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CAS:2699608-28-9|O-Desmethyl Midostaurin-d5,CGP62221-d5; O-Desmethyl PKC412-d5

CAS:2699608-28-9|O-Desmethyl Midostaurin-d5,CGP62221-d5; O-Desmethyl PKC412-d5

作者:德尔塔生物 日期:2025-08-13

生物活性:O-Desmethyl Midostaurin-d5 is a deuterium labeled O-Desmethyl PKC412. O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism[1].IC50 & Target:IC50: active metabolite of Midostaurin[1]分子量:561.64Formula:C34H23D5N4O4CAS 号:2699608-28-9非标记 CAS:740816-86-8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Levis M, et al. Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors. Blood. 2006 Nov 15;108(10):3477-83. [Content Brief]

CAS:250608-66-3|Sulindac sulfide-d3,cis-Sulindac sulfide-d3

CAS:250608-66-3|Sulindac sulfide-d3,cis-Sulindac sulfide-d3

作者:德尔塔生物 日期:2025-08-13

生物活性:Sulindac sulfide-d3 is deuterium labeled Sulindac sulfide. Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Sulindac sulfide-d3 相关抗体:Presenilin 1 Antibody (YA1722)Nicastrin Antibody (YA1397)Presenilin 2 Antibody (YA1605)Phospho-Presenilin 1 (Ser310) Antibody (YA1868)Phospho-Presenilin 2 (Ser330) Antibody (YA1878)分子量:343.43Formula:C20H14D3FO2SCAS 号:250608-66-3非标记 CAS:49627-27-2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Takahashi Y, et al. Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation. J Biol Chem. 2003 May 16;278(20):18664-70. [Content Brief]

CAS:201996-39-6|Phosphoenolpyruvic acid (potassium-13C2,磷酸烯醇式丙酮酸钾-13C2; Phosphoenolpyruvate (potassium-13C2

CAS:201996-39-6|Phosphoenolpyruvic acid (potassium-13C2,磷酸烯醇式丙酮酸钾-13C2; Phosphoenolpyruvate (potassium-13C2

作者:德尔塔生物 日期:2025-08-13

生物活性:Phosphoenolpyruvic acid (potassium)-13C2 is the 13C labeled Phosphoenolpyruvic acid potassium (HY-W008807)[1]. Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties[2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Phosphoenolpyruvic acid (potassium)-13C2 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:208.12Formula:C13C2H4KO6PCAS 号:201996-39-6非标记 CAS:4265-07-0中文名称:磷酸烯醇式丙酮酸钾-13C2运输条件:Room temperature in continental US; may vary elsewhere.储存

CAS:2446366-95-4|Pyriproxyfen-d4,S-31183-d4

CAS:2446366-95-4|Pyriproxyfen-d4,S-31183-d4

作者:德尔塔生物 日期:2025-08-13

生物活性:Pyriproxyfen-d4 is the deuterium labeled Pyriproxyfen[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:325.39Formula:C20H15D4NO3CAS 号:2446366-95-4非标记 CAS:95737-68-1中文名称:吡丙醚-d4;蚊蝇醚-d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

CAS:2124271-48-1|(--Nebivolol-d4 hydrochloride

CAS:2124271-48-1|(--Nebivolol-d4 hydrochloride

作者:德尔塔生物 日期:2025-08-13

生物活性:(-)-Nebivolol-d4 (hydrochloride) is the deuterium labeled (-)-Nebivolol hydrochloride[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:445.92Formula:C22H22D4ClF2NO4CAS 号:2124271-48-1非标记 CAS:152520-56-4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (516 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

CAS:2469274-07-3|3-O-Methyltolcapone-d4,Ro 40-7591-d4

CAS:2469274-07-3|3-O-Methyltolcapone-d4,Ro 40-7591-d4

作者:德尔塔生物 日期:2025-08-13

生物活性:3-O-Methyltolcapone-d4 is the deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:291.29Formula:C15H9D4NO5CAS 号:2469274-07-3非标记 CAS:134612-80-9运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief][2]. Jorga K, et al. Metabolism and excretion of tolcapone, a novel inhibitor of catechol-O-methyltransferase. Br J Clin Pharmacol. 1999 Oct;48(4):513-20. [Content Brief][3]. Ceravolo R, et al. 18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease. Synapse. 2002 Mar 1;43(3):201-7. [Content Brief]

