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Melperone-d4 hydrochloride「同位素标记抑制剂」

Melperone-d4 hydrochloride「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Melperone-d4 hydrochloride is the deuterium labeled Melperone hydrochloride (HY-103109)[1]. Melperone hydrochloride is a butyrophenone with atypical antipsychotic properties. Melperone hydrochloride is a multireceptor antagonist with Kds of 102 nM, 180 nM, 180 nM, and 150 nM for 5-HT2A, dopamine D2, α1-adrenergic, and α2-adrenergic receptors, respectively. Melperone hydrochloride has weak binding to histamine H1, 5-HT2C, 5-HT1A, 5-HT1D, and muscarinic receptors, with Kd values ​​of 580 nM, 2100 nM, 2200 nM, 3400 nM, >10000 nM, respectively. Melperone hydrochloride is also a CYP2D6 inhibitor. Melperone hydrochloride can be used for the study of schizophrenia, and agitation in the elderly[2][3][4][5].IC50 & Target[3][5]Human D2 Receptor180 nM (Kd)α1-adrenergic receptor180 nM (Kd)α2-adrenergic receptor150 nM (Kd)CYP2D6体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Melperone-d4 hydrochloride 相关抗体:Cytochrome C AntibodyCytochrome P450 17A1 AntibodyAromatase AntibodyADRB2 AntibodyDRD2 AntibodyMTNR1A AntibodyCYP11A1 AntibodyDopamine Receptor D3 Antibody (YA1742)Cytochrome P450 1B1 Antibody (YA1836)Adrenodoxin Antibody (YA2005)Cytochrome P450 27A1 Antibody (YA2163)Cytochrome P450 2C9 Antibody (YA2166)Cytochrome P450 2E1 Antibody (YA2302)DOPA Decarboxylase Antibody (YA2428)Cytochrome P450 Reductase Antibody (YA2619)Thromboxane A Synthase Antibody (YA2670)Dopa

Ditiocarb-d10,Diethyldithiocarbamic acid-d10「同位素标记抑制剂」

Ditiocarb-d10,Diethyldithiocarbamic acid-d10「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Ditiocarb-d10 (Diethyldithiocarbamic acid-d10) is the deuterium labeled Ditiocarb (HY-126363)[1]. Ditiocarb (Diethyldithiocarbamic acid) is an accelerator of the rate of copper cementation. Ditiocarb (Diethyldithiocarbamic acid) reduces the incidence of HIV infection, and also enhances adjuvant immunoresearch of high risk breast cancer[2][3][4].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ditiocarb-d10 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)Tat SF1 Antibody (YA2886)分子量:159.34Formula:C5HD10NS2CAS 号:1261734-83-1非标记 CAS:147-84-2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (543 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Abeer A.El-Saharty, et al. Sodium diethyldithiocarbamate as accelerator of the rate of copper cementation. The Egyptian Journal of Aquatic Research. 2015 Dec, Volume 41(4):289-293.[3]. Hersh EM, et al. Ditiocarb sodium (diethyldithiocarbamate) therapy in patients with symptomatic HIV infection and AIDS. A randomized, double-blind, placebo-controlled, m

4-Hydroxy Atorvastatin-d5 hemicalcium「同位素标记抑制剂」

4-Hydroxy Atorvastatin-d5 hemicalcium「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:4-Hydroxy Atorvastatin-d5 (calcium) is the deuterium labeled 4-Hydroxy Atorvastatin calcium[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:599.71Formula:C33H30D5FN2O6.1/2CaCAS 号:265989-45-5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

Thiamphenicol-d3-1,甲砜霉素; Thiophenicol-d3-1; Dextrosulphenidol-d3-1「同位素标记抑制剂」

Thiamphenicol-d3-1,甲砜霉素; Thiophenicol-d3-1; Dextrosulphenidol-d3-1「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479)[1]. Thiamphenicol (Thiophenicol),a methyl-sulfonyl derivative of Chloramphenicol,is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit,leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative,Gram-positive aerobic and anaerobic bacteria)[2][3].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:359.24Formula:C12H12D3Cl2NO5SCAS 号:1217723-41-5非标记 CAS:19934-71-5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (538 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Clomiphene-d5 citrate,氯米芬柠檬酸盐 d5 (柠檬酸盐; Clomifene-d5 citrate; (Z/E-Enclomiphene-d5 citrate; (Z/E-Enclomifene-d5 citrate「同位素标记抑制剂」

