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Cyanine5.5 maleimide
作者：德尔塔 日期：2022-09-27
Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5® maleimide.Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications.Cyanine5.5 can replace Cy5.5®, Alexa Fluor 680, and DyLight 680.Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5® maleimide.Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications.Cyanine5.5 can replace Cy5.5®, Alexa Fluor 680, and DyLight 680.Cas No. 1593644-50-8 SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C46H49ClN4O3 分子量 741.36 溶解度 soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L) 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice
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Cyanine5.5 hydrazide
作者：德尔塔 日期：2022-09-27
Cyanine5.5 hydrazide is a carbonyl-reactive near infrared dye. Hydrazides quickly react with carbonyl compounds, such as aldehydes and ketones, and form stable hydrazones. This reaction is useful for the preparation of labeled conjugates.Carbonyl groups in biomolecules can form spontaneously after oxidative stress or deamination of proteins. Alternatively, aldehyde groups can be specifically generated by periodate oxidation of sugar residues of glycoproteins, for example antibodies. Antibodies can be oxidized by sodium periodate and labeled with Cyanine5.5 hydrazide to form Cyanine5.5 labeled antibodies. Since sugar residues in antibodies are located far from variable, epitope-binding site, this method is particularly good for the labeling of antibodies.Cyanine5.5 is a near infrared fluorophore, an analog of Cy5.5®. It is particularly suitable for the applications which require low fluorescence background. The absorption and emission wavelength of the dye exhibit significant tissue penetration, so Cyanine5.5 is suitable for in vivo NIR imaging applications.Cyanine5.5 hydrazide is a carbonyl-reactive near infrared dye. Hydrazides quickly react with carbonyl compounds, such as aldehydes and ketones, and form stable hydrazones. This reaction is useful for the preparation of labeled conjugates.Carbonyl groups in biomolecules can form spontaneously after oxidative stress or deamination of proteins. Alternatively, aldehyde groups can be specifically generated by periodate oxidation of sugar residues of glycoproteins, for example antibodies. Antibodies can be oxidized by sodium pe
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Cyanine5.5 DBCO
作者：德尔塔 日期：2022-09-27
Strain promoted alkyne azide cycloaddition (spAAc) between strained cycloalkynes and azides is a useful bioconjugation method that eliminates the need for copper catalyst necessary for classical CuAAc Click chemistry.Cyanine5.5 DBCO is a cyclooctyne product containing Cyanine5.5 fluorescent dye. This fluorophore is used in bioimaging, biodistribution studies, and microscopy.Cyanine5.5 DBCO can be used to conjugate the fluorophore with various azides.Strain promoted alkyne azide cycloaddition (spAAc) between strained cycloalkynes and azides is a useful bioconjugation method that eliminates the need for copper catalyst necessary for classical CuAAc Click chemistry.Cyanine5.5 DBCO is a cyclooctyne product containing Cyanine5.5 fluorescent dye. This fluorophore is used in bioimaging, biodistribution studies, and microscopy.Cyanine5.5 DBCO can be used to conjugate the fluorophore with various azides.Cas No. N/A SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C61H63N4F6O2P 分子量 1029.14 溶解度 good in DMF, DMSO, chlorinated organic solvents 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips Fo
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Cyanine5.5 carboxylic acid
作者：德尔塔 日期：2022-09-27
Cyanine5.5 dye, free acid form, unactivated. The dye can be considered non-reactive for most applications. It can be used as a control or reference sample, and for instrument calibration.Pre-activated NHS ester for the labeling of amine groups is also available.Cyanine5.5 dye, free acid form, unactivated. The dye can be considered non-reactive for most applications. It can be used as a control or reference sample, and for instrument calibration.Pre-activated NHS ester for the labeling of amine groups is also available.Cas No. 1449661-34-0 (without anion), 1449612-07-0 (inner salt) SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C40H43ClN2O2 分子量 619.23 溶解度 soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L) 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other
