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CAS:1028809-90-6|Glimepiride-d5，格列美脲 d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Glimepiride-d5 is the deuterium labeled Glimepiride. Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Glimepiride-d5 相关抗体:RAGE AntibodyPMP70 Antibody (YA1628)Amyloid Precursor Protein Antibody (YA1130)Serum Amyloid A Antibody (YA1168)DISC1 Antibody (YA2430)Phospho-Amyloid Precursor Protein (Thr743) Antibody (YA2568)APLP2 Antibody (YA2722)LRRC15 Antibody (YA3182)Mint3 Antibody (YA3242)分子量：495.65Formula：C24H29D5N4O5SCAS 号：1028809-90-6非标记 CAS：93479-97-1中文名称：格列美脲 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Geisen, K., Special pharmacology of the new sulfonylurea glimepiride. Arzneimittelforschung, 1988. 38(8): p. 1120-30. [Content Brief][3]. Liu, F., et al., Glimepiride attenuates Abeta production via suppressing BACE1 activit
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CAS:1189423-94-6|Propylthiouracil-d5，6-n-Propylthiouracil-d5; 6-Propyl-2-thiouracil-d5; PTU-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Propylthiouracil-d5 is the deuterium labeled Propylthiouracil. Propylthiouracil (6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：175.26Formula：C7H5D5N2OSCAS 号：1189423-94-6非标记 CAS：51-52-5中文名称：丙硫氧嘧啶 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Nakamura, H., et al., Comparison of methimazole and propylthiouracil in patients with hyperthyroidism caused by Graves' disease. J Clin Endocrinol Metab, 2007. 92(6): p. 2157-62. [Content Brief][3]. Taurog, A. and M.L. Dorris, A reexamination of the proposed inactivation of thyroid peroxidase in the rat thyroid by propylthiouracil. Endocrinology, 1989. 124(6): p. 3038-42. [Content Brief]
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CAS:1219806-45-7|Chlorpheniramine-d6 maleate
作者：德尔塔生物 日期：2025-07-08
生物活性：Chlorpheniramine-d6 (maleate) is the deuterium labeled Chlorpheniramine maleate[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：396.90Formula：C20H17D6ClN2O4CAS 号：1219806-45-7非标记 CAS：113-92-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (517 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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CAS:1185146-24-0|(Rac-Remelteon-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：(Rac)-Remelteon-d3 is the deuterium labeled (Rac)-Remelteon[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：262.36Formula：C16H18D3NO2CAS 号：1185146-24-0非标记 CAS：196597-17-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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CAS:1189947-02-1|Promethazine-d6 hydrochloride，(±-Promethazine-d6 (hydrochloride
作者：德尔塔生物 日期：2025-07-08
生物活性：Promethazine-d6 (hydrochloride) is the deuterium labeled Promethazine hydrochloride. Promethazine hydrochloride is an orally active histamine receptor antagonist[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Promethazine-d6 hydrochloride 相关抗体:ADGRE1 (F4/80) Antibody (YA002)ADGRE1 (F4/80) Antibody (YA920)分子量：326.92Formula：C17H15D6ClN2SCAS 号：1189947-02-1非标记 CAS：58-33-3性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Burt DR, et al. Antischizophrenic drugs: chronic treatment elevates dopamine receptor binding in brain. Science. 1977 Apr 15;196(4287):326-8. [Content Brief]
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CAS:1346603-27-7|Secnidazole-d6，RP-14539-d6; PM-185184-d6
作者：德尔塔生物 日期：2025-07-08
生物活性：Secnidazole-d6 is the deuterium labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research[1].IC50 & Target：Amebae体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：191.22Formula：C7H5D6N3O3CAS 号：1346603-27-7非标记 CAS：3366-95-8中文名称：塞克硝唑 d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (537 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Petrina MAB, et al. Susceptibility of bacterial vaginosis (BV)-associated bacteria to secnidazole compared to metronidazole, tinidazole and clindamycin. Anaerobe. 2017 Oct;47:115-119. [Content Brief]
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CAS:1287076-43-0|Albendazole-d7，SKF-62979-d7
作者：德尔塔生物 日期：2025-07-08
生物活性：Albendazole-d7 is the deuterium labeled Albendazole. Albendazole is a broad-spectrum parasiticide with high effectiveness and low host toxicity. Albendazole is used for the research gastrointestinal parasites in humans and animals[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：272.37Formula：C12H8D7N3O2SCAS 号：1287076-43-0非标记 CAS：54965-21-8中文名称：阿苯达唑 d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Li L, et al. Determination of albendazole and metabolites in silkworm Bombyx mori hemolymph by ultrafast liquid chromatography tandem triple quadrupole mass spectrometry. PLoS One. 2014;9(9):e105637. Published 2014 Sep 25. [Content Brief][3]. Mutavdžić Pavlović D, et al. Sorption of albendazole in sediments and soils: Isotherms and kinetics. Chemosphere. 2018;193:635-644. [Content Brief]