Clomiphene-d5 citrate,氯米芬柠檬酸盐 d5 (柠檬酸盐; Clomifene-d5 citrate; (Z/E-Enclomiphene-d5 citrate; (Z/E-Enclomifene-d5 citrate「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Clomiphene-d5 (citrate) is the deuterium labeled Enclomiphene citrate. Enclomiphene citrate is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Clomiphene-d5 citrate 相关抗体:Estrogen Receptor alpha Antibody (YA768)Estrogen Receptor alpha AntibodyGPR30 AntibodyPBR Antibody (YA1785)REA Antibody (YA1848)Estrogen Related Receptor gamma Antibody (YA2009)ERR alpha Antibody (YA2283)Estrogen Receptor beta Antibody (YA1892)14-3-3 Antibody (YA1949)Estrogen Inducible Protein pS2 Antibody (YA2377)MVK Antibody (YA3093)分子量:603.11Formula:C32H31D5ClNO8CAS 号:1217200-17-3非标记 CAS:50-41-9中文名称:氯米芬柠檬酸盐 d5 (柠檬酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief][2]. Fontenot GK, et al. Differential effects of isomers of clomiphene citrate on reproductive tissues in male mice.

Lofepramine-d3「同位素标记抑制剂」

Lofepramine-d3「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Lofepramine-d3 (Lopramine-d3) is the deuterium labeled Lofepramine. Lofepramine (Lopramine) is a potent tricyclic antidepressant and is extensively metabolised to Desipramine. The antidepressant activity of Lofepramine stems from the facilitation of noradrenergic neurotransmission by uptake inhibition. Lofepramine may also potentiate serotoninergic neurotransmission by inhibition of the neuronal uptake of serotonin and the enzyme tryptophan pyrrolase. Lofepramine has significant anxiolytic efficacy in addition to its antidepressant properties[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:421.98Formula:C26H24D3ClN2OCAS 号:1185083-78-6非标记 CAS:23047-25-8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (533 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Lancaster SG, et al. Lofepramine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness. Drug

Tiopronin-13C,d3,硫普罗宁 13C, d3「同位素标记抑制剂」

Tiopronin-13C,d3,硫普罗宁 13C, d3「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Tiopronin-13C,d3 is deuterium labeled Tiopronin.分子量:167.21Formula:C413CH6D3NO3SCAS 号:1189695-13-3非标记 CAS:1953-02-2性状:固体颜色:White to off-white中文名称:硫普罗宁 13C, d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 95.30%选择批次:HY-B0373S-36****Data Sheet (491 KB)SDS (252 KB)COA (192 KB)HNMR (158 KB)RP-HPLC (137 KB)MS (230 KB)产品使用指南 (1538 KB)

Emtricitabine-15N,d2,BW1592-15N,d2「同位素标记抑制剂」

Emtricitabine-15N,d2,BW1592-15N,d2「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Emtricitabine-15N,d2 is a 15N-labeled and deuterium labeled Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Emtricitabine-15N,d2 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)CD4 AntibodyLamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 Antibody分子量:250.25Formula:C8H8D2FN215NO3SCAS 号:2714436-53-8非标记 CAS:143491-57-0性状:固体颜色:White to off-white中文名称:恩曲他滨 15N,d2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (pro

Levulinic acid-d5,乙酰丙酸-d5; 4-Oxovaleric acid-d5; NSC 3716-d5「同位素标记抑制剂」

Levulinic acid-d5,乙酰丙酸-d5; 4-Oxovaleric acid-d5; NSC 3716-d5「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Levulinic acid-d5 is the deuterium labeled Levulinic acid[1]. Levulinic acid is a precursor for the synthesis of biofuels, such as ethyl levulinate[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Levulinic acid-d5 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:121.15Formula:C5H3D5O3CAS 号:1206185-52-5非标记 CAS:123-76-2性状:液体颜色:Colorless to light yellow中文名称:乙酰丙酸-d5; 果糖酸-d5; 左旋糖酸-d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Pure form-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参

Brexpiprazole-d8-1,OPC-34712-d8-1「同位素标记抑制剂」

Brexpiprazole-d8-1,OPC-34712-d8-1「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Brexpiprazole-d8-1 (OPC-34712-d8-1) is the deuterium labeled Brexpiprazole (HY-15780)[1]. Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM)[2][3].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Brexpiprazole-d8-1 相关抗体:ADRB2 AntibodyDRD2 AntibodyMTNR1A AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Salbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量:441.62Formula:C25H19D8N3O2SCAS 号:1427049-19-1非标记 CAS:913611-97-9性状:固体颜色:Off-white to light yellow中文名称:依匹哌唑-d8-1;依匹唑派-d8-1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)纯度 & 产品资料纯度: 96.48%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216

