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CAS:1127253-02-4|Prasugrel-d3,PCR 4099-d3

CAS:1127253-02-4|Prasugrel-d3,PCR 4099-d3

作者:德尔塔生物 日期:2025-06-10

生物活性:Prasugrel-d3 is the deuterium labeled Prasugrel. Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1].IC50 & Target:P2Y12 Receptor体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Prasugrel-d3 相关抗体:P2Y12 Antibody (YA3135)P2Y6 Antibody (YA1691)分子量:376.46Formula:C20H17D3FNO3SCAS 号:1127253-02-4非标记 CAS:150322-43-3性状:固体颜色:White to off-white中文名称:普拉格雷 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:2699607-50-4|Levofloxacin-d8 hydrochloride,盐酸左氧氟沙星-d8

CAS:2699607-50-4|Levofloxacin-d8 hydrochloride,盐酸左氧氟沙星-d8

作者:德尔塔生物 日期:2025-06-10

生物活性:Levofloxacin-d8 (hydrochloride) is deuterium labeled Levofloxacin (hydrochloride).体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:405.88Formula:C18H13D8ClFN3O4CAS 号:2699607-50-4非标记 CAS:177325-13-2性状:固体颜色:White to off-white中文名称:盐酸左氧氟沙星-d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度: ≥99.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

CAS:2254642-52-7|Prostaglandin D2-d9,PGD2-d9

CAS:2254642-52-7|Prostaglandin D2-d9,PGD2-d9

作者:德尔塔生物 日期:2025-06-10

生物活性:Prostaglandin D2-d9 is the deuterium labeled Prostaglandin D2. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals[1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances[2]. PGD2 plays a protective role by suppressing inflammation[3].IC50 & Target:DP体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Prostaglandin D2-d9 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:361.52Formula:C20H23D9O5CAS 号:2254642-52-7非标记 CAS:41598-07-6性状:液体颜色:Colorless to light yellow运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Solution, -20°C, 2 years

CAS:2741380-71-0|Ambroxol-d5 hydrochloride,NA-872-d5 hydrochloride

CAS:2741380-71-0|Ambroxol-d5 hydrochloride,NA-872-d5 hydrochloride

作者:德尔塔生物 日期:2025-06-10

生物活性:Ambroxol-d5 (hydrochloride) is the deuterium labeled Ambroxol hydrochloride. Ambroxol hydrochloride (NA-872 hydrochloride), an active metabolite of the proagent Bromhexine, has potent expectorant effects. Ambroxol hydrochloride is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol hydrochloride induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ambroxol-d5 hydrochloride 相关抗体:Glucosidase 2 subunit beta AntibodyKlotho Antibody (YA3355)GAA Antibody (YA2872)分子量:419.59Formula:C13H14D5Br2ClN2OCAS 号:2741380-71-0非标记 CAS:23828-92-4性状:固体颜色:White to off-white中文名称:盐酸氨溴索 d5 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

CAS:1173018-93-3|3-Methylxanthine-13C4,15N3

CAS:1173018-93-3|3-Methylxanthine-13C4,15N3

作者:德尔塔生物 日期:2025-06-10

生物活性:3-Methylxanthine-13C4,15N3 is the 13C-labeled and 15N-labeled 3-Methylxanthine. 3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.3-Methylxanthine-13C4,15N3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:173.09Formula:C213C4H6N15N3O2CAS 号:1173018-93-3非标记 CAS:1076-22-8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (544 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2)

CAS:1189703-33-0|Ethosuximide-d3,乙琥胺 d3

CAS:1189703-33-0|Ethosuximide-d3,乙琥胺 d3

作者:德尔塔生物 日期:2025-06-10

生物活性:Ethosuximide-d3 is the deuterium labeled Ethosuximide. Ethosuximide, a widely prescribed anti-epileptic agent, improves the phenotypes of multiple neurodegenerative disease models and blocks the low voltage activated T-type calcium channel[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ethosuximide-d3 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCardiac Troponin I/TNNC1 AntibodySCGN Antibody (YA1167)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)CRCP Antibody (YA3350)Annexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)CAB39 Antibody (YA2761)CUG BP1 Antibody (YA2806)C10orf63 Antibody (YA2894)ITPK1 Antibody (YA3125)ORAI3 Antibody (YA3128)ORAI1 Antibody (YA3157)CREB Regulated Transcription Coactivator 2 Antibody (YA3279)分子量:144.19Formula:C7H8D3NO2CAS 号:1189703-33-0非标记 CAS:77-67-8性状:固体颜色:White to off-white

