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Cyanine3.5 carboxylic acid
作者：德尔塔 日期：2022-09-29
Non-reactive reference dye or controlCyanine3.5 carboxylic acid is an orange emitting dye used as a non-reactive reference dye or control. Cyanine3.5 is an analog of Cy3.5® fluorophore. Cyanine3.5 free unactivated monofunctional carboxylic acid.Cas No. SDF 化学名 3-(5-carboxypentyl)-1,1-dimethyl-2-((1E,3E)-3-(1,1,3-trimethyl-1H-benzo[e]indol-2(3H)-ylidene)prop-1-en-1-yl)-1H-benzo[e]indol-3-ium chloride Canonical SMILES CN1C2=CC=C3C=CC=CC3=C2C(C)(C)/C1=C\C=C\C4=[N+](CCCCCC(O)=O)C5=CC=C(C=CC=C6)C6=C5C4(C)C.[Cl-] 分子式 C38H41ClN2O2 分子量 593.2 溶解度 ≥ 59.3mg/mL in DMSO, ≥ 47.4 mg/mL in EtOH 储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cyanine3.5 azide
作者：德尔塔 日期：2022-09-29
别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C44H53ClN6O 分子量 717.38 溶解度 soluble in organic solvents (DMF, DMSO, dichloromethane), insoluble in water 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cyanine3.5 alkyne
作者：德尔塔 日期：2022-09-29
dye alkyne for click chemistryCyanine3.5 alkyne is a fluorophore that reacted with azides by copper-catalyzed click reaction. It is particularly suitable for the detection and labeling of azide-containing molecules/ biomolecules with fluorescence spectroscopy after azide-alkyne cycloaddition. This dye is not water-soluble, but it can be efficiently attached to water-soluble molecules (e.g protein or peptides) with organic co-solvent (DMSO or DMF). 化学名 1,1-dimethyl-3-(6-oxo-6-(prop-2-yn-1-ylamino)hexyl)-2-((1E,3E)-3-(1,1,3-trimethyl-1H-benzo[e]indol-2(3H)-ylidene)prop-1-en-1-yl)-1H-benzo[e]indol-3-ium chloride Canonical SMILES CC(C1=C(C=CC=C2)C2=CC=C1N/3C)(C)C3=C/C=C/C4=[N+](CCCCCC(NCC#C)=O)C(C=CC5=C6C=CC=C5)=C6C4(C)C.[Cl-] 分子式 C41H44ClN3O 分子量 630.26 溶解度 ≥ 63mg/mL in DMSO, ≥ 50.5 mg/mL in EtOH 储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cyanine3 tetrazine
作者：德尔塔 日期：2022-09-29
别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C40H46N7BF4O 分子量 727.64 溶解度 good in DCM, DMSO, DMF 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cyanine3 maleimide
作者：德尔塔 日期：2022-09-29
别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C36H43N4O3BF4 分子量 666.56 溶解度 well soluble in DMSO (0.50 M = 330 g/L), in DMF, dichloromethane, very poorly soluble in water (0.57 mM = 420 mg/L) 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cyanine3 hydrazide
作者：德尔塔 日期：2022-09-29
别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C30H40Cl2N4O 分子量 543.57 溶解度 moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols) 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cyanine3 DBCO
作者：德尔塔 日期：2022-09-29
别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C51H57N4O2PF6 分子量 902.99 溶解度 good in DMF, DMSO, DCM, alcohols, practically insoluble in water (< 1 uM, < 1 mg/L) 储存条件 Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cyanine3 carboxylic acid
作者：德尔塔 日期：2022-09-29
Cas No. 1361402-15-4 (inner salt), 1032678-01-5 (chloride), 1251915-29-3 (iodide) SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C30H37ClN2O2 分子量 493.08 溶解度 soluble in organic solvents (DMF, DMSO, dichloromethane), poorly soluble in water (1.8 g/L = 4.0 mM) 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cyanine3 azide
作者：德尔塔 日期：2022-09-29
