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Pleconaril-d4，普可那利-d4; VP 63843-d4; Win 63843-d4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Pleconaril-d4 is deuterium labeled Pleconaril.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：385.37Formula：C18H14D4F3N3O3CAS 号：2749329-20-0非标记 CAS：153168-05-9中文名称：普可那利-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Benschop KS, et al. Genetic and antigenic structural characterization for resistance of echovirus 11 to pleconaril in an immunocompromised patient. J Gen Virol. 2015 Mar;96(Pt 3):571-9. [Content Brief][3]. Lacroix C, et al. http://www.ncbi.nlm. In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses. Virol J. 2015 Jul 14;12:106. [Content Brief]
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Tauroursodeoxycholate-d4，牛磺熊去氧胆酸-d4; Tauroursodeoxycholic acid-d4; TUDCA-d4; UR 906-d4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Tauroursodeoxycholate-d4 is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Tauroursodeoxycholate-d4 相关抗体:Cleaved-Caspase 9 AntibodyBNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)ERK1/2 AntibodyPhospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) AntibodyPhospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Antibody (YA455)E-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyCleaved-Caspase 1 AntibodyCleaved-Caspase 3 p12 AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCaspase-3 AntibodyCaspase-9 AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyMETTL3 AntibodyERK2 AntibodyCaspase 7 Antibodyc-Myc AntibodyCyclin E1 AntibodyTSG101 Antibody分子量：503.73Formula：C26H41D4NO6SCAS 号：2410279-94-4非标记 CAS：14605-22-2中文名称：牛磺熊去氧胆酸-d4；牛磺熊脱氧胆酸
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Baquiloprim-d6，巴喹普林-d6「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Baquiloprim-d6 is deuterium labeled Baquiloprim. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Baquiloprim-d6 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：314.42Formula：C17H14D6N6CAS 号：1228182-50-0非标记 CAS：102280-35-3中文名称：巴喹普林-d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (533 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmac
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Ceramide C6-d7「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Ceramide C6-d7 is the deuterium labeled Ceramide C6. Ceramide C6, a Ceramide pathway activator, is an exogenous short-chain ceramide which can induce apoptosis of multiple cancer cells[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ceramide C6-d7 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量：404.68Formula：C24H40D7NO3CAS 号：2692624-22-7非标记 CAS：124753-97-5性状：液体颜色：Colorless to light yellow运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Solution, -20°C, 2 years纯度 & 产品资料纯度： ≥99.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pha
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(±-Levomepromazine-d3，(±-左美丙嗪-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：(±)-Levomepromazine-d3 is deuterium labeled (±)-Levomepromazine.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：331.49Formula：C19H21D3N2OSCAS 号：1185071-29-7非标记 CAS：851-68-3中文名称：(±)-左美丙嗪-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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Monoethylglycinexylidide-d6「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Monoethylglycinexylidide-d6 is deuterium labeled Monoethylglycinexylidide.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：212.32Formula：C12H12D6N2OCAS 号：1216698-89-3非标记 CAS：7728-40-7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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22(R-Hydroxycholesterol-d7，Narthesterol-d7「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：22(R)-Hydroxycholesterol-d7 is deuterium labeled 22(R)-Hydroxycholesterol.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：409.70Formula：C27H39D7O2CAS 号：1246302-93-1非标记 CAS：17954-98-2中文名称：22(R)-羟基胆固醇-d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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D-Erythrose-2-13C「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：D-Erythrose-2-13C is the 13C labeled D-Erythrose[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：121.10Formula：C313CH8O4CAS 号：83434-88-2非标记 CAS：583-50-6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (517 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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D-Erythrose-1-13C「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：D-Erythrose-1-13C