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Cyanine5.5 azide
作者：德尔塔 日期：2022-09-27
This Cyanine5.5 labeling reagent is a dye azide for Click Chemistry, available as 10 mM solution in DMSO, or in solid form. The dye possesses far red / near infrared emission, which allows to use it for NIR live organism imaging. Cyanine5.5 can replace Cy5.5®, Alexa Fluor 680, and DyLight 680.This Cyanine5.5 labeling reagent is a dye azide for Click Chemistry, available as 10 mM solution in DMSO, or in solid form. The dye possesses far red / near infrared emission, which allows to use it for NIR live organism imaging. Cyanine5.5 can replace Cy5.5®, Alexa Fluor 680, and DyLight 680.Cas No. N/A SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C43H49ClN6O 分子量 701.34 溶解度 soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (1.6 uM, 1.2 mg/L) 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice
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Cyanine5.5 amine
作者：德尔塔 日期：2022-09-27
Cyanine5.5 (Cy5.5® analog) amine derivative. The dye contains a free amine group which can be conjugated with a variety of functionalities, including NHS esters, and epoxides.Cyanine5.5 is a far red dye which works fine for live organism imaging, and applications requiring low fluorescence background.Cyanine5.5 (Cy5.5® analog) amine derivative. The dye contains a free amine group which can be conjugated with a variety of functionalities, including NHS esters, and epoxides.Cyanine5.5 is a far red dye which works fine for live organism imaging, and applications requiring low fluorescence background.Cas No. 2097714-44-6 (without anion), 2097714-45-7 (chloride) SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C46H58Cl2N4O 分子量 753.88 溶解度 practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols) 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : shi
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Cyanine5.5 alkyne
作者：德尔塔 日期：2022-09-27
Far red/near infrared dye for Click Chemistry labelingCyanine5.5 alkyne is a far red/near infrared dye alkyne with an ethynyl group for Click Chemistry labeling. Cyanine5.5 is an analog of Cy5.5®, a popular fluorophore which has been widely used for various applications including intact organism imaging. Cyanine5.5 alkyne can be conjugated with azido groups under mild copper catalyzed Click Chemistry conditions.Cyanine5.5 alkyne is soluble in organic solvents, but mixtures of water with small percent of DMSO can be used for efficient conjugation. Cyanine5.5 alkyne can also be used for the labeling of small molecules.Cyanine5.5 alkyne is a far red/near infrared dye alkyne with an ethynyl group for Click Chemistry labeling. Cyanine5.5 is an analog of Cy5.5®, a popular fluorophore which has been widely used for various applications including intact organism imaging. Cyanine5.5 alkyne can be conjugated with azido groups under mild copper catalyzed Click Chemistry conditions.Cyanine5.5 alkyne is soluble in organic solvents, but mixtures of water with small percent of DMSO can be used for efficient conjugation. Cyanine5.5 alkyne can also be used for the labeling of small molecules.Cas No. 1628790-37-3 SDF 别名 N/A 化学名 1,1-dimethyl-3-(6-oxo-6-(prop-2-yn-1-ylamino)hexyl)-2-((1E,3E,5E)-5-(1,1,3-trimethyl-1H-benzo[e]indol-2(3H)-ylidene)penta-1,3-dien-1-yl)-1H-benzo[e]indol-3-ium chloride Canonical SMILES CN1C2
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Cyanine5 tetrazine
作者：德尔塔 日期：2022-09-27
