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「同位素标记抑制剂」CAS:2673270-28-3|TML-6-d3
作者:德尔塔生物 日期:2025-06-13
生物活性:TML-6-d3 is the deuterium labeled TML-6. TML-6, an orally active curcumin derivative, inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 can upregulate Apo E, suppress NF-κB and mTOR, and increase the activity of the anti-体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.TML-6-d3 相关抗体:PGK1 AntibodyNF-KB p65 AntibodyPhospho-NF-KB p65 (Ser536) AntibodyPhospho-NF-κB p65 (Ser529) AntibodyNF-KB p65 Antibody (YA267)Keap1 AntibodyPhospho-mTOR (Ser2448) Antibody (YA171)Phospho-Nrf2 (Ser40) Antibody (YA169)mTOR Antibody (YA281)NF-KB p105/p50 AntibodyRelB AntibodyRet AntibodyRetinoic Acid Receptor alpha AntibodyRHEB AntibodySOD2 Antibody (YA071)SOX1 AntibodyTRAF2 AntibodyPhospho-mTOR (Ser2448) Antibody (YA691)Phospho-Nrf2 (Ser40) Antibody (YA168)Hamartin Antibody4E BP1 AntibodyAnnexin A1 Antibody (YA832)DDX3 Antibody (YA784)mTOR AntibodyNF-KB p100 AntibodyNF-KB p105 Antibody (YA700)Nrf1 AntibodyPhospho-4E BP1 (Thr46) AntibodyPhospho-mTOR (Ser2481) AntibodyPhospho-NF-KB p65 (Thr254) Antibody分子量:526.64Formula:C30H34D3NO7CAS 号:2673270-28-3非标记 CAS:1462868-88-7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under
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「同位素标记抑制剂」CAS:2673270-14-7|Mitotane-d8
作者:德尔塔生物 日期:2025-06-13
生物活性:Mitotane-d8 is the deuterium labeled Mitotane[1]. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[2][3][4][5].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Mitotane-d8 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase Antib
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「同位素标记抑制剂」CAS:2315262-31-6|Psychosine-d7
作者:德尔塔生物 日期:2025-06-13
生物活性:Psychosine-d7 is deuterium labeled Psychosine. Psychosine, a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease. Psychosine is a highly cytotoxic lipid, capable of inducing cell death in a wide variety of cell体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Psychosine-d7 相关抗体:Phospho-PKC alpha (T638) AntibodyPhospho-PKC zeta (T560) AntibodyPKC alpha AntibodyPKC beta 1 AntibodyPKC beta 2 AntibodyPKC delta AntibodyPKC epsilon AntibodyPKC gamma AntibodyEzrin Antibody (YA767)PKC eta AntibodySGK1 Antibody (YA1525)PKC theta Antibody (YA3162)Villin AntibodyPhospho-PKC alpha (Ser657) Antibody (YA1023)Phospho-PKC alpha (Thr638) Antibody (YA1024)PRKCQ Antibody (YA1106)AMHR2 Antibody (YA1337)Phospho-PKC (Ser660) Antibody (YA1394)Phospho-PKC delta (Ser299) Antibody (YA2628)Phospho-PKC zeta/lambda (Thr410/Thr412) Antibody (YA2631)Phospho-PKC zeta (Thr560) Antibody (YA2679)分子量:468.68Formula:C24H40D7NO7CAS 号:2315262-31-6非标记 CAS:2238-90-6中文名称:鞘氨醇半乳糖苷-d7;半乳糖基鞘氨醇-d7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 &
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「同位素标记抑制剂」CAS:1219798-52-3|Terbuthylazine-desethyl-d9
作者:德尔塔生物 日期:2025-06-13
生物活性:Terbuthylazine-desethyl-d9 is the deuterium labeled Terbuthylazine-desethyl[1]. Terbuthylazine-desethyl (Desethylterbuthylazine) is a chloro dealkylated metabolite of Terbuthylazine (a triazine herbicide)[2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:210.71Formula:C7H3D9ClN5CAS 号:1219798-52-3非标记 CAS:30125-63-4中文名称:去乙基特丁津-d9运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Potter TL, et, al. Tillage, cover-crop residue management, and irrigation incorporation impact on fomesafen runoff. J Agric Food Chem. 2011 Jul 27;59(14):7910-5. [Content Brief][3]. Navarro S, et, al. Determination of simazine, terbuthylazine, and their dealkylated chlorotriazine metabolites in soil using sonication microextraction and gas chromatography. J AOAC Int. Sep-Oct 200083(5):1239-43. [Content Brief]
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「同位素标记抑制剂」CAS:1131342-85-2|Finasteride-d9
作者:德尔塔生物 日期:2025-06-13
