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CAS:1377838-49-7|Pomalidomide-d5,泊马度胺-d5; CC-4047-d5

CAS:1377838-49-7|Pomalidomide-d5,泊马度胺-d5; CC-4047-d5

作者:德尔塔生物 日期:2025-07-08

生物活性:Pomalidomide-d5 is deuterium labeled Pomalidomide. Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors.IC50 & Target:Cereblon体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pomalidomide-d5 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量:278.27Formula:C13H6D5N3O4CAS 号:1377838-49-7非标记 CAS:19171-19-8中文名称:泊马度胺-d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Dat

CAS:1279026-26-4|Benazepril-d5 hydrochloride,盐酸贝那普利-d5; CGS14824A-d5 hydrochloride

CAS:1279026-26-4|Benazepril-d5 hydrochloride,盐酸贝那普利-d5; CGS14824A-d5 hydrochloride

作者:德尔塔生物 日期:2025-07-08

生物活性:Benazepril-d5 hydrochloride is deuterium labeled Benazepril hydrochloride. Benazepril hydrochloride is an orally active angiotensin-converting enzyme (ACE) inhibitor to reduce angiotensin-II production. Benazepril hydrochloride inhibits oxidative stress and inhibits apoptosis by the PI3K/Akt signaling pathway. In addition, Benazepril hydrochloride improves diabetic nephropathy and decreases proteinuria. Benazepril hydrochloride can be used in the study of hypertension, heart failure and diabetic nephropathy[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Benazepril-d5 hydrochloride 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)Phospho-AKT1 (Ser473) AntibodyAKT1/2/3 Antibody (YA633)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyPhospho-AKT (Thr308) AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyPhospho-AKT1(Ser473) Antibodyc-Myc AntibodyCyclin E1 AntibodyACE2 AntibodyAIF Antibody (YA636)AKT1 Antibody (YA834)AKT1 Antibody (YA634)ALIX AntibodyCatalase Antibody (YA552)Catalase Antibody (YA811)CNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cy

CAS:2714486-61-8|Tilmicosin-d3,LY-177370-d3; EL-870-d3

CAS:2714486-61-8|Tilmicosin-d3,LY-177370-d3; EL-870-d3

作者:德尔塔生物 日期:2025-07-08

生物活性:Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Tilmicosin-d3 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)iNOS AntibodyDYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase Antibody分子量:872.15Formula:C46H77D3N2O13CAS 号:2714486-61-8非标记 CAS:108050-54-0性状:固体颜色:

CAS:1188263-49-1|Leriglitazone-d4,MIN-102-d4;  Hydroxypioglitazone-d4

CAS:1188263-49-1|Leriglitazone-d4,MIN-102-d4; Hydroxypioglitazone-d4

作者:德尔塔生物 日期:2025-07-08

生物活性:Leriglitazone-d4 (MIN-102-d4; Hydroxypioglitazone-d4) is deuterium labeled Leriglitazone. Leriglitazone is an orally active and a BBB-penatrable PPARγ agonist with an EC50 of 9 μM. Leriglitazone, as a regulator of mitochondrial function, has neuroprotective, anti-inflammatory and antioxidant effects. Leriglitazone can be used in the study of neuroinflammatory and neurodegenerative diseases[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Leriglitazone-d4 相关抗体:PPAR alpha AntibodyPPAR gamma AntibodyPPAR gamma Antibody (YA122)PGC1 beta Antibody (YA1411)分子量:376.46Formula:C19H16D4N2O4SCAS 号:1188263-49-1非标记 CAS:146062-44-4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Mosure SA,et al. Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPARγ Drug Pioglitazone. J Med Chem. 2019 Feb 28;62(4):200