Cas No. 1167421-28-4 (chloride) SDF 别名 N/A 化学名 N/A Canonical SMILES N/A 分子式 C33H43N6OCl 分子量 575.19 溶解度 soluble in organic solvents (DMF, DMSO, dichloromethane), practically insoluble in water (40 mg/L = 60 uM) 储存条件 Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cy5.5-SE
作者：德尔塔 日期：2022-09-27
Cy5.5-SE 是一种花青染料，可标记多肽、蛋白和寡核苷酸中的氨基。Cy5.5-SE is a cyanine dye, labeling amino-groups in peptides, proteins, and oligonucleotides.Cy5.5-SE is a cyanine dye, labeling amino-groups in peptides, proteins, and oligonucleotides.Cas No. 442912-55-2 SDF 别名 N/A 化学名 N/A Canonical SMILES O=S(C1=CC(S(=O)([O-])=O)=C2C(C3=C([N+](CC)=C(/C=C/C=C/C=C4N(CCCCCC(ON5C(CCC5=O)=O)=O)C6=C(C7=CC(S(=O)(O)=O)=CC(S(=O)(O)=O)=C7C=C6)C/4(C)C)C3(C)C)C=C2)=C1)(O)=O 分子式 C45H47N3O16S4 分子量 1014.13 溶解度 Soluble in DMSO 储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cy5.5 NHS ester (non-sulfonated)
作者：德尔塔 日期：2022-09-27
Cy5.5-NHS ester is a near-infrared amine reactive dye for labeling amino groups of peptides, proteins and oligonucleotides.Quality Control & SDS View current batch: 54321 Purity: >98.00% COA (Certificate Of Analysis) Datasheet Purity: >98.00% COA (Certificate Of Analysis) Datasheet Purity: >98.00% COA (Certificate Of Analysis) Datasheet Purity: >98.00% COA (Certificate Of Analysis) Datasheet Purity: >98.00% COA (Certificate Of Analysis) Datasheet jQuery(document).ready(function(){ jQuery('#selectqc').change(function(){ var val = jQuery(this).val(); show_or_hidden(val,5); }) }); Quality Control & SDS View current batch: 54321 Purity: >98.00% COA (Certificate Of Analysis) Datasheet Purity: >98.00% COA (Certificate Of Analysis) Datasheet Purity: >98.00% COA (Certificate Of Analysis) Datasheet Purity: >98.00% COA (Certificate Of Analysis) Datasheet Purity: >98.00% COA (Certificate Of Analysis) Datasheet jQuery(document).ready(function(){ jQuery('#selectqc').change(function(){ var val = jQuery(this).val(); show_or_hidden(val,5); }) });Cell experiment [1]:Cell lines U87MGPreparation Method U87MG cells (1 ×
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Cy5.5 hydrazide (non-sulfonated)
作者：德尔塔 日期：2022-09-27
carbonyl-reactive dyeCy5.5 hydrazide is a reactive dye for the labeling of biomolecules containing carbonyl groups, such as ketone and aldehydes. This dye pocesses a hydrazide group that can be used to label glycans at their reducing end or other reducing sugars, forming a hydrazone linkage. Hydrazide-containing Cyanine Dyes can react with glycoproteins and other glycoconjugates specifically via their carbohydrate groups without interfering binding site or active centers. Glycoproteins also can be labeled after periodate oxidation to form aldehyde groups. Therefore, this dye is especially applicable for the labeling of antibody. Moreover, Cy5.5 is a near infrared fluorophore with prominent ability of tissue penetration, so it is suitable for the applications which require low fluorescence background, and for the in vivo NIR imaging. For biomolecule labeling, the labeling regent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer.Cy5.5 hydrazide is a reactive dye for the labeling of biomolecules containing carbonyl groups, such as ketone and aldehydes. This dye pocesses a hydrazide group that can be used to label glycans at their reducing end or other reducing sugars, forming a hydrazone linkage. Hydrazide-containing Cyanine Dyes can react with glycoproteins and other glycoconjugates specifically via their carbohydrate groups without interfering binding site or active centers.
