine. 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelle体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.1,2-Dioleoyl-sn-glycero-3-phosphocholine-d9 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：795.17Formula：C44H75D9NO8P非标记 CAS：4235-95-4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sh
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「同位素标记抑制剂」cis-Urocanic acid-13C3
作者：德尔塔生物 日期：2025-06-10
生物活性：cis-Urocanic acid-13C3 is the 13C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.cis-Urocanic acid-13C3 相关抗体:MTNR1A Antibody分子量：139.09Formula：C313C3H4N2O2非标记 CAS：7699-35-6性状：固体颜色：White to off-white中文名称：顺式-尿刊酸 13C3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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「同位素标记抑制剂」DPPC-d9
作者：德尔塔生物 日期：2025-06-10
生物活性：DPPC-d9 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers[1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.DPPC-d9 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：743.09Formula：C40H71D9NO8P非标记 CAS：63-89-8性状：固体颜色：White to off-white中文名称：二棕榈酰磷脂酰胆碱 d9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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