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「同位素标记抑制剂」Piribedil-d8
作者：德尔塔生物 日期：2025-09-18
生物活性：Piribedil-d8 is the deuterium labeled Piribedil, which is an antiparkinsonian agent.分子量：306.39Formula：C16H10D8N4O2CAS 号：1398044-45-5非标记 CAS：3605-01-4性状：固体颜色：White to off-white中文名称：吡贝地尔 d8；双哌嘧啶 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Gilteritinib-d8
作者：德尔塔生物 日期：2025-09-18
生物活性：Gilteritinib-d8 is deuterium labeled Gilteritinib. Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Gilteritinib-d8 相关抗体:AXL AntibodyMERTK Antibody (YA2966)分子量：560.76Formula：C29H36D8N8O3CAS 号：2377109-74-3非标记 CAS：1254053-43-4性状：固体颜色：White to yellow运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Bempedoic acid-d4
作者：德尔塔生物 日期：2025-09-18
生物活性：Bempedoic acid-d4 is the deuterium labeled Bempedoic acid. Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor. Bempedoic acid (ETC-1002) activates AMPK[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Bempedoic acid-d4 相关抗体:AMPK alpha AntibodyPhospho-AMPK alpha 2 (Thr172) AntibodyAMPK alpha 2 Antibody (YA833)Phospho-AMPK alpha 2(Ser345) AntibodyAMPK alpha 1 AntibodyAMPK alpha 1 Antibody (YA624)ATP citrate lyase AntibodyPhospho-AMPK alpha 1 (Ser496) Antibody (YA226)Phospho-Hormone sensitive lipase (Ser853) AntibodyATF4 Antibody (YA605)AMPK alpha 2 Antibody (YA623)AMPK beta 1 AntibodyAMPK gamma 1 AntibodyATF4 AntibodyATP Citrate Lyase Antibody (YA829)Phospho-AMPK alpha 1 (Ser496) AntibodyMARK2 Antibody (YA2104)MARK3 Antibody (YA2150)Phospho-Hormone Sensitive Lipase (Ser855) Antibody (YA2599)分子量：348.51Formula：C19H32D4O5CAS 号：2408131-70-2非标记 CAS：738606-46-7性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Resolvin D2-d5
作者：德尔塔生物 日期：2025-09-18
生物活性：Resolvin D2-d5 is the deuterium labeled Resolvin D2. Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 (IC50 = 0.1 nM) and TRPA1 (IC50 = 2 nM) in primary sensory neurons[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Resolvin D2-d5 相关抗体:TRPM8 Antibody (YA1609)TRPM7 Antibody (YA2391)TrpC1 Antibody (YA1814)分子量：381.52Formula：C22H27D5O5CAS 号：1881277-33-3非标记 CAS：810668-37-2性状：液体颜色：Colorless to light yellow运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Solution, -20°C, 2 years纯度 & 产品资料纯度： ≥99.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Siddiqui YD, et al. Resolvin D2 Induces Resolution of Periapical Inflammation and Promotes Healing of Periapical Lesions in Rat Periapical Periodontitis. Front Immunol. 2019 Feb 26;10:307. [Content Brief][3]. Spite M, et al. Resolvin D2 is a potent regulator of leukocytes and controls micr
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「同位素标记抑制剂」Apremilast-d5
作者：德尔塔生物 日期：2025-09-18
生物活性：Apremilast-d5 is a deuterium labeled Apremilast. Apremilast is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM[1].IC50 & Target[1]：PDE4分子量：465.53Formula：C22H19D5N2O7SCAS 号：1258597-47-5非标记 CAS：608141-41-9性状：固体颜色：Off-white to light yellow中文名称：阿普司特 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Urea-13C
作者：德尔塔生物 日期：2025-09-18
生物活性：Urea-13C is the 13C labelled urea. The Urea-13C breath test (13C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection[1].分子量：61.05Formula：13CH4N2OCAS 号：58069-82-2性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」D-Erythrose-4-13C
作者：德尔塔生物 日期：2025-09-18
生物活性：D-Erythrose-4-13C is the 13C labeled D-Erythrose[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：121.10Formula：C313CH8O4CAS 号：90913-08-9非标记 CAS：583-50-6性状：液体颜色：Colorless to light yellow运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Solution, -20°C, 2 years纯度 & 产品资料纯度： 99.18%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」11-Beta-hydroxyandrostenedione-d4
作者：德尔塔生物 日期：2025-09-18
生物活性：11-Beta-hydroxyandrostenedione-d4 is the deuterium labeled 11-Beta-hydroxyandrostenedione. 11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3,17-dione) is a steroid mainly found in the the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11β-hydroxysteroid dehydrogenase (11βHSD) isozymes inhibitor[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：306.43Formula：C19H22D4O3CAS 号：2687960-98-9非标记 CAS：382-44-5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (538 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Rachelle Gent, et al. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17αhydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol
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「同位素标记抑制剂」7α,25-Dihydroxycholesterol-d6
作者：德尔塔生物 日期：2025-09-18