生物活性:Finasteride-d9 is deuterium labeled Finasteride. Finasteride (MK-906) is a potent and competitive 5α-reductase inhibitor, with an IC50 of 4.2 nM for type II 5α-reductase. Finasteride has approximately a 100-fold greater affinity for type II 5α-reductase enzyme than for the type I enzyme. Finasteride can be used for the research of benign prostatic hyperplasia (BPH) and androgenic alopecia[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:381.60Formula:C23H27D9N2O2CAS 号:1131342-85-2非标记 CAS:98319-26-7性状:固体颜色:White to off-white中文名称:非那雄胺-d9;非那斯特萊-d9;非那司提-d9;非那甾胺-d9运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 99.13%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Flores E, et, al. Steroid 5alpha-reductase inhibitors. Mini Rev Med Chem. 2003 May;3(3):225-37. [Content Brief][3]. Yun DK, et, al. Finasteride Increases the Expression of Hemoxygenase-1 (HO-1) and NF-E2-Related Factor-2 (Nrf2) Proteins in PC-3 Cells: Implic
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「同位素标记抑制剂」CAS:265989-50-2|Ortho-hydroxy atorvastatin lactone-d5
作者:德尔塔生物 日期:2025-06-13
生物活性:Ortho-hydroxy atorvastatin lactone-d5 is deuterium labeled 2-Hydroxy atorvastatin lactone. 2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ortho-hydroxy atorvastatin lactone-d5 相关抗体:FMO3 Antibody (YA1992)分子量:561.65Formula:C33H28D5FN2O5CAS 号:265989-50-2非标记 CAS:163217-74-1中文名称:正羟基阿托伐他汀内酯杂质93-d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (536 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Guo CX, et al. Effects of Ginkgo biloba extracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices. Xenobiotica. 2012;42(8):784‐790. [Content Brief][3]. Turner NA, et al. Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferatio
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「同位素标记抑制剂」CAS:1255507-88-0|Carbendazimb-d3
作者:德尔塔生物 日期:2025-06-13
生物活性:Carbendazimb-d3 is the deuterium labeled Ofloxacin. Ofloxacin (Hoe-280) is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Carbendazimb-d3 相关抗体:SDHA Antibody分子量:194.21Formula:C9H6D3N3O2CAS 号:1255507-88-0非标记 CAS:10605-21-7中文名称:多菌灵-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (523 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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「同位素标记抑制剂」CAS:1261392-69-1|Desethyl chloroquine-d5
作者:德尔塔生物 日期:2025-06-13
生物活性:Desethyl chloroquine-d5 is deuterium labeled Desethyl chloroquine. Desethyl chloroquine is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity[1][2].IC50 & Target:Plasmodium体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Desethyl chloroquine-d5 相关抗体:IRF3 AntibodyToll-Like Receptor 4 AntibodyToll-Like Receptor 3 AntibodyTLR2 AntibodyToll-Like Receptor 2 Antibody (YA1932)TRIF Antibody (YA2263)TIRAP Antibody (YA2589)Toll-Like Receptor 9 Antibody (YA3321)Toll-Like Receptor 7 Antibody (YA2514)Toll-Like Receptor 5 Antibody (YA3265)分子量:296.85Formula:C16H17D5ClN3CAS 号:1261392-69-1非标记 CAS:1476-52-4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Ajayi FO, et al. Comparison of the partitioning in vitro of chloroquine and its dese
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「同位素标记抑制剂」CAS:1854126-47-8|Cletoquine-d4
作者:德尔塔生物 日期:2025-06-13
生物活性:Cletoquine-d4 is deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment[1][2].IC50 & Target:Plasmodium体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cletoquine-d4 相关抗体:Poliovirus Receptor Antibody (YA2556)分子量:311.84Formula:C16H18D4ClN3OCAS 号:1854126-47-8非标记 CAS:4298-15-1中文名称:羟氯喹EP杂质C (Desethyl Hydroxy Chloroquine)-d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Kumar M, et al. Molecular docking studies of chloroquine and its derivatives against P23pro-zbd domain of chikungunya virus: Implica
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「同位素标记抑制剂」CAS:1346599-86-7|Blonanserin-d5
作者:德尔塔生物 日期:2025-06-13