Tetrazine-cyclooctene (TCO) ligation is one of the fastest bioconjugation reactions known to date. In order to use it for fluorescent labeling, a fluorescent reporter molecule bearing one of the reacting groups is necessary.Cyanine5 tetrazine is a molecule bearing Cyanine5 fluorophore, and tetrazine moiety. Cyanine5 is a very popular fluorophore compatible with numerous instruments.Tetrazine-cyclooctene (TCO) ligation is one of the fastest bioconjugation reactions known to date. In order to use it for fluorescent labeling, a fluorescent reporter molecule bearing one of the reacting groups is necessary.Cyanine5 tetrazine is a molecule bearing Cyanine5 fluorophore, and tetrazine moiety. Cyanine5 is a very popular fluorophore compatible with numerous instruments.Cas No. N/A SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C42H48N7F6OP 分子量 811.84 溶解度 good in DMF, DMSO, DCM 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Con
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Cyanine5 NHS ester iodide
作者：德尔塔 日期：2022-09-27
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotidesCyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides[1].Cyanine-5 NHS ester amine-reactive red emitting fluorescent dye is used to react with the free amino group on the cysteine amino acid present in terminal peptides used for end-capping Poly(β-amino esters) (pBAEs) backbones[1].Reference:[1]. Brugada-Vilà P, et al. Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses. Theranostics. 2020;10(6):2744-2758.Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides[1].Cyanine-5 NHS ester amine-reactive red emitting fluorescent dye is used to react with the free amino group on the cysteine amino acid present in terminal peptides used for end-capping Poly(β-amino esters) (pBAEs) backbones[1].Reference:[1]. Brugada-Vilà P, et al. Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses. Theranostics. 2020;10(6):2744-2758.Cas No. N/A SDF N/A 别名 N/A 化学名 N/A Canonical SMILES CC1(C)C(/C=C/C=C/C=C2N(C)C3=C(C=CC=C3)C\
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Cyanine5 NHS ester chloride
作者：德尔塔 日期：2022-09-27
Cyanine5NHSesterchloride是一种红色荧光染料，用于标记肽、蛋白质和寡核苷酸中的氨基。Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides[1].[1]. Brugada-VilÀ P, et al. Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses. Theranostics. 2020;10(6):2744-2758. Published 2020 Feb 3.Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides[1].[1]. Brugada-VilÀ P, et al. Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses. Theranostics. 2020;10(6):2744-2758. Published 2020 Feb 3.Cas No. 1032678-42-4 SDF 别名 N/A 化学名 N/A Canonical SMILES CC1(C)C(/C=C/C=C/C=C2N(C)C3=C(C=CC=C3)C\2(C)C)=[N+](CCCCCC(ON4C(CCC4=O)=O)=O)C5=C1C=CC=C5.[Cl-] 分子式 C36H42ClN3O4 分子量 616.19 溶解度 N/A 储存条件 N/A General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation s
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Cyanine5 NHS ester
作者：德尔塔 日期：2022-09-27
During the last years, Cyanine5 (an analog of Cy5®) has become an incredibly popular label in life science research and diagnostics. The fluorophore has its emission maximum in the red region, where many CCD detectors exhibit maximum sensitivity, and biological objects show low background. The dye color is very intense, therefore quantities as small as 1 nmol can be detected in gel electrophoresis by naked eye.This Cyanine5 NHS ester (analog to Cy5® NHS ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires a small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reactions (please see our recommended protocol for more details). This reagent is ideal for very cost-efficient labeling of soluble proteins as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. For more sophisticated targets such as easily degradable proteins, when the use of DMF or DMSO is undesirable, consider using water-soluble sulfo-Cyanine 5 NHS ester which does not require any co-solvent, and features very similar fluorescent properties.Cyanine5 fluorophore is compatible with various instrumentation including many fluorescent microscopes, imagers, scanners, and fluorescence readers. A number of various Cyanine5 analogs exist - Cyanine5 NHS ester can replace activated esters of Cy5®, Alexa Fluor 647, and DyLight 649.During the last years, Cyanine5 (an analog of Cy5®) has become an incredibly popular label in life science research and diagnos
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Cyanine5 hydrazide
作者：德尔塔 日期：2022-09-27
