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「同位素标记抑制剂」CAS:2747918-62-1|(Rac)-Tolterodine-d5
作者：德尔塔生物 日期：2025-06-13
生物活性：(Rac)-Tolterodine-d5 is deuterium labeled (rac)-Tolterodine.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(Rac)-Tolterodine-d5 相关抗体:Muscarinic Acetylcholine receptor M3 AntibodyMuscarinic Acetylcholine Receptor M2 Antibody (YA2610)分子量：330.52Formula：C22H26D5NOCAS 号：2747918-62-1非标记 CAS：124936-74-9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」CAS:1356840-08-8|Moexiprilat-d5
作者：德尔塔生物 日期：2025-06-13
生物活性：Moexiprilat-d5 is deuterium labeled Moexiprilat.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：475.55Formula：C25H25D5N2O7CAS 号：1356840-08-8非标记 CAS：103775-14-0运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (518 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」CAS:1185242-27-6|Cinnarizine-d8
作者：德尔塔生物 日期：2025-06-13
生物活性：Cinnarizine-d8 is a deuterium labeled Cinnarizine. Cinnarizine is an antihistamine and a calcium channel blocker.分子量：376.56Formula：C26H20D8N2CAS 号：1185242-27-6非标记 CAS：298-57-7性状：固体颜色：Light yellow to yellow中文名称：桂利嗪 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1185878-98-1|Pentoxifylline-d6
作者：德尔塔生物 日期：2025-06-13
生物活性：Pentoxifylline-d6 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pentoxifylline-d6 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)PDE1B Antibody (YA1553)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)PDE4D Antibody (YA1714)Tat SF1 Antibody (YA2886)分子量：284.34Formula：C13H12D6N4O3CAS 号：1185878-98-1非标记 CAS：6493-05-6性状：固体颜色：White to off-white中文名称：己酮可可碱 d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:2122830-90-2|Flibanserin-d4
作者：德尔塔生物 日期：2025-06-13
生物活性：Flibanserin-d4 is a deuterium labeled Flibanserin (BIMT-17). Flibanserin is a full agonist of the serotonin 5-HT1A receptor (Ki=1 nM) and an antagonist of 5-HT2A (49 nM)[1].分子量：394.43Formula：C20H17D4F3N4OCAS 号：2122830-90-2非标记 CAS：167933-07-5中文名称：氟立班丝氨 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Invernizzi RW, et al. Flibanserin, a potential antidepressant drug, lowers 5-HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: role of 5-HT(1A) receptors. Br J Pharmacol. 2003 Aug;139(7):1281-8. [Content Brief]
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「同位素标记抑制剂」CAS:2375858-08-3|Pyridostigmine-d6 bromide
作者：德尔塔生物 日期：2025-06-13
生物活性：Pyridostigmine-d6 (bromide) is the deuterium labeled Pyridostigmine, which is a parasympathomimetic and a reversible cholinesterase inhibitor.分子量：267.15Formula：C9H7D6BrN2O2CAS 号：2375858-08-3非标记 CAS：101-26-8性状：固体颜色：White to light yellow中文名称：溴化吡啶斯的明 d6 (溴盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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「同位素标记抑制剂」CAS:2122245-62-7|Abiraterone-d4
作者：德尔塔生物 日期：2025-06-13
生物活性：Abiraterone-d4 is the deuterium labeled Abiraterone. Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Abiraterone-d4 相关抗体:Cytochrome C AntibodyCytochrome P450 17A1 AntibodyAromatase AntibodyCYP11A1 AntibodyCytochrome P450 1B1 Antibody (YA1836)Adrenodoxin Antibody (YA2005)Cytochrome P450 27A1 Antibody (YA2163)Cytochrome P450 2C9 Antibody (YA2166)Cytochrome P450 2E1 Antibody (YA2302)Cytochrome P450 Reductase Antibody (YA2619)Thromboxane A Synthase Antibody (YA2670)Cytochrome P450 3A4 Antibody (YA3365)HSD11B1 Antibody (YA3376)Cytochrome P450 17A1 Antibody (YA786)CYP2E1 AntibodyCYP1A2 AntibodyPLSCR3 Antibody (YA1672)PROX1 Antibody (YA1754)Cytochrome P450 4A Antibody (YA2087)Cytochrome P450 24A1 Antibody (YA2121)Cytochrome P450 26A1 Antibody (YA2259)COX5B Antibody (YA2550)Steroidogenic Factor 1 Antibody (YA3166)Dynein Light Chain Tctex Type 1 Antibody (YA3263)Cytochrome P450 2D6 Antibody (YA3384)分子量：353.53Formula：C24H27D4NOCAS 号：2122245-62-7非标记 CAS：154229-19
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「同位素标记抑制剂」CAS:1219798-89-6|Hydrochlorothiazid-d2
作者：德尔塔生物 日期：2025-06-13
生物活性：Hydrochlorothiazid-d2 is the deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Hydrochlorothiazid-d2 相关抗体:Smad3 AntibodyTGF beta 1 AntibodySmad1 AntibodySmad2 AntibodySmad4 AntibodySmad5 AntibodyPhospho-Smad3 (Ser423/Ser425) AntibodyATP1A1 AntibodyCD105 Antibody (YA547)Noggin Antibody (YA698)Phospho-Smad1 (Ser463/Ser465) AntibodyPhospho-Smad2 (Ser250) AntibodyPhospho-Smad3 (Ser423/425) AntibodySmad2/3 AntibodyInhibin beta A Antibody (YA2780)Phospho-Smad5 (Ser463/465) Antibody (YA2838)LGI1 Antibody (YA2885)Inhibin alpha Antibody (YA1232)Inhibin beta B Antibody (YA1677)Cardiac Troponin C Antibody (YA2125)Phospho-NDRG1 (Ser330) Antibody (YA2618)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)Kir2.1 Antibody (YA2871)SARA Antibody (YA3226)分子量：299.75Formula：C7H6D2ClN3O4S2CAS 号：1219798-89-6非
