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CAS:203784-52-5|Nortriptyline-d3 hydrochloride，Desmethylamitriptyline-d3 (hydrochloride; Desitriptilina-d3 (hydrochloride
作者：德尔塔生物 日期：2025-07-08
生物活性：Nortriptyline-d3 (hydrochloride) is the deuterium labeled Nortriptyline hydrochloride. Nortriptyline hydrochloride (Desmethylamitriptyline hydrochloride) is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and used to relieve the symptoms of depression[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nortriptyline-d3 hydrochloride 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量：302.86Formula：C19H19D3ClNCAS 号：203784-52-5非标记 CAS：894-71-3性状：固体颜色：White to off-white中文名称：盐酸去甲替林 d3 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture
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CAS:64717-35-7|Propantheline-d3 bromide，普鲁本辛 d3 (溴盐
作者：德尔塔生物 日期：2025-07-08
生物活性：Propantheline-d3 (bromide) is the deuterium labeled Propantheline bromide. Propantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Propantheline-d3 bromide 相关抗体:Muscarinic Acetylcholine receptor M3 AntibodyMuscarinic Acetylcholine Receptor M2 Antibody (YA2610)分子量：451.41Formula：C23H27D3BrNO3CAS 号：64717-35-7非标记 CAS：50-34-0性状：固体颜色：Off-white to light yellow中文名称：普鲁本辛 d3 (溴盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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CAS:1185117-79-6|Climbazole-d4，BAY-e 6975-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Climbazole-d4 is the deuterium labeled Climbazole. Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Climbazole-d4 相关抗体:SDHA Antibody分子量：296.79Formula：C15H13D4ClN2O2CAS 号：1185117-79-6非标记 CAS：38083-17-9性状：固体颜色：White to off-white中文名称：氯咪巴唑 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:94513-92-5|Nadolol-d9，纳多洛尔 D9; SQ-11725-d9
作者：德尔塔生物 日期：2025-07-08
生物活性：Nadolol-d9 is the deuterium labeled Nadolol. Nadolol is a non-selective and orally active β-adrenergic receptors blocker[1].分子量：318.46Formula：C17H18D9NO4CAS 号：94513-92-5非标记 CAS：42200-33-9性状：固体颜色：Off-white to light yellow中文名称：纳多洛尔 d9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1185039-30-8|Gliclazide-d4，格列齐特 d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Gliclazide-d4 (S1702 D4) is the deuterium labeled Gliclazide. Gliclazide (S1702) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Gliclazide is used as an antidiabetic[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Gliclazide-d4 相关抗体:ATP1A1 AntibodyLGI1 Antibody (YA2885)Cardiac Troponin C Antibody (YA2125)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)Kir2.1 Antibody (YA2871)分子量：327.44Formula：C15H17D4N3O3SCAS 号：1185039-30-8非标记 CAS：21187-98-4性状：固体颜色：White to off-white中文名称：格列齐特 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:85806-18-4|delta-Valerobetaine-d9 chloride
作者：德尔塔生物 日期：2025-07-08
生物活性：delta-Valerobetaine-d9 chloride is the deuterium labeled delta-Valerobetaine (HY-114202)[1]. delta-Valerobetaine is a precursor of trimethylamine N-oxide (TMAO)[2].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.delta-Valerobetaine-d9 chloride 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：204.74Formula：C8H9D9ClNO2CAS 号：85806-18-4非标记 CAS：6778-33-2性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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CAS:1356019-94-7|Levomefolic acid-13C,d3，5-甲基四氢叶酸-13C,d3; L-5-MTHF-13C,d3
作者：德尔塔生物 日期：2025-07-08
生物活性：Levomefolic acid-13C,d3 is the deuterium labeled Levomefolic acid (HY-14781)[1]. Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[2][3].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Levomefolic acid-13C,d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCtip2 AntibodyMETTL3 AntibodyRb AntibodyPhospho-Rb (Ser807) AntibodyTSG101 AntibodyRPA32 Antibody (YA679)Alkaline Phosphatase AntibodyCalnexin Antibody (YA573)Catalase Antibody (YA552)Catalase Antibody (YA811)CDT1 AntibodyDNA-PKcs/PRKDC AntibodyHes1 AntibodyJunB AntibodyLamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyLIN28A AntibodyLin28B AntibodyMCM2 AntibodyNanog AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)分子量：463.47Formula：C1913CH22D3N7O6CAS 号：1356019-94-7非标记 CAS：31690-09-2性状：固体颜色：White to off-white中文名称：5-甲基四氢叶酸-13C,d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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CAS:338976-76-4|3α,7α-Dihydroxycoprostanic acid-d3，3α,7α-二羟基粪烯酸-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：3α,7α-Dihydroxycoprostanic acid-d3 is the deuterium labeled 3α,7α-Dihydroxycoprostanic acid (HY-113097)[1]. 3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid[2].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.3α,7α-Dihydroxycoprostanic acid-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：437.67Formula：C27H43D3O4CAS 号：338976-76-4非标记 CAS：17974-66-2性状：固体颜色：White to off-white中文名称：3α,7α-二羟基粪烯酸-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： ≥99.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharm
