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Telmisartan-d7，BIBR 277-d7「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Telmisartan-d7 (BIBR 277-d7) is a deuterium labeled Telmisartan (HY-13955). Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Telmisartan-d7 相关抗体:Natriuretic Peptides A Antibody (YA1381)Angiotensinogen Antibody (YA2097)Natriuretic Peptides B Antibody (YA999)Natriuretic Peptides B Antibody (YA1000)Natriuretic Peptides B Antibody (YA1001)AGTR2 Antibody (YA3090)Angiotensin II Type 1 Receptor Antibody (YA3358)分子量：521.66Formula：C33H23D7N4O2CAS 号：1794754-60-1非标记 CAS：144701-48-4中文名称：替米沙坦 d4-d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (544 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246. [Content Brief][2]. Maillard MP, et al. In vitro and in vivo characterization of the activity of telmisartan: an insurmountable angiotensin II receptor antagonist. J Pharmacol Exp Ther. 2002 Sep;302(3):1089-95. [Content Brief][3]. Xuan H, et al. Inhibition or deletion of angiotensin II type 1 receptor sup
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Rifampicin-d3，Rifampin-d3; Rifamycin AMP-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Rifampicin-d3 is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Rifampicin-d3 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Poliovirus Receptor Antibody (YA2556)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：825.96Formula：C43H55D3N4O12CAS 号：1262052-36-7非标记 CAS：13292-46-1性状：固体颜色：Orange to red中文名称：利福平 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)纯度 & 产品资料纯度： 95.03%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 201
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Ethosuximide-d3，乙琥胺 d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Ethosuximide-d3 is the deuterium labeled Ethosuximide. Ethosuximide, a widely prescribed anti-epileptic agent, improves the phenotypes of multiple neurodegenerative disease models and blocks the low voltage activated T-type calcium channel[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ethosuximide-d3 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCardiac Troponin I/TNNC1 AntibodySCGN Antibody (YA1167)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)CRCP Antibody (YA3350)Annexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)CAB39 Antibody (YA2761)CUG BP1 Antibody (YA2806)C10orf63 Antibody (YA2894)ITPK1 Antibody (YA3125)ORAI3 Antibody (YA3128)ORAI1 Antibody (YA3157)CREB Regulated Transcription Coactivator 2 Antibody (YA3279)分子量：144.19Formula：C7H8D3NO2CAS 号：1189703-33-0非标记 CAS：77-67-8性状：固体颜色：White to off-white
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Trimetazidine-d8 dihydrochloride，盐酸曲美他嗪 d8 (双盐酸盐「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Trimetazidine-d8 (dihydrochloride) is the deuterium labeled Trimetazidine dihydrochloride. Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor[1][2][3][4].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Trimetazidine-d8 dihydrochloride 相关抗体:FOXO1A AntibodyBeclin 1 AntibodyAtg12 AntibodyATG5 AntibodyBmi1 AntibodyFOXO4 AntibodyFOXP3 AntibodyGABARAP AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyPhospho-FOXO3a(Ser253) AntibodyAPG5L AntibodyATG10 Antibody (YA603)ATG3 AntibodyATG4A AntibodyATG4C AntibodyATG7 AntibodyFOXO1 Antibody (YA430)FOXO3 AntibodyFOXP3 Antibody (YA759)FTO AntibodyPhospho-FOXO3A (Ser253) AntibodyFOXO1 AntibodyATG10 AntibodyGranulin Antibody (YA1162)ATG13 Antibody (YA1650)ATG9A Antibody (YA3081)LAMP2 Antibody (YA310)WIPI1 Antibody (YA1721)ATG16L1
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Deferiprone-d3，去铁酮 d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Deferiprone-d3 is the deuterium labeled Deferiprone. Deferiprone is the only orally active iron-chelating agent to be used therapeutically in conditions of transfusional iron overload[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Deferiprone-d3 相关抗体:Ferritin Heavy Chain AntibodyCyclophilin A AntibodyCyclophilin B Antibody (YA787)AMID/FSP1 AntibodyPeroxiredoxin 1 Antibody (YA692)PRDX3 Antibody (YA909)Ferritin Light Chain Antibody (YA971)Ferritin Light Chain Antibody (YA972)分子量：142.17Formula：C7H6D3NO2CAS 号：1346601-82-8非标记 CAS：30652-11-0性状：固体颜色：Off-white to light yellow中文名称：去铁酮 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： 99.46%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Kontoghiorghes GJ, et al. Benefits and risks of deferiprone in iron overload in Thalassaemia and other conditions: comparison of epidemiological and therapeutic aspects with deferoxamine. Drug Saf. 2003;26(8):553-584. [Content Brief]