生物活性:Blonanserin-d5 is a deuterium labeled Blonanserin. Blonanserin is a dopamine D2/5-HT2 receptor antagonist and an atypical antipsychotic[1][2].IC50 & Target[1][2]5-HT2 ReceptorD2 Receptor分子量:372.53Formula:C23H25D5FN3CAS 号:1346599-86-7非标记 CAS:132810-10-7中文名称:布南色林 d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (523 KB)产品使用指南 (1538 KB)参考文献[1]. Tenjin, T., et al., Profile of blonanserin for the treatment of schizophrenia. Neuropsychiatr Dis Treat, 2013. 9: p. 587-94. [Content Brief][2]. Oka, M., et al., Pharmacological profile of AD-5423, a novel antipsychotic with both potent dopamine-D2 and serotonin-S2 antagonist properties. J Pharmacol Exp Ther, 1993. 264(1): p. 158-65. [Content Brief]
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「同位素标记抑制剂」CAS:1346601-02-2|Itopride-d6 hydrochloride
作者:德尔塔生物 日期:2025-06-13
生物活性:Itopride-d6 (hydrochloride) is deuterium labeled Itopride (hydrochloride). Itopride hydrochloride (HSR803), a gastroprokinetic Benzamide (HY-Z0283) derivative, is an inhibitor of acetylcholinesterase (AChE) and dopamine D2 receptor[1][2].IC50 & Target:D2 Receptor体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Itopride-d6 hydrochloride 相关抗体:CHRNA9 AntibodyDRD2 AntibodyChAT AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量:400.93Formula:C20H21D6ClN2O4CAS 号:1346601-02-2非标记 CAS:122892-31-3中文名称:盐酸伊托必利-d6;依托必利盐酸盐-d6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Hyun Chul Lim, et al. Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro. Effect of Itopride
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「同位素标记抑制剂」CAS:1089675-56-8|Phenylephrine-d6 hydrochloride
作者:德尔塔生物 日期:2025-06-13
生物活性:Phenylephrine-d6 (hydrochloride) is deuterium labeled Phenylephrine (hydrochloride). (R)-(-)-Phenylephrine hydrochloride is a selective α1-adrenoceptor agonist with pKis of 5.86, 4.87 and 4.70 for α1D, α1B and α1A receptors respectively.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Phenylephrine-d6 hydrochloride 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:209.70Formula:C9H8D6ClNO2CAS 号:1089675-56-8非标记 CAS:61-76-7中文名称:盐酸去氧肾上腺素-d6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 &
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「同位素标记抑制剂」CAS:1266676-01-0|Crystal Violet-d6
作者:德尔塔生物 日期:2025-06-13
生物活性:Crystal Violet-d6 is the deuterium labeled Boc-Glycine[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:414.02Formula:C25H24D6ClN3CAS 号:1266676-01-0非标记 CAS:548-62-9中文名称:结晶紫-d6;龙胆紫-d6;甲紫-d6;甲基紫-d6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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「同位素标记抑制剂」CAS:940297-06-3|Venlafaxine-d6-1
作者:德尔塔生物 日期:2025-06-13
生物活性:Venlafaxine-d6-1 is deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Venlafaxine-d6-1 相关抗体:Serotonin Transporter Antibody (YA1638)HTR7 Antibody (YA2796)HTR2C Antibody (YA3364)分子量:283.44Formula:C17H21D6NO2CAS 号:940297-06-3非标记 CAS:93413-69-5中文名称:文拉法辛-d6-1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (532 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80. [Content Brief][3]. Goeringer KE, et al. Postmortem tissue concentrations of venlafaxine. Forensic Sci Int. 2001 Sep 15;
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「同位素标记抑制剂」CAS:2517378-96-8|Lidocaine-d6 hydrochloride
作者:德尔塔生物 日期:2025-06-13
生物活性:Lidocaine-d6 (hydrochloride) is deuterium labeled Lidocaine (hydrochloride). Lidocaine hydrochloride (Lignocaine hydrochloride) inhibits sodium channels involving complex voltage and using dependence[1]. Lidocaine hydrochloride decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine hydrochloride is an amide derivative and a agent to treat ventricular arrhythmia and an effective tumor-inhibitor[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Lidocaine-d6 hydrochloride 相关抗体:MEK1/2 AntibodyERK1/2 AntibodyPhospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) AntibodyNF-KB p65 AntibodyPhospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Antibody (YA455)Phospho-NF-KB p65 (Ser536) AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyPhospho-NF-κB p65 (Ser529) AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyNF-KB p65 Antibody (YA267)ERK2 Antibodyc-Myc AntibodyCyclin E1 AntibodyPhospho-MEK1 (Ser298) AntibodyxCT Antibody