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CAS:1189938-30-4|Baclofen-d4，巴氯芬 d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Baclofen-d4 is the deuterium labeled Baclofen. Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Baclofen-d4 相关抗体:GABARAP AntibodyIP3 Receptor Antibody (YA1596)GABA B Receptor 2 Antibody (YA1733)GABA B Receptor 1 Antibody (YA2418)GAD65 Antibody (YA758)GABA A Receptor alpha 1 Antibody (YA1315)GABA A Receptor beta 2 Antibody (YA1758)GABA Transporter 1 Antibody (YA1795)GAD67 Antibody (YA1807)ABAT Antibody (YA1964)GABA A Receptor alpha 5 Antibody (YA2249)GABA A Receptor beta 1 Antibody (YA2261)BGAT Antibody (YA2741)GABARAPL2 Antibody (YA2882)分子量：217.69Formula：C10H8D4ClNO2CAS 号：1189938-30-4非标记 CAS：1134-47-0性状：固体颜色：White to off-white中文名称：巴氯芬 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:124020-27-5|Levosulpiride-d3，RV-12309-d3; S-(--Sulpiride-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：Levosulpiride-d3 is the deuterium labeled Levosulpiride. Levosulpiride (RV-12309) is the (S)-enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic agent of the benzamide class[1][2].IC50 & Target：D3 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Levosulpiride-d3 相关抗体:DRD2 AntibodyMTNR1A AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：344.44Formula：C15H20D3N3O4SCAS 号：124020-27-5非标记 CAS：23672-07-3性状：固体颜色：White to off-white中文名称：左舒必利 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1225580-94-8|Acamprosate-d3 calcium
作者：德尔塔生物 日期：2025-07-08
生物活性：Acamprosate-d3 (calcium) is the deuterium labeled Acamprosate calcium. Acamprosate calcium is a GABA receptor agonist and modulator of glutamatergic systems[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Acamprosate-d3 calcium 相关抗体:PSD95 AntibodyGABARAP AntibodyNMDAR1 AntibodyNMDAR2A AntibodyIonotropic Glutamate Receptor 2 Antibody (YA1143)GRM5 Antibody (YA1509)IP3 Receptor Antibody (YA1596)GABA B Receptor 2 Antibody (YA1733)Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845) Antibody (YA2081)GABA B Receptor 1 Antibody (YA2418)NR2E1 Antibody (YA2648)GAD65 Antibody (YA758)NR2F2 Antibody (YA1223)GABA A Receptor alpha 1 Antibody (YA1315)GABA A Receptor beta 2 Antibody (YA1758)GABA Transporter 1 Antibody (YA1795)GAD67 Antibody (YA1807)KA1 Antibody (YA1879)ABAT Antibody (YA1964)GABA A Receptor alpha 5 Antibody (YA2249)GABA A Receptor beta 1 Antibody (YA2261)GRIK2 Antibody (YA2705)BGAT Antibody (YA2741)GABARAPL2 Antibody (YA2882)PSD93 Antibody (YA3187)分子量：203.26Formula：C5H7D3CaNO4S+CAS 号：1225580-94-8非标记 CAS：77337-73-6性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -8
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CAS:2714316-71-7|Zuclomiphene-d4 citrate
作者：德尔塔生物 日期：2025-07-08
生物活性：Zuclomiphene-d4 (citrate) is a deuterium labeled Zuclomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent[1][2][3][4].分子量：602.11Formula：C32H32D4ClNO8CAS 号：2714316-71-7非标记 CAS：7619-53-6性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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CAS:2070009-63-9|Ivabradine-d6 hydrochloride，盐酸伊伐布雷定 D6
作者：德尔塔生物 日期：2025-07-08
生物活性：Ivabradine-d6 (hydrochloride) is the deuterium labeled Ivabradine hydrochloride. Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent.分子量：511.08Formula：C27H31D6ClN2O5CAS 号：2070009-63-9非标记 CAS：148849-67-6性状：固体颜色：White to off-white中文名称：盐酸伊伐布雷定 d6 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1185995-18-9|Pentoxifylline-d5，BL-191-d5; PTX-d5; Oxpentifylline-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Pentoxifylline-d5 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pentoxifylline-d5 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)PDE1B Antibody (YA1553)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)PDE4D Antibody (YA1714)Tat SF1 Antibody (YA2886)分子量：283.34Formula：C13H13D5N4O3CAS 号：1185995-18-9非标记 CAS：6493-05-6性状：固体颜色：White to off-white中文名称：己酮可可碱 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:557794-38-4|Dapsone-d8，4,4′-Diaminodiphenyl sulfone-d8; DDS-d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Dapsone-d8 is a deuterium labeled Dapsone. Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with antibacterial, antigenic and anti-inflammatory activities[1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone can be used as an anticonvulsant and also in the research of skin and glioblastoma diseases[2][3][4][5].体外研究(In Vitro)：氨苯砜 (0.06 mM; 30 min) 抑制 N-Formyl-Met-Leu-Phe.html" class="link-product" target="_blank">N-Formyl-Met-Leu-Phe (HY-P0224) (1 μM) 和生理激动剂 C5a (100 nM) 触发的细胞内外超氧化物 (O2-) 和胰蛋白酶 E 的释放，而不是对 Phorbol 12-myristate 13-acetate.html" class="link-product" target="_blank">Phorbol 12-myristate 13-acetate (HY-18739) (100 nM) 没有作用[5]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Dapsone-d8 相关抗体:Catalase Antibody (YA552)Catalase Antibody (YA811)MRP2 AntibodyC Reactive Protein Antibody (YA941)Elongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)PARK7/DJ1 Antibody (YA1799)Sulfadimidine Antibody (YA906)C Reactive Protein Antibody (YA939)C Reactive Protein Antibody (YA940)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)PON1 Antibody (YA1666)PON2 Antibody (YA1688)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Anti
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CAS:1189649-47-5|Oxprenolol-d7 hydrochloride，Ba 39089-d7
作者：德尔塔生物 日期：2025-07-08
生物活性：Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Oxprenolol-d7 hydrochloride 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：308.85Formula：C15H17D7ClNO3CAS 号：1189649-47-5非标记 CAS：6452-73-9性状：固体颜色：White to off-white中文名称：盐酸氧烯洛尔 d7 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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