is the 13C labeled D-Erythrose[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：121.10Formula：C313CH8O4CAS 号：70849-19-3非标记 CAS：583-50-6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (518 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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(±-Penbutolol-d9 hydrochloride，(Rac-Penbutolol-d9 hydrochloride; (±-Isopenbutolol-d9 hydrochloride「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：(±)-Penbutolol-d9 (hydrochloride) is a deuterium labeled (±)-Penbutolol hydrochloride. (+)-Penbutolol hydrochloride is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM[1].IC50 & Target：β adrenergic receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(±)-Penbutolol-d9 hydrochloride 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：336.94Formula：C18H21D9ClNO2CAS 号：1346605-01-3非标记 CAS：36507-48-9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Chen M, et al. Effects of beta-adrenoceptor antagonists on Ca(2+)-overload induced by lysophosphatidylcholine in rat isolated cardiomyocytes. Br J Pharmacol. 1996 Jun;118(4):865-70. [Content Brief][2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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3-Hydroxycarbofuran-d3，3-羟基呋喃丹-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：3-Hydroxycarbofuran-d3 is a deuterium labeled compound.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：240.27Formula：C12H12D3NO4CAS 号：1794759-59-3非标记 CAS：16655-82-6中文名称：3-羟基呋喃丹-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (523 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246. [Content Brief]
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1,2-Distearoyl-sn-glycero-3-phosphate-d70 sodium，二硬脂酰磷脂酸-d70「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：1,2-Distearoyl-sn-glycero-3-phosphate-d70 (sodium) is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphate.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：797.41Formula：C39H6D70NaO8PCAS 号：327179-02-2非标记 CAS：108321-18-2中文名称：二硬脂酰磷脂酸-d70运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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Parbendazole-d3，帕苯咪唑-d3; SKF 2904-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Parbendazole-d3 is the deuterium labeled Parbendazole. Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530 nM, and exhibits a broad-spectrum anthelmintic activity.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Parbendazole-d3 相关抗体:alpha Tubulin AntibodyLC3A/B AntibodyBeta Tubulin Antibodybeta Tubulin Antibody (YA839)Doublecortin AntibodyLC3B Antibody (YA308)Stathmin 1 Antibody (YA049)Stathmin 1 Antibody (YA050)alpha Tubulin (acetyl K40) Antibodybeta III Tubulin Antibodygamma Tubulin AntibodyLC3B AntibodyBeta Tubulin Antibody (HRP) (YA865)Cytokeratin 5 AntibodyMAP2 AntibodyDM1 Antibody (YA898)CK18 AntibodyCytokeratin 19 AntibodyCytokeratin 7 Antibody (YA951)Cytokeratin 15 Antibody (YA1493)p63 Antibody (YA1531)Cytokeratin 6 Antibody (YA1701)Cytokeratin 4 Antibody (YA1762)Cytokeratin 10 Antibody (YA1857)Cytokeratin 14 Antibody (YA1876)Cytokeratin 1 Antibody (YA2665)Stanniocalcin 1 Antibody (YA2690)Cytokeratin 13 Antibody (YA2695)HRH3 Antibody (YA2701)Phospho-alpha Tubulin (Tyr272) Antibody (YA3041)分子量：250.31Formula：C13H14D3N3O2CAS 号：1613439-58-9非标记 CAS：14255-87-9中文名称：帕苯咪唑-d3； 丁苯咪唑-d3运输条件：Room temperature in contine
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N-butyryl-L-Homoserine lactone-d5，N-丁酰基-L-高丝氨酸内酯 d5「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：N-butyryl-L-Homoserine lactone-d5 is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.N-butyryl-L-Homoserine lactone-d5 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：176.22Formula：C8H8D5NO3CAS 号：2701379-46-4非标记 CAS：67605-85-0中文名称：N-丁酰基-L-高丝氨酸内酯 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product
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MRTX-1257-d6「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：MRTX-1257-d6 is the deuterium labeled MRTX-1257 (HY-114436). MRTX-1257 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells[1][2].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：571.75Formula：C33H33D6N7O2CAS 号：2639608-44-7非标记 CAS：2206736-04-9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (537 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. [Content Brief][2]. Matthew et al. Structure-Based Drug Discovery of MRTX1257, a Selective, Covalent KRAS G12C Inhibitor with Oral Activity in Animal Models of Cancer.
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