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「同位素标记抑制剂」Tedizolid-13C,d3

「同位素标记抑制剂」Tedizolid-13C,d3

作者:德尔塔生物 日期:2025-06-11

生物活性:Tedizolid-13C,d3 is the 13C- and deuterium labeled Tedizolid. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[54].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Tedizolid-13C,d3 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量:374.35Formula:C1613CH12D3FN6O3CAS 号:2931763-72-1非标记 CAS:856866-72-3中文名称:特地唑胺-13C,d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokine

「同位素标记抑制剂」Fmoc-L-Lys (Boc)-OH-13C6,15N2

「同位素标记抑制剂」Fmoc-L-Lys (Boc)-OH-13C6,15N2

作者:德尔塔生物 日期:2025-06-11

生物活性:Fmoc-L-Lys (Boc)-OH-13C6,15N2 is a 15N-labeled and 13C-labled Triclabendazole.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fmoc-L-Lys (Boc)-OH-13C6,15N2 相关抗体:alpha Tubulin AntibodyLC3A/B AntibodyBeta Tubulin Antibodybeta Tubulin Antibody (YA839)Doublecortin AntibodyLC3B Antibody (YA308)Stathmin 1 Antibody (YA049)Stathmin 1 Antibody (YA050)alpha Tubulin (acetyl K40) Antibodybeta III Tubulin Antibodygamma Tubulin AntibodyLC3B AntibodyBeta Tubulin Antibody (HRP) (YA865)Cytokeratin 5 AntibodyMAP2 AntibodyDM1 Antibody (YA898)CK18 AntibodyCytokeratin 19 AntibodyCytokeratin 7 Antibody (YA951)Cytokeratin 15 Antibody (YA1493)p63 Antibody (YA1531)Cytokeratin 6 Antibody (YA1701)Cytokeratin 4 Antibody (YA1762)Cytokeratin 10 Antibody (YA1857)Cytokeratin 14 Antibody (YA1876)Cytokeratin 1 Antibody (YA2665)Stanniocalcin 1 Antibody (YA2690)Cytokeratin 13 Antibody (YA2695)HRH3 Antibody (YA2701)Phospho-alpha Tubulin (Tyr272) Antibody (YA3041)分子量:476.48Formula:C2013C6H3215N2O6CAS 号:850080-89-6非标记 CAS:71989-26-9运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet

「同位素标记抑制剂」Etoperidone-d8 hydrochloride

「同位素标记抑制剂」Etoperidone-d8 hydrochloride

作者:德尔塔生物 日期:2025-06-11

生物活性:Etoperidone-d8 (hydrochloride) is the deuterium labeled Etoperidone hydrochloride[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:422.42Formula:C19H21D8Cl2N5OCAS 号:1329796-60-2非标记 CAS:57775-22-1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

「同位素标记抑制剂」Flunixin-d3

「同位素标记抑制剂」Flunixin-d3

作者:德尔塔生物 日期:2025-06-11

生物活性:Flunixin-d3 is the deuterium labeled Flunixin. Flunixin Meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Flunixin-d3 相关抗体:COX2 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCOX IV Antibody (YA867)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)分子量:299.26Formula:C14H8D3F3N2O2CAS 号:1015856-60-6非标记 CAS:38677-85-9中文名称:氟尼克辛-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Cox L, et al. Levomepromazine for nausea and vomiting in palliative care. Cochrane Database Syst Rev. 2015;2015(11):CD009420. Published 2015 Nov 2. [Content Brief][2]. Cheng Z, et al. Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. Inflammation. 1998 Aug;22(4):353-66. [Content Brief][3]. Bryant, C.E., B.A. Farnfield, and H.J. Janicke, Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nu

「同位素标记抑制剂」1'-Hydroxymidazolam-13C3

「同位素标记抑制剂」1'-Hydroxymidazolam-13C3

作者:德尔塔生物 日期:2025-06-11

生物活性:1'-Hydroxymidazolam-13C3 is the 13C labeled 1'-Hydroxymidazolam[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.1'-Hydroxymidazolam-13C3 相关抗体:FMO3 Antibody (YA1992)分子量:344.74Formula:C1513C3H13ClFN3OCAS 号:1189677-14-2非标记 CAS:59468-90-5中文名称:咪达唑仑杂质1-13C3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