Nateglinide-d5,A4166 d5; Senaglinide d5「同位素标记抑制剂」

Nateglinide-d5,A4166 d5; Senaglinide d5「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Nateglinide-d5 is a deuterium labeled Nateglinide. Nateglinide, a D-phenylalanine derivative, is an orally active and short-acting insulinotropic agent and a DPP IV inhibitor. Nateglinide inhibits ATP-sensitive K+ channels in pancreatic β-cells. Nateglinide is used for the treatment of type 2 (non-insulin-dependent) diabetes mellitus[1][2].IC50 & Target:DPP-4体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nateglinide-d5 相关抗体:ATP1A1 AntibodyLGI1 Antibody (YA2885)DPP4/CD26 Antibody (YA1274)Cardiac Troponin C Antibody (YA2125)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)Kir2.1 Antibody (YA2871)分子量:322.45Formula:C19H22D5NO3CAS 号:1227666-13-8非标记 CAS:105816-04-4性状:固体颜色:White to off-white中文名称:那格列奈 d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

p,p'-DDD-d8,4,4'-DDD-d8; p,p'-Dichlorodiphenyl dichloroethane-d8「同位素标记抑制剂」

p,p'-DDD-d8,4,4'-DDD-d8; p,p'-Dichlorodiphenyl dichloroethane-d8「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:p,p'-DDD-d8 is the deuterium labeled p,p'-DDD[1]. p,p'-DDD (4,4’-DDD) is an organochlorine insecticide, a major metabolite of p,p'-DDT. p,p'-DDD is an agonist at estrogen receptor α(ERα) and ERβ. p,p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p,p'-DDD stimulates cell proliferation in SKBR3 cells. p,p'-DDD activates the AP-1 transcription factor. p,p'-DDD decreases sleep times of barbiturates and steroids in rats[1][2][3][4][5].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.p,p'-DDD-d8 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量:328.09Formula:C14H2D8Cl4CAS 号:93952-20-6非标记 CAS:72-54-8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资

Losartan-d2,氯沙坦-d2; DuP-753-d2「同位素标记抑制剂」

Losartan-d2,氯沙坦-d2; DuP-753-d2「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Losartan-d2 is the deuterium labeled Losartan[1]. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Losartan-d2 相关抗体:Natriuretic Peptides A Antibody (YA1381)Angiotensinogen Antibody (YA2097)Natriuretic Peptides B Antibody (YA999)Natriuretic Peptides B Antibody (YA1000)Natriuretic Peptides B Antibody (YA1001)AGTR2 Antibody (YA3090)Angiotensin II Type 1 Receptor Antibody (YA3358)分子量:424.92Formula:C22H21D2ClN6OCAS 号:1030936-22-1非标记 CAS:114798-26-4中文名称:氯沙坦-d2; 洛沙坦-d2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (534 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Burnier, M. Angiotensin II type 1 receptor blockers. Circulation, 2001. 103(6): p. 904-12.;Ashry, O., et al. Evidence for expression and function of angiotensin II receptor type 1 in pulmonary epithel

Losartan-d9,氯沙坦-d9; DuP-753-d9「同位素标记抑制剂」

Losartan-d9,氯沙坦-d9; DuP-753-d9「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Losartan-d9 is the deuterium labeled Losartan[1]. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Losartan-d9 相关抗体:Natriuretic Peptides A Antibody (YA1381)Angiotensinogen Antibody (YA2097)Natriuretic Peptides B Antibody (YA999)Natriuretic Peptides B Antibody (YA1000)Natriuretic Peptides B Antibody (YA1001)AGTR2 Antibody (YA3090)Angiotensin II Type 1 Receptor Antibody (YA3358)分子量:431.97Formula:C22H14D9ClN6OCAS 号:1030937-18-8非标记 CAS:114798-26-4中文名称:氯沙坦-d9;洛沙坦-d9运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Burnier, M. Angiotensin II type 1 receptor blockers. Circulation, 2001. 103(6): p. 904-12. [Content Brief][3]. Ashry, O., et al. Evidence for expression and function of angiotensin II receptor type 1 i

DPPG-d62,1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol-d62 sodium「同位素标记抑制剂」

DPPG-d62,1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol-d62 sodium「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:DPPG-d62 (sodium) is deuterium labeled DPPG. DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, l体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:807.33Formula:C38H12D62NaO10PCAS 号:326495-46-9非标记 CAS:200880-41-7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Ege C, Lee KY. Insertion of Alzheimer's A beta 40 peptide into lipid monolayers. Biophys J. 2004 Sep;87(3):1732-40.  [Content Brief][2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]