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Piroxicam-d3，吡罗昔康 D3; CP-16171 d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Piroxicam-d3 is deuterium labeled Piroxicam. Piroxicam is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively [1].分子量：334.36Formula：C15H10D3N3O4SCAS 号：942047-64-5非标记 CAS：36322-90-4性状：固体颜色：Light yellow to yellow中文名称：吡罗昔康 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Albendazole-d3，阿苯哒唑-D3; SKF-62979-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Albendazole-d3 is the deuterium labeled Albendazole, which is a member of the benzimidazole compounds used as a agent indicated for the treatment of a variety of worm infestations[1].分子量：268.35Formula：C12H12D3N3O2SCAS 号：1353867-92-1非标记 CAS：54965-21-8性状：固体颜色：White to off-white中文名称：阿苯达唑 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Loperamide-d6 hydrochloride，R-18553-d6 hydrochloride「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Loperamide-d6 (hydrochloride) is a deuterium labeled Loperamide hydrochloride. Loperamide hydrochloride is an opioid receptor agonist for the treatment of diarrhea[1].分子量：519.54Formula：C29H28D6Cl2N2O2CAS 号：1189469-46-2非标记 CAS：34552-83-5性状：固体颜色：White to off-white中文名称：盐酸洛哌丁胺 d6 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Phenindione-d5，苯茚二酮 D5; Rectadione d5「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Phenindione-d5 is deuterium labeled Phenindione, which is an anticoagulant which functions as a Vitamin K antagonist.分子量：227.27Formula：C15H5D5O2CAS 号：70711-53-4非标记 CAS：83-12-5性状：固体颜色：White to off-white中文名称：苯茚二酮 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Enalaprilat-d5 sodium，依那普利拉钠 D5; MK-422-d5 sodium「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Enalaprilat-d5 (sodium) is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor.分子量：397.39Formula：C18H17D5N2Na2O5CAS 号：1356922-29-6性状：固体颜色：White to off-white中文名称：依那普利拉钠 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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(Rac-Ropivacaine-d7，罗哌卡因 d7「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：(Rac)-Ropivacaine-d7 is the deuterium labeled (Rac)-Ropivacaine[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(Rac)-Ropivacaine-d7 相关抗体:xCT Antibody (YA006)xCT Antibody (YA652)ATP1A1 AntibodyAlpha-ENaC AntibodyLGI1 Antibody (YA2885)CRMP2 Antibody (YA3370)SLC12A1 Antibody (YA1403)CRMP1 Antibody (YA1941)Cardiac Troponin C Antibody (YA2125)CRMP5 Antibody (YA2497)CRMP3 Antibody (YA2563)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)CRMP4 Antibody (YA2777)Kir2.1 Antibody (YA2871)分子量：281.44Formula：C17H19D7N2OCAS 号：1392208-04-6非标记 CAS：84057-95-4中文名称：罗哌卡因 d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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Clomifene-d5 hydrochloride，Clomiphene-d5 (hydrochloride「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Clomifene-d5 (hydrochloride) is a deuterium labeled Clomifene. Clomifene is an orally active compound used for infertility. Clomifene is a simple, relatively safe, easily administered and well-tolerated efficacious compound to induce ovulation[1].分子量：447.45Formula：C26H24D5Cl2NOCAS 号：1346606-66-3非标记 CAS：911-45-5性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度： 98.53%参考文献[1]. Wilkes S, et al. Ovulation induction with clomifene: a primary care perspective. J Fam Plann Reprod Health Care. 2012;38(1):48-52. [Content Brief]
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Zuclomiphene-d4 citrate「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Zuclomiphene-d4 (citrate) is a deuterium labeled Zuclomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent[1][2][3][4].分子量：602.11Formula：C32H32D4ClNO8CAS 号：2714316-71-7非标记 CAS：7619-53-6性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Ivabradine-d6 hydrochloride，盐酸伊伐布雷定 D6「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Ivabradine-d6 (hydrochloride) is the deuterium labeled Ivabradine hydrochloride. Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent.分子量：511.08Formula：C27H31D6ClN2O5CAS 号：2070009-63-9非标记 CAS：148849-67-6性状：固体颜色：White to off-white中文名称：盐酸伊伐布雷定 d6 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Pentoxifylline-d5，BL-191-d5; PTX-d5; Oxpentifylline-d5「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-08-13
生物活性：Pentoxifylline-d5 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pentoxifylline-d5 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)PDE1B Antibody (YA1553)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)PDE4D Antibody (YA1714)Tat SF1 Antibody (YA2886)分子量：283.34Formula：C13H13D5N4O3CAS 号：1185995-18-9非标记 CAS：6493-05-6性状：固体颜色：White to off-white中文名称：己酮可可碱 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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