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Amoxicillin-d4,Amoxycillin d4「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Amoxicillin-d4 is a deuterium labeled Amoxicillin. Amoxicillin is an antibiotic with good oral absorption and broad spectrum antimicrobial activity[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Amoxicillin-d4 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量:369.43Formula:C16H15D4N3O5SCAS 号:2673270-36-3非标记 CAS:26787-78-0性状:固体颜色:White to off-white中文名称:阿莫西林钠 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month
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Salicylic acid-13C6,2-Hydroxybenzoic acid-13C6「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Salicylic acid-13C6 is the 13C-labeled Salicylic acid (HY-B0167). Salicylic acid is a precursor to and a metabolite of Aspirin.html" class="link-product" target="_blank">Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Salicylic acid-13C6 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyMETTL3 Antibodyc-Myc AntibodyCyclin E1 AntibodyTSG101 AntibodyAIF Antibody (YA636)ALIX AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)CNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 Antibody分子量:144.08Formula:C13C6H6O3CAS 号:1189678-81-6非标记 CAS:69-72-7性状:固体颜色:Off-white to light yellow中文名称:水杨酸 13C6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month
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Entacapone-d10,恩他卡朋 d10「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Entacapone-d10 is the deuterium labeled Entacapone. Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 µM). Entacapone can be used for the research of Parkinson's disease[1]. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders[2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:315.35Formula:C14H5D10N3O5CAS 号:1185241-19-3非标记 CAS:130929-57-6性状:固体颜色:Yellow to brown中文名称:恩他卡朋 d10运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Thiocolchicine-d3「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Thiocolchicine-d3 is deuterium labeled Thiocolchicine. Thiocolchicine, a derivative modified in the C Ring of Colchicine (HY-16569) with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization (IC50=2.5 µM) and competitively binds to tubulin with a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis[1][2]. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Thiocolchicine-d3 相关抗体:ERK1/2 Antibodyalpha Tubulin AntibodyLC3A/B AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyBeta Tubulin Antibodyc-Myc AntibodyCyclin E1 Antibodybeta Tubulin Antibody (YA839)AIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)Doublecortin AntibodyDR5 AntibodyDrosha Antibody分子量:418.52Formula:C22H22D3NO5SCAS 号:1314417-95-2非标记 CAS:2730-71-4性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Prasugrel-d3,PCR 4099-d3「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Prasugrel-d3 is the deuterium labeled Prasugrel. Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1].IC50 & Target:P2Y12 Receptor体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Prasugrel-d3 相关抗体:P2Y12 Antibody (YA3135)P2Y6 Antibody (YA1691)分子量:376.46Formula:C20H17D3FNO3SCAS 号:1127253-02-4非标记 CAS:150322-43-3性状:固体颜色:White to off-white中文名称:普拉格雷 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month
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Levofloxacin-d8 hydrochloride,盐酸左氧氟沙星-d8「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Levofloxacin-d8 (hydrochloride) is deuterium labeled Levofloxacin (hydrochloride).体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:405.88Formula:C18H13D8ClFN3O4CAS 号:2699607-50-4非标记 CAS:177325-13-2性状:固体颜色:White to off-white中文名称:盐酸左氧氟沙星-d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度: ≥99.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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Prostaglandin D2-d9,PGD2-d9「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Prostaglandin D2-d9 is the deuterium labeled Prostaglandin D2. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals[1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances[2]. PGD2 plays a protective role by suppressing inflammation[3].IC50 & Target:DP体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Prostaglandin D2-d9 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:361.52Formula:C20H23D9O5CAS 号:2254642-52-7非标记 CAS:41598-07-6性状:液体颜色:Colorless to light yellow运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Solution, -20°C, 2 years
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Ambroxol-d5 hydrochloride,NA-872-d5 hydrochloride「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Ambroxol-d5 (hydrochloride) is the deuterium labeled Ambroxol hydrochloride. Ambroxol hydrochloride (NA-872 hydrochloride), an active metabolite of the proagent Bromhexine, has potent expectorant effects. Ambroxol hydrochloride is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol hydrochloride induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ambroxol-d5 hydrochloride 相关抗体:Glucosidase 2 subunit beta AntibodyKlotho Antibody (YA3355)GAA Antibody (YA2872)分子量:419.59Formula:C13H14D5Br2ClN2OCAS 号:2741380-71-0非标记 CAS:23828-92-4性状:固体颜色:White to off-white中文名称:盐酸氨溴索 d5 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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3-Methylxanthine-13C4,15N3「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:3-Methylxanthine-13C4,15N3 is the 13C-labeled and 15N-labeled 3-Methylxanthine. 3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.3-Methylxanthine-13C4,15N3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:173.09Formula:C213C4H6N15N3O2CAS 号:1173018-93-3非标记 CAS:1076-22-8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (544 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2)