CAS:1217818-36-4|Zilpaterol-d7,齐帕特罗-d7

CAS:1217818-36-4|Zilpaterol-d7,齐帕特罗-d7

作者:德尔塔生物 日期:2025-07-08

生物活性:Zilpaterol-d7 is a deuterium Zilpaterol. Zilpaterol is a β-adrenergic agonist that have been widely used to feed cattle[1].IC50 & Target:β adrenergic receptor体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Zilpaterol-d7 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量:268.36Formula:C14H12D7N3O2CAS 号:1217818-36-4非标记 CAS:119520-05-7中文名称:齐帕特罗-d7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (540 KB)产品使用指南 (1538 KB)参考文献[1]. Piña-Olmos S, et al. Extracellular and intracellular zilpaterol and clenbuterol quantification in Hep G2 liver cells by UPLC-PDA and UPLC-MS/MS. J Pharm Biomed Anal. 2021 Feb 20;195:113817. [Content Brief][2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

CAS:1219805-81-8|Benzyl 4-hydroxybenzoate-d4,Benzylp-Hydrocybenzoate-d4

CAS:1219805-81-8|Benzyl 4-hydroxybenzoate-d4,Benzylp-Hydrocybenzoate-d4

作者:德尔塔生物 日期:2025-07-08

生物活性:Benzyl 4-hydroxybenzoate-d4 is the deuterium labeled Benzyl 4-hydroxybenzoate[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:232.27Formula:C14H8D4O3CAS 号:1219805-81-8中文名称:对羟基苯甲酸苯甲酯-d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (518 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

CAS:35692-88-7|Formamide-d1,甲酰胺-d1

CAS:35692-88-7|Formamide-d1,甲酰胺-d1

作者:德尔塔生物 日期:2025-07-08

生物活性:Formamide-d1 is the deuterium labeled Formamide[1]. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Formamide-d1 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:46.05Formula:CH2DNOCAS 号:35692-88-7中文名称:甲酰胺-d1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of

CAS:362049-51-2|Methyl paraben-d4,Methyl 4-hydroxybenzoate-d4

CAS:362049-51-2|Methyl paraben-d4,Methyl 4-hydroxybenzoate-d4

作者:德尔塔生物 日期:2025-07-08

生物活性:Methyl paraben-d4 is the deuterium labeled Methyl Paraben[1]. Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Methyl paraben-d4 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:156.17Formula:C8H4D4O3CAS 号:362049-51-2非标记 CAS:99-76-3性状:固体颜色:White

CAS:1356841-18-3|Perindoprilat-d4

CAS:1356841-18-3|Perindoprilat-d4

作者:德尔塔生物 日期:2025-07-08

生物活性:Perindoprilat-d4 is the deuterium labeled Perindoprilat[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Perindoprilat-d4 相关抗体:ACE2 AntibodyACE AntibodyACE Antibody (YA2094)分子量:344.44Formula:C17H24D4N2O5CAS 号:1356841-18-3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

CAS:911392-40-0|Nivalenol-13C15,雪腐镰刀菌烯醇-13C15

CAS:911392-40-0|Nivalenol-13C15,雪腐镰刀菌烯醇-13C15

作者:德尔塔生物 日期:2025-07-08

生物活性:Nivalenol-13C15 is the 13C labeled Nivalenol (HY-N6801)[1]. Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product[2]. Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect[3].IC50 & Target:caspase[2]体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:327.20Formula:13C15H20O7CAS 号:911392-40-0非标记 CAS:23282-20-4中文名称:雪腐镰刀菌烯醇-13C15运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (546 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. [Content Brief][2]. Bryła M, et al. Natural Occurrence of Nivalenol, Deoxynivalenol, and Deoxynivalenol-3-Glucoside in Polish Winter Wheat. Toxins (Basel). 2018 Feb 13;10(2). [Content Brief][3]. Aupanun S, et al. Individual and combined mycotoxins deoxynivalenol, nivalenol, and fusarenon-X induced apoptosis in lymphoid tissues of mice after oral exposure. Toxicon.