CAS:1210608-86-8|Sorafenib-13C,d3,索拉非尼-13C,d3; Bay 43-9006-13C,d3

CAS:1210608-86-8|Sorafenib-13C,d3,索拉非尼-13C,d3; Bay 43-9006-13C,d3

作者:德尔塔生物 日期:2025-08-13

生物活性:Sorafenib-13C,d3 is the 13C- and deuterium labeled Sorafenib. Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. Sorafenib is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Sorafenib-13C,d3 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyBRAF Antibodyc-Myc AntibodyCyclin E1 AntibodyPhospho-BRAF (Thr401) AntibodyAIF Antibody (YA636)ALIX AntibodyA-RAF AntibodyB-Raf AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)分子量:468.84Formula:C2013CH13D3ClF3N4O3CAS 号:1210608-86-8非标记 CAS:284461-73-0性状:固体颜色:

CAS:1538624-35-9|Carbamazepine-d8,卡马西平-d8; CBZ-d8; NSC 169864-d8

CAS:1538624-35-9|Carbamazepine-d8,卡马西平-d8; CBZ-d8; NSC 169864-d8

作者:德尔塔生物 日期:2025-08-13

生物活性:Carbamazepine-d8 is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent, with an IC50 of 131 μM[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Carbamazepine-d8 相关抗体:xCT Antibody (YA006)xCT Antibody (YA652)Alpha-ENaC AntibodyCRMP2 Antibody (YA3370)SLC12A1 Antibody (YA1403)CRMP1 Antibody (YA1941)CRMP5 Antibody (YA2497)CRMP3 Antibody (YA2563)CRMP4 Antibody (YA2777)分子量:244.32Formula:C15H4D8N2OCAS 号:1538624-35-9非标记 CAS:298-46-4性状:固体颜色:Off-white to light yellow中文名称:卡马西平-d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 98.70%参考文献[1]. Willow, M. and W.A. Catterall, Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine. Mol Pharmacol, 1982. 22(3): p. 627-35. [Content Brief][2]. Okada, M., et al., Biphasic effects of carbamazepine on the dopaminergic system in rat striatum and hippocampus. Epilepsy Res, 1997. 28(2): p. 143-53. [Content Brief][3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

CAS:326495-30-1|Colfosceril miristate-d63,DMPC-d63;  1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d63

CAS:326495-30-1|Colfosceril miristate-d63,DMPC-d63; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d63

作者:德尔塔生物 日期:2025-08-13

生物活性:Colfosceril miristate-d63 (DMPC-d63) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:741.32Formula:C36H9D63NO8PCAS 号:326495-30-1非标记 CAS:18194-24-6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (533 KB)产品使用指南 (1538 KB)参考文献[1]. Iwona Budziak, et al. Effect of polyols on the DMPC lipid monolayers and bilayers. Biochim Biophys Acta Biomembr. 2018 Nov;1860(11):2166-2174. [Content Brief][2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

CAS:326495-28-7|Colfosceril miristate-d13,DMPC-d13;  1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d13

CAS:326495-28-7|Colfosceril miristate-d13,DMPC-d13; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d13

作者:德尔塔生物 日期:2025-08-13

生物活性:Colfosceril miristate-d13 (DMPC-d13) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:691.01Formula:C36H59D13NO8PCAS 号:326495-28-7非标记 CAS:18194-24-6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Iwona Budziak, et al. Effect of polyols on the DMPC lipid monolayers and bilayers. Biochim Biophys Acta Biomembr. 2018 Nov;1860(11):2166-2174. [Content Brief][2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

