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CAS:73962-07-9|Urethane-d5，Ethyl carbamate-d5; Carbamic acid ethyl ester-d5; Ethylurethane-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Urethane-d5 is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Urethane-d5 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：94.12Formula：C3H2D5NO2CAS 号：73962-07-9非标记 CAS：51-79-6性状：固体颜色：White to off-white中文名称：氨基甲酸乙酯 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:344298-99-3|Propranolol-d7 (ring-d7，盐酸普萘洛尔 d7
作者：德尔塔生物 日期：2025-07-08
生物活性：Propranolol-d7 (ring-d7) is the deuterium labeled Propranolol hydrochloride. Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM[2]. Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Propranolol-d7 (ring-d7) 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：266.39Formula：C16H14D7NO2CAS 号：344298-99-3非标记 CAS：318-98-9性状：固体颜色：Off-white to light yellow中文名称：盐酸普萘洛尔 d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:98897-23-5|Propranolol-d7，普萘洛尔 d7
作者：德尔塔生物 日期：2025-07-08
生物活性：Propranolol-d7 is the deuterium labeled Propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1]. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM[2]. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Propranolol-d7 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：266.39Formula：C16H14D7NO2CAS 号：98897-23-5非标记 CAS：525-66-6性状：固体颜色：White to off-white中文名称：普萘洛尔 d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1219795-30-8|Felodipine-d3，非洛地平 d3
作者：德尔塔生物 日期：2025-07-08
生物活性：Felodipine-d3 is the deuterium labeled Felodipine. Felodipine, a dihydropyridine, is a potent, vasoselective calcium channel antagonist. Felodipine lowers blood pressure (BP) by selective action on vascular smooth muscle, especially in the resistance vessels. Felodipine, an anti-hypertensive agent, induces autophagy. Felodipine can cross the blood-brain barrier[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Felodipine-d3 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCardiac Troponin I/TNNC1 AntibodySCGN Antibody (YA1167)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)CRCP Antibody (YA3350)Annexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)CAB39 Antibody (YA2761)CUG BP1 Antibody (YA2806)C10orf63 Antibody (YA2894)ITPK1 Antibody (YA3125)ORAI3 Antibody (YA3128)ORAI1 Antibody (YA3157)CREB Regulated Transcription Coactivator
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CAS:1188266-14-9|Nifedipine-d6，硝苯地平 D6; BAY-a-1040-d6
作者：德尔塔生物 日期：2025-07-08
生物活性：Nifedipine-d6 is deuterium labeled nifedipine, and nifedipine is a potent calcium channel blocker.分子量：352.37Formula：C17H12D6N2O6CAS 号：1188266-14-9非标记 CAS：21829-25-4性状：固体颜色：Light yellow to yellow中文名称：硝苯地平 d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1189426-07-0|Glipizide-d11，格列吡嗪 d11
作者：德尔塔生物 日期：2025-07-08
生物活性：Glipizide-d11 is the deuterium labeled Glipizide. Glipizide (CP 2872; K 4024) a potent, orally active and sulfonylurea class anti-diabetic agent and can be used for type 2 diabetes mellitus research but not type 1. Glipizide acts by partially blocking ATP-sensitive potassium (KATP) channels among β cells of pancreatic islets of Langerhans[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Glipizide-d11 相关抗体:ATP1A1 AntibodyLGI1 Antibody (YA2885)Cardiac Troponin C Antibody (YA2125)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)Kir2.1 Antibody (YA2871)分子量：456.60Formula：C21H16D11N5O4SCAS 号：1189426-07-0非标记 CAS：29094-61-9性状：固体颜色：White to light brown中文名称：格列吡嗪 d11运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： 96.36%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. B J Zünkler, et al. Concentration-dependent effects of tolbutamide, meglitinide, glipizide, glibenclamide and diazoxide on ATP-regulated K+ currents in pancreatic B-cel
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CAS:1189650-58-5|Candesartan-d5，坎地沙坦 d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Candesartan-d5 is the deuterium labeled Candesartan. Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Candesartan-d5 相关抗体:Natriuretic Peptides A Antibody (YA1381)Angiotensinogen Antibody (YA2097)Natriuretic Peptides B Antibody (YA999)Natriuretic Peptides B Antibody (YA1000)Natriuretic Peptides B Antibody (YA1001)AGTR2 Antibody (YA3090)Angiotensin II Type 1 Receptor Antibody (YA3358)分子量：445.48Formula：C24H15D5N6O3CAS 号：1189650-58-5非标记 CAS：139481-59-7性状：固体颜色：Off-white to light brown中文名称：坎地沙坦 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1219170-21-4|Ofloxacin-d8，氧氟沙星 d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Ofloxacin-d8 (Hoe-280-d8) is the deuterium labeled Ofloxacin. Ofloxacin (Hoe-280) is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ofloxacin-d8 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：369.42Formula：C18H12D8FN3O4CAS 号：1219170-21-4非标记 CAS：82419-36-1性状：固体颜色：White to light yellow中文名称：氧氟沙星 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1398065-75-2|Ketoconazole-d4，Ketoconazol-d4; R 41400-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Ketoconazole-d4 is the deuterium labeled Ketoconazole. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ketoconazole-d4 相关抗体:Cytochrome C AntibodyRab5 AntibodyRAB8A AntibodyEpac1 AntibodyGRB2 AntibodyRAB7 AntibodyRas AntibodyRASA1 AntibodyRhoA Antibody (YA093)SDHA AntibodyCytochrome P450 17A1 AntibodyAromatase AntibodyRhoA AntibodyRhoA/B/C AntibodyCYP11A1 AntibodyRab10 Antibody (YA1789)Rab7B Antibody (YA1798)Rab9 Antibody (YA1800)GTPase NRAS Antibody (YA1830)GTPase HRAS Antibody (YA1833)Cytochrome P450 1B1 Antibody (YA1836)Adrenodoxin Antibody (YA2005)Cytochrome P450 27A1 Antibody (YA2163)Cytochrome P450 2C9 Antibody (YA2166)Rab4 Antibody (YA2272)Cytochrome P450 2E1 Antibody (YA2302)IQGAP1 Antibody (YA2388)G3BP Antibody (YA2432)Cytochrome P450 Reductase Antibody (YA2619)Thromboxane A Synthase Antibody (YA2670)分子量：535.46Formula：C26H24D4Cl2N4O4CAS 号：1398065-75-2非标记 CAS：65277-42-1性状：固体颜色：White to light yellow中文名称：酮康唑 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1228765-67-0|Edaravone-d5，MCI-186-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Edaravone-d5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator[1][2][3][4].分子量：179.23Formula：C10H5D5N2OCAS 号：1228765-67-0非标记 CAS：89-25-8性状：固体颜色：Off-white to light yellow中文名称：依达拉奉 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： 99.52%参考文献[1]. Yoshida, H., et al. Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury. CNS Drug Rev, 2006. 12(1): p. 9-20. [Content Brief][2]. Okamura, K., et al. Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia. Neurol Res, 2013. [Content Brief][3]. Garcia CA, et al. Edaravone reduces astrogliosis and apoptosis in young rats with kaolin-induced hydrocephalus. Childs Nerv Syst. 2016 Dec 17. [Epub ahead of print] [Content Brief][4]. Bai X, et al. Protective Effect of Edaravone on Glutamate-Induced Neurotoxicity in Spiral Ganglion Neurons. Neural Plast. 2016;2016:4034218. Epub 2016 Nov 10. [Content Brief]
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CAS:1346602-15-0|Orotic acid-13C,15N2 monohydrate，乳清酸-13C,15N2; 6-Carboxyuracil-13C,15N2 monohydrate; Vitamin B13-13C,15N2 monohydrate
作者：德尔塔生物 日期：2025-07-08
生物活性：Orotic acid-13C,15N2 (monohydrate) is the 13C and 15N labeled Orotic acid[1]. Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats[2][3][4].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Orotic acid-13C,15N2 monohydrate 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：177.09Formula：C413CH615
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CAS:72963-19-0|trans-Zeatin-d5，反-玉米素-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：trans-Zeatin-d5 is deuterium labeled trans-Zeatin. trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.trans-Zeatin-d5 相关抗体:BNSP AntibodyFACL4 AntibodyMEK1/2 AntibodyBrdU Antibody (YA578)ERK1/2 AntibodyPhospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) AntibodyPhospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Antibody (YA455)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyERK2 AntibodyPhospho-MEK1 (Ser298) AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)ERK5 AntibodyLamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyMEK1 AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)ERK1 AntibodyLaminin beta 1 AntibodyHeme Oxygenase 1 Antibody分子量：224.27Formula：C10H8D5N5OCAS 号：72963-19-0非标记 CAS：1637-39-4性状：固体颜色：White to off-white中文名称：反-玉米素-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1133712-26-1|Posaconazole-d4，泊沙康唑-d4; SCH 56592-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Posaconazole-d4 is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity[1].分子量：704.80Formula：C37H38D4F2N8O4CAS 号：1133712-26-1非标记 CAS：171228-49-2性状：固体颜色：White to off-white中文名称：泊沙康唑-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1794941-44-8|Chlorthalidone-d4，氯噻酮 d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Chlorthalidone-d4 is the deuterium labeled Chlorthalidone. Chlorthalidone is a thiazide-like diuretic used to treat hypertension.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：342.79Formula：C14H7D4ClN2O4SCAS 号：1794941-44-8非标记 CAS：77-36-1性状：固体颜色：White to off-white中文名称：氯噻酮 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:2749293-95-4|Empagliflozin-d4，恩格列净-d4; BI 10773-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Empagliflozin-d4 is deuterium labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：454.93Formula：C23H23D4ClO7CAS 号：2749293-95-4非标记 CAS：864070-44-0性状：固体颜色：White to off-white中文名称：恩格列净-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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