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CAS:850153-85-4|DL-dithiothreitol-d6，DTT-d6
作者：德尔塔生物 日期：2025-07-08
生物活性：DL-dithiothreitol-d6 is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：160.29Formula：C4H4D6O2S2CAS 号：850153-85-4非标记 CAS：3483-12-3性状：固体颜色：White to off-white中文名称：DL-二硫苏糖醇-d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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CAS:461426-34-6|N-(4-Aminobenzoyl-L-glutamic acid-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：N-(4-Aminobenzoyl)-L-glutamic acid-d4 is the deuterium labeled 4-Nitrobenzoic acid[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：270.27Formula：C12H10D4N2O5CAS 号：461426-34-6非标记 CAS：4271-30-1性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1219794-66-7|Octanal-d16
作者：德尔塔生物 日期：2025-07-08
生物活性：Octanal-d16 is the deuterium labeled Octanal. Octanal is a fragrant aldehyde with antioxidant and antibacterial activity. Its antifungal effect against G. citri-aurantii may be related to the disruption of cell membrane integrity and the leakage of cellular components. Additionally, Octanal exhibits cytotoxicity towards HeLa cells, with an IC50 value of 3.5 μg/mL[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Octanal-d16 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySDHA AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 Antibody分子量：144.31Formula：C8D16OCAS 号：1219794-66-7非标记 CAS：124-13-0性状：液体颜色：Colorless to light yellow运输条件：Room temperature in continental US; may vary e
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CAS:1020719-89-4|Sulfathiazole-d4，磺胺噻唑-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Sulfathiazole-d4 is a deuterium labeled Sulfathiazole. Sulfathiazole is an orally active, endocrine disruptor targeting the steroidogenic pathway, specifically enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and upregulating the mRN expression of CYP17, CYP19, and 3β-HSD. Sulfathiazole increases the production of 17-estradiol (E2) and has endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish[1][2][3][4].分子量：259.34Formula：C9H5D4N3O2S2CAS 号：1020719-89-4非标记 CAS：72-14-0性状：固体颜色：White to off-white中文名称：磺胺噻唑-d4；磺胺塞唑-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： 99.90%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-236. [Content Brief][2]. Ji K, Choi K, Lee S, Park S, Khim JS, Jo EH, Choi K, Zhang X, Giesy JP. Effects of sulfathiazole, oxytetracycline and chlortetracycline on steroidogenesis in the human adrenocarcinoma (H295R) cell line and freshwater fish Oryzias latipes. J Hazard Mater. 2010 Oct 15;182(1-3):494-502. [Content Brief][3]. Endicott, et al. Lesions in rats given sulfathiazole, sulfadiazine, sulfanilamide, sulfamerazine, sulfapyrazine, or acetylsulfadiazine in purified diets. Public Health Reports (1896-1970) (1944): 49-54.[4]. Zor, et al. Sulfathiazole as potential corrosion inhibitor for copper in 0.1 M NaCl. Protection of Metals and Physical Chemistry of Surfaces 50
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CAS:1128086-25-8|Donepezil-d5，多奈哌齐-d5; E2020-d5 free base
作者：德尔塔生物 日期：2025-07-08
生物活性：Donepezil-d5 is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Donepezil-d5 相关抗体:CHRNA9 AntibodyChAT Antibody分子量：384.52Formula：C24H24D5NO3CAS 号：1128086-25-8非标记 CAS：120014-06-4性状：固体颜色：White to off-white中文名称：多奈哌齐-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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CAS:1427049-21-5|Brexpiprazole-d8，OPC-34712-d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Brexpiprazole-d8 (OPC-34712-d8) is the deuterium labeled Brexpiprazole (HY-15780). Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM)[2][3].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Brexpiprazole-d8 相关抗体:ADRB2 AntibodyDRD2 AntibodyMTNR1A AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Salbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：441.62Formula：C25H19D8N3O2SCAS 号：1427049-21-5非标记 CAS：913611-97-9性状：固体颜色：White to off-white中文名称：依匹哌唑 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： ≥99.0%参考文献[1]. Ishima T, et al. Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: a role for serotonin 5-HT1A and 5-HT2A receptors. Eur Neuropsychopharmacol.
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CAS:2143107-55-3|Olaparib-d4-1，AZD2281-d4-1; KU0059436-d4-1
作者：德尔塔生物 日期：2025-07-08
生物活性：Olaparib-d4-1 (AZD2281-d4-1) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[1][2][3][4].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Olaparib-d4-1 相关抗体:PARP1 AntibodyPARP2 AntibodyCleaved PARP AntibodyCleaved-PARP1 AntibodyPARP1 Antibody (YA245)StAR AntibodySSB Antibody (YA668)GTF2H1 Antibody (YA1067)BRAT1 Antibody (YA2294)BRCC36 Antibody (YA2298)Killin Antibody (YA3144)分子量：438.49Formula：C24H19D4FN4O3CAS 号：2143107-55-3非标记 CAS：763113-22-0性状：固体颜色：White to off-white中文名称：奥拉帕尼 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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