CAS:1219795-37-5|Trimetazidine-d8 dihydrochloride,盐酸曲美他嗪 d8 (双盐酸盐

CAS:1219795-37-5|Trimetazidine-d8 dihydrochloride,盐酸曲美他嗪 d8 (双盐酸盐

作者:德尔塔生物 日期:2025-06-10

生物活性:Trimetazidine-d8 (dihydrochloride) is the deuterium labeled Trimetazidine dihydrochloride. Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor[1][2][3][4].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Trimetazidine-d8 dihydrochloride 相关抗体:FOXO1A AntibodyBeclin 1 AntibodyAtg12 AntibodyATG5 AntibodyBmi1 AntibodyFOXO4 AntibodyFOXP3 AntibodyGABARAP AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyPhospho-FOXO3a(Ser253) AntibodyAPG5L AntibodyATG10 Antibody (YA603)ATG3 AntibodyATG4A AntibodyATG4C AntibodyATG7 AntibodyFOXO1 Antibody (YA430)FOXO3 AntibodyFOXP3 Antibody (YA759)FTO AntibodyPhospho-FOXO3A (Ser253) AntibodyFOXO1 AntibodyATG10 AntibodyGranulin Antibody (YA1162)ATG13 Antibody (YA1650)ATG9A Antibody (YA3081)LAMP2 Antibody (YA310)WIPI1 Antibody (YA1721)ATG16L1

CAS:1346601-82-8|Deferiprone-d3,去铁酮 d3

CAS:1346601-82-8|Deferiprone-d3,去铁酮 d3

作者:德尔塔生物 日期:2025-06-10

生物活性:Deferiprone-d3 is the deuterium labeled Deferiprone. Deferiprone is the only orally active iron-chelating agent to be used therapeutically in conditions of transfusional iron overload[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Deferiprone-d3 相关抗体:Ferritin Heavy Chain AntibodyCyclophilin A AntibodyCyclophilin B Antibody (YA787)AMID/FSP1 AntibodyPeroxiredoxin 1 Antibody (YA692)PRDX3 Antibody (YA909)Ferritin Light Chain Antibody (YA971)Ferritin Light Chain Antibody (YA972)分子量:142.17Formula:C7H6D3NO2CAS 号:1346601-82-8非标记 CAS:30652-11-0性状:固体颜色:Off-white to light yellow中文名称:去铁酮 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 99.46%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Kontoghiorghes GJ, et al. Benefits and risks of deferiprone in iron overload in Thalassaemia and other conditions: comparison of epidemiological and therapeutic aspects with deferoxamine. Drug Saf. 2003;26(8):553-584. [Content Brief]

CAS:942047-64-5|Piroxicam-d3,吡罗昔康 D3; CP-16171 d3

CAS:942047-64-5|Piroxicam-d3,吡罗昔康 D3; CP-16171 d3

作者:德尔塔生物 日期:2025-06-10

生物活性:Piroxicam-d3 is deuterium labeled Piroxicam. Piroxicam is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively [1].分子量:334.36Formula:C15H10D3N3O4SCAS 号:942047-64-5非标记 CAS:36322-90-4性状:固体颜色:Light yellow to yellow中文名称:吡罗昔康 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:1353867-92-1|Albendazole-d3,阿苯哒唑-D3; SKF-62979-d3