CAS:1210608-88-0|Dabigatran-13C6,BIBR 953-13C6; BIBR 953ZW-13C6

CAS:1210608-88-0|Dabigatran-13C6,BIBR 953-13C6; BIBR 953ZW-13C6

作者:德尔塔生物 日期:2025-07-08

生物活性:Dabigatran-13C6 is the 13C labeled Dabigatran[1]. Dabigatran (BIBR 953), an oral anticoagulant, is a reversible, potent, competitive direct thrombin inhibitor (Ki=4.5 nM). Dabigatran (BIBR 953) also inhibits thrombin-induced platelet aggregation (IC50=10 nM)[2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Dabigatran-13C6 相关抗体:PAR2 Antibody (YA2455)Protein C Antibody (YA2461)Thrombomodulin Antibody (YA891)Thrombomodulin Antibody (YA892)F2 AntibodyPAR6 Antibody (YA1536)Prothrombin Antibody (YA1753)PAR4 Antibody (YA2603)Protein S Antibody (YA2919)分子量:477.47Formula:C1913C6H25N7O3CAS 号:1210608-88-0非标记 CAS:211914-51-1中文名称:达比加群-13C6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Wienen W, Stassen JM, Priepke H, In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally activeprodrug, da

CAS:1204192-90-4|Ibudilast-d7-1,异丁司特-d7-1; KC-404-d7-1; AV-411-d7-1; MN-166-d7-1

CAS:1204192-90-4|Ibudilast-d7-1,异丁司特-d7-1; KC-404-d7-1; AV-411-d7-1; MN-166-d7-1

作者:德尔塔生物 日期:2025-07-08

生物活性:Ibudilast-d7-1 is the deuterium labeled Ibudilast[1]. Ibudilast (KC-404;AV-411;MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ibudilast-d7-1 相关抗体:PDE1B Antibody (YA1553)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)PDE4D Antibody (YA1714)分子量:237.35Formula:C14H11D7N2OCAS 号:1204192-90-4非标记 CAS:50847-11-5中文名称:异丁司特-d7-1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (539 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Mizuno T, et al. Neuroprotective role of phosphodiesterase inhibitor ibudilast on neuronal cell death induced by activated microglia. Neu

CAS:1795132-80-7|Zuclomiphene-d5 citrate

CAS:1795132-80-7|Zuclomiphene-d5 citrate

作者:德尔塔生物 日期:2025-07-08

生物活性:Zuclomiphene-d5 (citrate) is the deuterium labeled Zuclomiphene citrate[1]. Zuclomiphene citrate is a cis isomer of Clomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent[2][3][4][5].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Zuclomiphene-d5 citrate 相关抗体:Estrogen Receptor alpha Antibody (YA768)Estrogen Receptor alpha AntibodyGPR30 AntibodyPBR Antibody (YA1785)REA Antibody (YA1848)Estrogen Related Receptor gamma Antibody (YA2009)ERR alpha Antibody (YA2283)Estrogen Receptor beta Antibody (YA1892)14-3-3 Antibody (YA1949)Estrogen Inducible Protein pS2 Antibody (YA2377)MVK Antibody (YA3093)分子量:603.11Formula:C32H31D5ClNO8CAS 号:1795132-80-7非标记 CAS:7619-53-6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (534 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):21

CAS:1073244-89-9|(Rac-Normetanephrine-d3

CAS:1073244-89-9|(Rac-Normetanephrine-d3

作者:德尔塔生物 日期:2025-07-08

生物活性:(Rac)-Normetanephrine-d3 is the deuterium labeled (Rac)-Normetanephrine[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:186.22Formula:C9H10D3NO3CAS 号:1073244-89-9非标记 CAS:97-31-4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

CAS:1216796-18-7|Amiloride-15N3 hydrochloride,MK-870-15N3 hydrochloride

CAS:1216796-18-7|Amiloride-15N3 hydrochloride,MK-870-15N3 hydrochloride

作者:德尔塔生物 日期:2025-07-08

生物活性:Amiloride-15N3 (hydrochloride) is the 15N labeled Amiloride hydrochloride[1]. Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel (ENaC[2]) and urokinase-type plasminogen activator receptor (uTPA[3]). Amiloride hydrochloride is a blocker of polycystin-2 (PC2;TRPP2[4]) channel.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Amiloride-15N3 hydrochloride 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyxCT Antibody (YA006)AIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase Antibody分子量:269.07Formula:C6H9Cl2N415N3OCAS 号:1216796-18-7非标记 CAS:2016-88-8中文名称:盐酸阿米洛利-15N3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under th