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Cy5.5 carboxylic acid (non-sulfonated)
作者：德尔塔 日期：2022-09-27
Non-reactive fluorophore, for control experiments, and for calibrationCy5.5 carboxylic acid is an un-activated labeling regent which has low aqueous solubility. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. Cyanine 5.5 carboxylic acid instead of the drug was injected into the tumors in order to visually observe the dye release by using the in vivo imaging system (IVIS). Research show that NIR irradiation could efficiently triggered drug release from the DEPt-PEG/α-CD hydrogel in vivo [1].Reference:[1] Wang, X. ; Wang, C.; Zhang, Q.; Cheng, Y. Near Infrared Light-responsive and Injectable Supramolecular Hydrogels for On-demand Drug Delivery. Chemical Communications, 2016, 52, 978–981.Cy5.5 carboxylic acid is an un-activated labeling regent which has low aqueous solubility. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. Cyanine 5.5 carboxylic acid instead of the drug was injected into the tumors in order to visually observe the dye release by using the in vivo imaging system (IVIS). Research show that NIR irradiation could efficiently triggered drug release from the DEPt-PEG/α
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Cy5.5 azide (non-sulfonated)
作者：德尔塔 日期：2022-09-27
used for Click chemistry to label alkyne-modified oligonucleotidesThis Cy5.5 is a labeling reagent that ready for the use in Click Chemistry reaction which available as 10 mM solution in DMSO. As Cy5.5 azide is a far-red emitting dye, it can replace Alexa Fluor 680, and DyLight 680. Most derivatives of non-sulfonated cyanines have low aqueous solubility except for hydrochlorides of hydrazides and amines. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. In human glioblastoma U87MG cells, to assess the capability of the Cu(I)/M-dots for cell labeling Cy5.5-azide was in combination with Cu(I)/M-dots for imaging of the integrin αⅤβ3 receptor [1].Reference:[1] Sun, Y. ; Hong, S.; Ma, X.; Cheng, K.; Wang, J.; Zhang, Z.; Yang, M.; Jiang, Y.; Hong, X.; Cheng, Z. Recyclable Cu(I)/Melanin Dots for Cycloadditions, Bioconjugation and Cell Labeling. Chemical Science.This Cy5.5 is a labeling reagent that ready for the use in Click Chemistry reaction which available as 10 mM solution in DMSO. As Cy5.5 azide is a far-red emitting dye, it can replace Alexa Fluor 680, and DyLight 680. Most derivatives of non-sulfonated cyanines have low aqueous solubility except for hydrochlorides of hydrazides and amines. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is nec
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Cy5.5 alkyne (non-sulfonated)
作者：德尔塔 日期：2022-09-27
远红外/近红外染料，用于点击化学标记Cy5.5 alkyne (non-sulfonated)是一种远红外/近红外染料炔，含有乙炔基，用于点击化学标记。Cyanine5.5是Cy5.5®的类似物，Cy5.5®是一种常见的荧光团，被广泛用于各种应用，包括完整的生物体成像。Cy5.5 alkyne (non-sulfonated)在温和铜催化的点击化学条件下可以与叠氮基团结合。Cy5.5 alkyne (non-sulfonated)可溶于有机溶剂，但水与小百分比的DMSO混合物可用于有效的缀合反应。Cy5.5 alkyne (non-sulfonated)也可用于标记小分子。Cy5.5 alkyne (non-sulfonated)是一种远红外/近红外染料炔，含有乙炔基，用于点击化学标记。Cyanine5.5是Cy5.5®的类似物，Cy5.5®是一种常见的荧光团，被广泛用于各种应用，包括完整的生物体成像。Cy5.5 alkyne (non-sulfonated)在温和铜催化的点击化学条件下可以与叠氮基团结合。Cy5.5 alkyne (non-sulfonated)可溶于有机溶剂，但水与小百分比的DMSO混合物可用于有效的缀合反应。Cy5.5 alkyne (non-sulfonated)也可用于标记小分子。Cas No. N/A SDF 别名 N/A 化学名 N/A Canonical SMILES CN1C2=CC=C3C=CC=CC3=C2C(C)(C)/C1=C\C=C\C=C\C4=[N+](CCCCCC(NCC#C)=O)C5=CC=C(C=CC=C6)C6=C5C4(C)C.[Cl-] 分子式 C43H46ClN3O 分子量 656.3 溶解度 >65.6 mg/mL in DMSO; insoluble in H2O; >13 mg/mL in EtOH 储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while
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