「同位素标记抑制剂」Tianeptine-d12

「同位素标记抑制剂」Tianeptine-d12

作者:德尔塔生物 日期:2025-06-11

生物活性:Tianeptine-d12 is a deuterated analog of Tianeptine. Tianeptine is an antidepressant with oral activity and neurochemical properties. Tianeptine has neuroprotective effects against hypoxia in tissue culture and against the deleterious effects of cytokines in the cortex and white matter, but not against NMDA receptor-mediated excitotoxicity[1][2][3][4].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:449.03Formula:C21H13D12ClN2O4SCAS 号:1189870-26-5非标记 CAS:72797-41-2中文名称:噻奈普汀 d12运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Wagstaff A J, et al. Tianeptine: a review of its use in depressive disorders[J]. CNS drugs, 2001, 15: 231-259.[3]. Plaisant F, et al. Neuroprotective properties of tianeptine: interactions with cytokines[J]. Neuropharmacology, 2003, 44(6): 801-809. [Content Brief][4]. Sharma A K, et al. Effects of calcium channel blocker,

「同位素标记抑制剂」Palonosetron-d3 hydrochloride

「同位素标记抑制剂」Palonosetron-d3 hydrochloride

作者:德尔塔生物 日期:2025-06-11

生物活性:Palonosetron-d3 (hydrochloride) is the deuterium labeled Palonosetron hydrochloride. Palonosetron hydrochloride is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV)[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Palonosetron-d3 hydrochloride 相关抗体:MTNR1A Antibody分子量:335.89Formula:C19H22D3ClN2OCAS 号:1246816-81-8非标记 CAS:135729-62-3中文名称:盐酸帕洛诺司琼 d3 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (559 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Vishnu Murthy M, Srinivas K, Kumar R, Mukkanti K.Development and validation of a stability-indicating LC method for determining palonosetron hydrochloride, its related compounds and degradation products using naphthalethyl stationary phase.J Pharm Biomed Anal. 2011 Sep 10;56(2):429-35. [Content Brief][3]. Ajioka H, Morita F, Akizawa Y, Yoshida K, Kitamura R, Takimoto H.Pharmacolog

「同位素标记抑制剂」Perindopril-d4 erbumine

「同位素标记抑制剂」Perindopril-d4 erbumine

作者:德尔塔生物 日期:2025-06-11

生物活性:Perindopril-d4 t-butylamine salt is the deuterium labeled Perindopril t-butylamine salt. Perindopril t-butylamine salt is a long-acting ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Perindopril-d4 erbumine 相关抗体:ACE2 AntibodyACE AntibodyACE Antibody (YA2094)分子量:445.63Formula:C23H39D4N3O5CAS 号:1356929-59-3非标记 CAS:107133-36-8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Vaclavik J, Perindopril in the treatment of hypertension and cardiovascular diseases: evolution continues with the orodispersible dosage form. Vnitr Lek. 2013 Apr;59(4):290-4. [Content Brief][3]. Napalkov DA. Therapy with perindopril: organoprotection, not just the antihypertensive effect. Kardiologiia. 2012;52(12):80-3. [Content Brief]

「同位素标记抑制剂」rac cis-Moxifloxacin-d4 hydrochloride

「同位素标记抑制剂」rac cis-Moxifloxacin-d4 hydrochloride

作者:德尔塔生物 日期:2025-06-11

生物活性:rac cis-Moxifloxacin-d4 (hydrochloride) is the deuterium labeled Moxifloxacin hydrochloride. Moxifloxacin Hydrochloride (BAY 12-8039) is an oral 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia[1][2].IC50 & Target:Quinolone体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.rac cis-Moxifloxacin-d4 hydrochloride 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量:441.92Formula:C21H21D4ClFN3O4CAS 号:1217802-65-7非标记 CAS:186826-86-8性状:固体颜色:White to light yellow中文名称:盐酸莫西沙星 d4 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Store at room temperature, keep dry and coolIn solvent:-80°C:2 years-2

「同位素标记抑制剂」Vedaprofen-d3

「同位素标记抑制剂」Vedaprofen-d3

作者:德尔塔生物 日期:2025-06-11

生物活性:Vedaprofen-d3 is the deuterium labeled Vedaprofen. Vedaprofen (Quadrisol) is a COX-1 selective nonsteroidal anti-inflammatory agent (NSAID) for serum TxB2 and exudate PGE2 inhibition [1]. Vedaprofen is a Escherichia coli (E. coli) sliding clamp (SC) inhibitor with the IC50 of 222 μM[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Vedaprofen-d3 相关抗体:COX2 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCOX IV Antibody (YA867)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)分子量:285.40Formula:C19H19D3O2CAS 号:1185054-34-5非标记 CAS:71109-09-6中文名称:维达洛芬-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief][2]. P Lees, et al. PK-PD integration and PK-PD modelling of nonsteroidal anti-inflammatory drugs: principles and applications in veterinary pharmacology. J Vet Pharmacol Ther. 2004 Dec;27(6):491-502. [Content Brief][3]. Zhou Yin