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「同位素标记抑制剂」CAS:1035437-39-8|Alendronic acid-d6
作者：德尔塔生物 日期：2025-06-13
生物活性：Alendronic acid-d6 is the deuterium labeled Alendronic acid. Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Paget’s disease[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：255.13Formula：C4H7D6NO7P2CAS 号：1035437-39-8非标记 CAS：66376-36-1性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:934295-48-4|Rabeprazole-d4
作者：德尔塔生物 日期：2025-06-13
生物活性：Rabeprazole-d4 is a deuterium labeled Rabeprazole. Rabeprazole is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].IC50 & Target：Pump inhibitor (PPI); UNH[1]H+/K+-ATPase; Apoptosis[2]分子量：363.47Formula：C18H17D4N3O3SCAS 号：934295-48-4非标记 CAS：117976-89-3性状：固体颜色：White to light brown中文名称：雷贝拉唑 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1020719-98-5|Triclosan-d3
作者：德尔塔生物 日期：2025-06-13
生物活性：Triclosan-d3 is the deuterium labeled Triclosan. Triclosan is an antibacterial and antifungal agent found in consumer products, including soaps, detergents, toys, and surgical cleaning treatments[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Triclosan-d3 相关抗体:SDHA AntibodyMRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：292.56Formula：C12H4D3Cl3O2CAS 号：1020719-98-5非标记 CAS：3380-34-5性状：固体颜色：White to off-white中文名称：三氯生 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:117490-39-8|Theophylline-d6
作者：德尔塔生物 日期：2025-06-13
生物活性：Theophylline-d6 is the deuterium labeled Theophylline. Theophylline is a nonselective phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Theophylline-d6 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：186.20Formula：C7H2D6N4O2CAS 号：117490-39-8非标记 CAS：58-55-9性状：固体颜色：White to off-white中文名称：茶碱 d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1219795-16-0|Diphenhydramine-d5 hydrochloride
作者：德尔塔生物 日期：2025-06-13
生物活性：Diphenhydramine-d5 (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Diphenhydramine-d5 hydrochloride 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyADGRE1 (F4/80) Antibody (YA002)TSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 Antibody分子量：296.85Formula：C17H17D5ClNOCAS 号：1219795-16-0非标记 CAS：147-24-0性状：固体颜色：White to off-white中文名称：盐酸苯海拉明 d5 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储
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「同位素标记抑制剂」CAS:1189959-13-4|Lidocaine-d10 hydrochloride
作者：德尔塔生物 日期：2025-06-13
生物活性：Lidocaine-d10 (hydrochloride) is the deuterium labeled Lidocaine hydrochloride. Lidocaine hydrochloride (Lignocaine hydrochloride) inhibits sodium channels involving complex voltage and using dependence[1]. Lidocaine hydrochloride decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine hydrochloride, an amide derivative, has the potential for the research of the ventricular arrhythmia[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Lidocaine-d10 hydrochloride 相关抗体:MEK1/2 AntibodyERK1/2 AntibodyPhospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) AntibodyNF-KB p65 AntibodyPhospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Antibody (YA455)Phospho-NF-KB p65 (Ser536) AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyPhospho-NF-κB p65 (Ser529) AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyNF-KB p65 Antibody (YA267)ERK2 Antibodyc-Myc AntibodyCyclin E1 AntibodyPhospho-MEK1 (Ser298) AntibodyxCT Antibody (YA006)AI
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「同位素标记抑制剂」CAS:940867-25-4|Docetaxel-d9
作者：德尔塔生物 日期：2025-06-13
生物活性：Docetaxel-d9 is the deuterium labeled Docetaxel. Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer activity[1][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Docetaxel-d9 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)ERK1/2 Antibodyalpha Tubulin AntibodyLC3A/B AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyMETTL3 AntibodyBeta Tubulin Antibodyc-Myc AntibodyCyclin E1 AntibodyTSG101 Antibodybeta Tubulin Antibody (YA839)AIF Antibody (YA636)ALIX AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)CNPase Antibody分子量：816.93Formula：C43H44D9NO14CAS 号：940867-25-4非标记 CAS：114977-28-5性状：固体颜色：White to off-white中文名称：多西他赛 d9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder
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