Cyanine5 hydrazide is a reactive dye for the labeling of aldehydes and ketones, an analog of Cy5® hydrazide.This dye reacts smoothly and nearly quantitatively with various carbonyl groups encountered in biomolecules. Examples are proteins subjected to oxidative stress, glycosylated proteins pre-activated by periodate oxidation (including antobodies), and oligonucleotides with aldehyde moieties.Cyanine5 hydrazide replaces carbonyl-reactive Cy5®, Alexa Fluor 647, DyLight 649 dyes.Cyanine5 hydrazide is a reactive dye for the labeling of aldehydes and ketones, an analog of Cy5® hydrazide.This dye reacts smoothly and nearly quantitatively with various carbonyl groups encountered in biomolecules. Examples are proteins subjected to oxidative stress, glycosylated proteins pre-activated by periodate oxidation (including antobodies), and oligonucleotides with aldehyde moieties.Cyanine5 hydrazide replaces carbonyl-reactive Cy5®, Alexa Fluor 647, DyLight 649 dyes.Cas No. 1427705-31-4 SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C32H42Cl2N4O 分子量 569.61 溶解度 moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols) 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prol
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Cyanine5 DBCO
作者：德尔塔 日期：2022-09-27
A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free Click chemistry.Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain promoted alkyne azide cycloaddition (spAAC). This reaction is very fast, mild, and biocompatible.Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free Click chemistry.Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain promoted alkyne azide cycloaddition (spAAC). This reaction is very fast, mild, and biocompatible.Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.Cas No. N/A SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C53H59N4F6O2P 分子量 929.03 溶解度 good in DMF, DMSO, chlorinated organic solvents, practically insoluble in water (
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Cyanine5 carboxylic acid
作者：德尔塔 日期：2022-09-27
Non-activated carboxylic acid, an analog of Cy5® free carboxylic acid. Contains Cyanine5 fluorophore.This dye has limited water solubility, but can be dissolved in mixtures of water with organic phase (DMF, DMSO, alcohols) to obtain useful concentrations of the material in solution. Water-soluble version is available.This molecule can be considered non-reactive dye for the use in control samples, and for instrument calibration. For coupling with amines and protein labeling, consider using Cyanine5 NHS ester, or water-soluble sulfo-Cyanine5 NHS ester.Non-activated carboxylic acid, an analog of Cy5® free carboxylic acid. Contains Cyanine5 fluorophore.This dye has limited water solubility, but can be dissolved in mixtures of water with organic phase (DMF, DMSO, alcohols) to obtain useful concentrations of the material in solution. Water-soluble version is available.This molecule can be considered non-reactive dye for the use in control samples, and for instrument calibration. For coupling with amines and protein labeling, consider using Cyanine5 NHS ester, or water-soluble sulfo-Cyanine5 NHS ester.Cas No. 1032678-07-1 (chloride), 195867-59-5 (inner salt), 766503-38-2 (without anion) SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C32H39ClN2O2 分子量 519.12 溶解度 soluble in organic solvents (DMF, DMS
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Cyanine5 Boc-hydrazide
作者：德尔塔 日期：2022-09-27
Boc-protected Cyanine5 hydrazide reactive dye for the labeling of aldehydes and ketones.Boc- (tert-butoxycarbonyl) protective group can be removed with trifluoroacetic acid, or other strong acid. Reactive hydrazide is formed, which can then couple with various carbonyl groups yielding Cyanine5-labeled molecules.Boc-protected Cyanine5 hydrazide reactive dye for the labeling of aldehydes and ketones.Boc- (tert-butoxycarbonyl) protective group can be removed with trifluoroacetic acid, or other strong acid. Reactive hydrazide is formed, which can then couple with various carbonyl groups yielding Cyanine5-labeled molecules.Cas No. N/A SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C37H49ClN4O3 分子量 633.26 溶解度 good in dichloromethane, polar organic solvents (DMF, DMSO), alcohols, low in water 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice
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