生物活性：7α,25-Dihydroxycholesterol-d6 is deuterium labeled 7α,25-Dihydroxycholesterol. 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：424.69Formula：C27H40D6O3CAS 号：2260669-11-0非标记 CAS：64907-22-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Liu C, et al. Oxysterols direct B-cell migration through EBI2. Nature. 2011 Jul 27;475(7357):519-23. [Content Brief][2]. Hannedouche S, et al. Oxysterols direct immune cell migration via EBI2. Nature. 2011 Jul 27;475(7357):524-7. [Content Brief][3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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「同位素标记抑制剂」Zymostenol-d7
作者：德尔塔生物 日期：2025-09-18
生物活性：Zymostenol-d7 is deuterium labeled 5a-Cholest-8-en-3b-ol.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Zymostenol-d7 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：393.70Formula：C27H39D7OCAS 号：2260669-19-8非标记 CAS：566-97-2性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： ≥99.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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「同位素标记抑制剂」Hydrochlorothiazid-13C,d2
作者：德尔塔生物 日期：2025-09-18
生物活性：Hydrochlorothiazid-13C,d2 is the 13C- and deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[71].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Hydrochlorothiazid-13C,d2 相关抗体:Smad3 AntibodyTGF beta 1 AntibodySmad1 AntibodySmad2 AntibodySmad4 AntibodySmad5 AntibodyPhospho-Smad3 (Ser423/Ser425) AntibodyATP1A1 AntibodyCD105 Antibody (YA547)Noggin Antibody (YA698)Phospho-Smad1 (Ser463/Ser465) AntibodyPhospho-Smad2 (Ser250) AntibodyPhospho-Smad3 (Ser423/425) AntibodySmad2/3 AntibodyInhibin beta A Antibody (YA2780)Phospho-Smad5 (Ser463/465) Antibody (YA2838)LGI1 Antibody (YA2885)Inhibin alpha Antibody (YA1232)Inhibin beta B Antibody (YA1677)Cardiac Troponin C Antibody (YA2125)Phospho-NDRG1 (Ser330) Antibody (YA2618)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)Kir2.1 Antibody (YA2871)SARA Antibody (YA3226)分子量：300.74Formula：C613CH6D2ClN3O4S2C
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「同位素标记抑制剂」Allopurinol-d2
作者：德尔塔生物 日期：2025-09-18
生物活性：Allopurinol-d2 is deuterium labeled Allopurinol. Allopurinol is a potent xanthine oxidase inhibitor (IC50 values of 0.2 to 50 μM). Allopurinol can be used for the research of hyperuricemia and gout. Antileishmanial effect[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Allopurinol-d2 相关抗体:Xanthine Oxidase Antibody (YA1957)分子量：138.12Formula：C5H2D2N4OCAS 号：916979-34-5非标记 CAS：315-30-0性状：固体颜色：White to off-white中文名称：别嘌醇-d2运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Thiabendazole-d4
作者：德尔塔生物 日期：2025-09-18
生物活性：Thiabendazole-d4 is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Thiabendazole-d4 相关抗体:Parkin AntibodyMCU AntibodyMitofusin 2 AntibodyLIAS AntibodyNDUFS8 Antibody (YA1352)TOMM20 Antibody (YA1380)NUDT9 Antibody (YA1453)CPS1 Antibody (YA1661)Complex III Subunit 5 Antibody (YA1865)NDUFB8 Antibody (YA1947)MFF Antibody (YA2012)NDUFS4 Antibody (YA2072)MT ND1 Antibody (YA2089)Mitochondrial Fission 1 Protein Antibody (YA2098)Cyclophilin 40 Antibody (YA2099)TIMM44 Antibody (YA2207)NDUFS1 Antibody (YA2535)CLPX Antibody (YA2814)MTCO2 Antibody (YA3254)Mitochondrial Ferritin Antibody (YA3353)mtTFA Antibody (YA3360)Mitofusin 1 AntibodyOrnithine Carbamoyltransferase/OTC Antibody (YA1230)NDUFB10 Antibody (YA1330)NDUFB11 Antibody (YA1331)NDUFB2 Antibody (YA1335)NDUFB4 Antibody (YA1338)NDUFB9 Antibody (YA1340)NDUFC2 Antibody (YA1343)NDUFS3 Antibody (YA1346)分子量：205.27Formula：C10H3D4N3SCAS 号：1190007-20-5非标记 CAS：148-79-8性状：固体颜色：White to off-white中文名称：噻菌灵-d4； 噻苯唑-d4； 噻苯咪唑-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solve
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「同位素标记抑制剂」Sulfadimethoxine-d6
作者：德尔塔生物 日期：2025-09-18
生物活性：Sulfadimethoxine-d6 is the deuterium labeled Sulfadimethoxine. Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections[1].分子量：316.37Formula：C12H8D6N4O4SCAS 号：73068-02-7非标记 CAS：122-11-2性状：固体颜色：White to off-white中文名称：磺胺二甲氧嗪-d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Cefoperazone-d5
作者：德尔塔生物 日期：2025-09-18
生物活性：Cefoperazone-d5 is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity[1].IC50 & Target：β-lactam体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cefoperazone-d5 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：650.70Formula：C25H22D5N9O8S2CAS 号：2410425-70-4非标记 CAS：62893-19-0性状：固体颜色：White to off-white中文名称：头孢哌酮-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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