CAS:1353867-92-1|Albendazole-d3,阿苯哒唑-D3; SKF-62979-d3

作者:德尔塔生物 日期:2025-06-10

生物活性:Albendazole-d3 is the deuterium labeled Albendazole, which is a member of the benzimidazole compounds used as a agent indicated for the treatment of a variety of worm infestations[1].分子量:268.35Formula:C12H12D3N3O2SCAS 号:1353867-92-1非标记 CAS:54965-21-8性状:固体颜色:White to off-white中文名称:阿苯达唑 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:1189469-46-2|Loperamide-d6 hydrochloride,R-18553-d6 hydrochloride

CAS:1189469-46-2|Loperamide-d6 hydrochloride,R-18553-d6 hydrochloride

作者:德尔塔生物 日期:2025-06-10

生物活性:Loperamide-d6 (hydrochloride) is a deuterium labeled Loperamide hydrochloride. Loperamide hydrochloride is an opioid receptor agonist for the treatment of diarrhea[1].分子量:519.54Formula:C29H28D6Cl2N2O2CAS 号:1189469-46-2非标记 CAS:34552-83-5性状:固体颜色:White to off-white中文名称:盐酸洛哌丁胺 d6 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

CAS:70711-53-4|Phenindione-d5,苯茚二酮 D5; Rectadione d5

CAS:70711-53-4|Phenindione-d5,苯茚二酮 D5; Rectadione d5

作者:德尔塔生物 日期:2025-06-10

生物活性:Phenindione-d5 is deuterium labeled Phenindione, which is an anticoagulant which functions as a Vitamin K antagonist.分子量:227.27Formula:C15H5D5O2CAS 号:70711-53-4非标记 CAS:83-12-5性状:固体颜色:White to off-white中文名称:苯茚二酮 d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

CAS:1356922-29-6|Enalaprilat-d5 sodium,依那普利拉钠 D5; MK-422-d5 sodium

CAS:1356922-29-6|Enalaprilat-d5 sodium,依那普利拉钠 D5; MK-422-d5 sodium

作者:德尔塔生物 日期:2025-06-10

生物活性:Enalaprilat-d5 (sodium) is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor.分子量:397.39Formula:C18H17D5N2Na2O5CAS 号:1356922-29-6性状:固体颜色:White to off-white中文名称:依那普利拉钠 d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

CAS:1392208-04-6|(Rac-Ropivacaine-d7,罗哌卡因 d7

CAS:1392208-04-6|(Rac-Ropivacaine-d7,罗哌卡因 d7

作者:德尔塔生物 日期:2025-06-10

生物活性:(Rac)-Ropivacaine-d7 is the deuterium labeled (Rac)-Ropivacaine[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(Rac)-Ropivacaine-d7 相关抗体:xCT Antibody (YA006)xCT Antibody (YA652)ATP1A1 AntibodyAlpha-ENaC AntibodyLGI1 Antibody (YA2885)CRMP2 Antibody (YA3370)SLC12A1 Antibody (YA1403)CRMP1 Antibody (YA1941)Cardiac Troponin C Antibody (YA2125)CRMP5 Antibody (YA2497)CRMP3 Antibody (YA2563)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)CRMP4 Antibody (YA2777)Kir2.1 Antibody (YA2871)分子量:281.44Formula:C17H19D7N2OCAS 号:1392208-04-6非标记 CAS:84057-95-4中文名称:罗哌卡因 d7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

CAS:1346606-66-3|Clomifene-d5 hydrochloride,Clomiphene-d5 (hydrochloride

CAS:1346606-66-3|Clomifene-d5 hydrochloride,Clomiphene-d5 (hydrochloride

作者:德尔塔生物 日期:2025-06-10

生物活性:Clomifene-d5 (hydrochloride) is a deuterium labeled Clomifene. Clomifene is an orally active compound used for infertility. Clomifene is a simple, relatively safe, easily administered and well-tolerated efficacious compound to induce ovulation[1].分子量:447.45Formula:C26H24D5Cl2NOCAS 号:1346606-66-3非标记 CAS:911-45-5性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度: 98.53%参考文献[1]. Wilkes S, et al. Ovulation induction with clomifene: a primary care perspective. J Fam Plann Reprod Health Care. 2012;38(1):48-52. [Content Brief]