CAS:1219805-09-0|Ibuprofen-d3 sodium,布洛芬钠盐-d3; (±-Ibuprofen-d3 sodium

CAS:1219805-09-0|Ibuprofen-d3 sodium,布洛芬钠盐-d3; (±-Ibuprofen-d3 sodium

作者:德尔塔生物 日期:2025-06-10

生物活性:Ibuprofen-d3 ((±)-Ibuprofen-d3) sodium is the deuterium labeled Ibuprofen sodium (HY-78131C). Ibuprofen sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers[1][2][3][4].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ibuprofen-d3 sodium 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量:231.28Formula:C13H14D3NaO2CAS 号:1219805-09-0非标记 CAS:31121-93-4性状:固体颜色:White to off-white中文名称:布洛芬钠盐-d3; 异丁洛芬钠盐-d3;异丁苯丙酸钠盐-d3运输条件:Room temperature in continental US; may vary

CAS:2673270-36-3|Amoxicillin-d4,Amoxycillin d4

CAS:2673270-36-3|Amoxicillin-d4,Amoxycillin d4

作者:德尔塔生物 日期:2025-06-10

生物活性:Amoxicillin-d4 is a deuterium labeled Amoxicillin. Amoxicillin is an antibiotic with good oral absorption and broad spectrum antimicrobial activity[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Amoxicillin-d4 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量:369.43Formula:C16H15D4N3O5SCAS 号:2673270-36-3非标记 CAS:26787-78-0性状:固体颜色:White to off-white中文名称:阿莫西林钠 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:1189678-81-6|Salicylic acid-13C6,2-Hydroxybenzoic acid-13C6

CAS:1189678-81-6|Salicylic acid-13C6,2-Hydroxybenzoic acid-13C6

作者:德尔塔生物 日期:2025-06-10

生物活性:Salicylic acid-13C6 is the 13C-labeled Salicylic acid (HY-B0167). Salicylic acid is a precursor to and a metabolite of Aspirin.html" class="link-product" target="_blank">Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Salicylic acid-13C6 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyMETTL3 Antibodyc-Myc AntibodyCyclin E1 AntibodyTSG101 AntibodyAIF Antibody (YA636)ALIX AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)CNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 Antibody分子量:144.08Formula:C13C6H6O3CAS 号:1189678-81-6非标记 CAS:69-72-7性状:固体颜色:Off-white to light yellow中文名称:水杨酸 13C6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:1185241-19-3|Entacapone-d10,恩他卡朋 d10

CAS:1185241-19-3|Entacapone-d10,恩他卡朋 d10

作者:德尔塔生物 日期:2025-06-10

生物活性:Entacapone-d10 is the deuterium labeled Entacapone. Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 µM). Entacapone can be used for the research of Parkinson's disease[1]. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders[2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:315.35Formula:C14H5D10N3O5CAS 号:1185241-19-3非标记 CAS:130929-57-6性状:固体颜色:Yellow to brown中文名称:恩他卡朋 d10运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

CAS:1314417-95-2|Thiocolchicine-d3

CAS:1314417-95-2|Thiocolchicine-d3

作者:德尔塔生物 日期:2025-06-10

生物活性:Thiocolchicine-d3 is deuterium labeled Thiocolchicine. Thiocolchicine, a derivative modified in the C Ring of Colchicine (HY-16569) with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization (IC50=2.5 µM) and competitively binds to tubulin with a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis[1][2]. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Thiocolchicine-d3 相关抗体:ERK1/2 Antibodyalpha Tubulin AntibodyLC3A/B AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyBeta Tubulin Antibodyc-Myc AntibodyCyclin E1 Antibodybeta Tubulin Antibody (YA839)AIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)Doublecortin AntibodyDR5 AntibodyDrosha Antibody分子量:418.52Formula:C22H22D3NO5SCAS 号:1314417-95-2非标记 CAS:2730-71-4性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)