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Montelukast-d6 sodium,MK0476-d6「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Montelukast-d6 (sodium) is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage[1].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Montelukast-d6 sodium 相关抗体:Leukotriene A4 Hydrolase Antibody (YA2400)分子量:614.20Formula:C35H29D6ClNNaO3SCAS 号:2673270-26-1非标记 CAS:151767-02-1性状:固体颜色:White to off-white中文名称:孟鲁司特钠 d6 (钠盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度: ≥96.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Pu S, et, al. Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury. Front Pharmacol. 2019 Sep 18; 10:1070.;William RHJ, et, al. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am J Respir Crit Care Med. 2002 Jan 1; 165(1): 108-16. [Content Brief]
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β-Caryophyllene-d2,β-石竹烯-d2「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:β-Caryophyllene-d2 is deuterium labeled β-Caryophyllene. β-Caryophyllene is a CB2 receptor agonist.体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.β-Caryophyllene-d2 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:206.36Formula:C15H22D2CAS 号:2006272-96-2非标记 CAS:87-44-5性状:油状物颜色:Colorless to light yellow中文名称:β-石竹烯-d2;β-丁香烯-d2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Filgotinib-d4,GLPG0634-d4「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Filgotinib-d4 is the deuterium labeled Filgotinib. Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Filgotinib-d4 相关抗体:Phospho-JAK2 (Tyr1007/1008) AntibodyJAK1 Antibody (YA722)JAK1 AntibodyJAK2 Antibody (YA721)Phospho-JAK2 (Tyr1007+Tyr1008) AntibodyJAK2 Antibody (YA330)Phospho-JNK (Thr183) AntibodyJAK3 Antibody (YA2466)分子量:429.53Formula:C21H19D4N5O3SCAS 号:2041095-50-3非标记 CAS:1206161-97-8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Van Rompaey L, et al. Preclinical characterization of GLPG0634, a selective inhibitor of JAK1, for the treatment of inflammatory diseases. J Immunol. 2013, 191(7), 3568-3577. [Content Brief][3]. Menet CJ, et al. Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634. J Med Chem. 2014 Nov 17. [Content Brief]
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Bambuterol-d9 hydrochloride,班布特罗-d9; (±-Bambuterol-d9 hydrochloride; KWD-2183-d9 hydrochloride「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Bambuterol-d9 (hydrochloride) is the deuterium labeled Bambuterol. Bambuterol ((±)-Bambuterol) hydrochloride is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Bambuterol-d9 hydrochloride 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量:412.96Formula:C18H21D9ClN3O5CAS 号:1794810-59-5非标记 CAS:81732-65-2性状:固体颜色:White to off-white中文名称:班布特罗盐酸盐-d9运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Taurodeoxycholate-d6 sodium salt,牛磺脱氧胆酸钠-d6「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Taurodeoxycholate-d6 sodium salt is a bile salt-related anionic detergent. Taurodeoxycholate-d6 sodium salt is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate-d6 sodium salt is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate-d6 (TDCA) exhibits anti-inflammatory and neuroprotective effects[1][2][3][9][10].体外研究(In Vitro):Taurodeoxycholate-d6 sodium salt (Taurodeoxycholic acid form) 通过荧光素酶检测,对 CHO 细胞中表达的人 TGR5 具有激动活性,EC50 为 0.79 μM[4]。Taurodeoxycholate-d6 sodium salt (Taurodeoxycholic acid form, 16 h) 对在 HEK293 细胞中表达的野生型和 Y89A 突变型人 TGR5 具有激动剂活性,其 EC50 分别为 0.68 和 8.9 μM (以细胞内 cAMP 水平的升高来评估)[5]。Taurodeoxycholate-d6 sodium salt (Taurodeoxycholic acid form, 50-100 μM,4 h) 增加原代人肝细胞中寡核体 DNA 切割和细胞核凋亡[6]。Taurodeoxycholate-d6 sodium salt (Taurodeoxycholic acid form, 400 μM,18-24 h) 在人肝来源的 Huh7 细胞中增加 DNA 碎片和 PARP 切割,诱导凋亡[7]。Taurodeoxycholate-d6 (0.05-1.00 mM,1-6 天) sodium salt 刺激肠上皮细胞增殖[8]。Taurodeoxycholate-d6 (0.05-1.00 mM,24 h) sodium salt 诱导细胞周期的S期浓度显著增加和 G1 期浓度显著降低,增加c-myc IEC-6细胞蛋白和 mRNA 的表达[8]。Taurodeoxycholate-d6 (25-400 ng/mL,稀释四倍,3 h) sodium salt 通过激活 cAMP-PKA 轴,抑制脂多糖激活的骨髓源性巨噬细胞 (BMDMs) 中 NF-κB 的活化[9]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Taurodeoxycholate-d6 sodium salt 相关抗体:BNSP AntibodyFACL4 AntibodyB
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Sodium borodeuteride-d4「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Sodium borodeuteride-d4 is the deuterium labeled Sodium borodeuteride[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Sodium borodeuteride-d4 相关抗体:CD161 AntibodyBrdU Antibody (YA578)CD99 AntibodyCD44 AntibodyDYKDDDDK Tag (FLAG) AntibodyGFP AntibodyMyc-tag AntibodyFerritin Heavy Chain Antibody53BP1 AntibodyCD9 Antibody (YA524)METTL3 AntibodyNeuN Antibodyp27 KIP 1 AntibodyUbiquitin Antibody (YA022)Beta Tubulin AntibodySQSTM1/p62 Antibody (YA669)TGF beta 1 AntibodyCD45 Antibody (YA800)CD63 AntibodyCD81 AntibodyCD86 AntibodyCD9 Antibodyp38 AntibodySQSTM1/p62 Antibody (YA062)xCT Antibody (YA006)CD40 AntibodyCD40L AntibodyCD42a AntibodyCD45 Antibody (YA533)CD47 Antibody分子量:41.86Formula:BD4NaCAS 号:15681-89-7非标记 CAS:16940-66-2性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Store at room temperature, keep dry and coolIn solvent:-80°C:2 years-20°C:1 year纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]