CAS:1353867-99-8|Patulin-13C7,棒曲霉素-13C7; Terinin-13C7

CAS:1353867-99-8|Patulin-13C7,棒曲霉素-13C7; Terinin-13C7

作者:德尔塔生物 日期:2025-07-08

生物活性:Patulin-13C7 (Terinin-13C7) is the 13C labeled Patulin (HY-N6779)[1]. Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, is suspected to be clastogenic, mutagenic, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage[2][3][4][5].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:161.07Formula:13C7H6O4CAS 号:1353867-99-8非标记 CAS:149-29-1中文名称:展青霉素-13C7;棒曲霉素-13C7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (532 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. [Content Brief]

CAS:2819816-90-3|Fumonisin B3-13C34,伏马菌素-13C34

CAS:2819816-90-3|Fumonisin B3-13C34,伏马菌素-13C34

作者:德尔塔生物 日期:2025-07-08

生物活性:Fumonisin B3-13C34 is the 13C labeled Fumonisin B3 (HY-N6726)[1]. Fumonisin B3 is a mycotoxin derived from fusarium fungi, a member of fumonisins[2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:739.58Formula:13C34H59NO14CAS 号:2819816-90-3非标记 CAS:1422359-85-0中文名称:伏马菌素B2-13C34运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. [Content Brief][2]. Gelderblom WC, et al. Fumonisins: isolation, chemical characterization and biological effects. Mycopathologia. 1992 Feb;117(1-2):11-6. [Content Brief]

CAS:1217481-36-1|Fumonisin B2-13C34,伏马菌素B2-13C34

CAS:1217481-36-1|Fumonisin B2-13C34,伏马菌素B2-13C34

作者:德尔塔生物 日期:2025-07-08

生物活性:Fumonisin B2-13C34 is the 13C labeled Fumonisin B2 (HY-N6723)[1]. Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis[2][3].IC50 & Target:Sphingosine N-acyltransferase[2]体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:739.58Formula:13C34H59NO14CAS 号:1217481-36-1非标记 CAS:116355-84-1中文名称:伏马菌素B2-13C34运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (534 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. [Content Brief][2]. Henry MH, et al. The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. Poult Sci. 2001 Apr;80(4):401-7. [Content Brief][3]. Wei T, et al. Natural occurrence of fumonisins B1 and B2 in corn in four provinces of China. Food Addit Contam Part B Surveill. 2013;6(4):270-4. [Content Brief]

CAS:1217458-62-2|Fumonisin B1-13C34,伏马菌素B1-13C34

CAS:1217458-62-2|Fumonisin B1-13C34,伏马菌素B1-13C34

作者:德尔塔生物 日期:2025-07-08

生物活性:Fumonisin B1-13C34 is the 13C labeled Fumonisin B1 (HY-N6719)[1]. Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin[2][3].IC50 & Target:Sphingosine N-acyltransferase[2]体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。Fumonisin B1 改变猴肾细胞基因表达和信号转导通路[2]。Fumonisin B1 增加鞘脂代谢的初始破坏和鞘氨醇在 LLC-PK1 肾细胞中的积累,导致大鼠星形胶质细胞凋亡型 DNA 损伤[2]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:755.58Formula:13C34H59NO15CAS 号:1217458-62-2非标记 CAS:116355-83-0中文名称:伏马菌素B1-13C34运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (536 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. [Content Brief][2]. Henry MH, et al. The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. Poult Sci. 2001 Apr;80(4):401-7. [Content Brief][3]. Wang SK, et al. Effect of fumonisin B₁ on the cell cycle of normal human liver cells. Mol Med Rep. 2013 Jun;7(6):1970-6. [

CAS:911392-39-7|15-Acetyl-deoxynivalenol-13C17

CAS:911392-39-7|15-Acetyl-deoxynivalenol-13C17

作者:德尔塔生物 日期:2025-07-08

生物活性:15-Acetyl-deoxynivalenol-13C17 is the 13C labeled 15-Acetyl-deoxynivalenol (HY-N6683)[1]. 15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals, and a metabolite of deoxynivalenol, exhibits toxicity to HepG2 cells[2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:355.23Formula:13C17H22O7CAS 号:911392-39-7非标记 CAS:88337-96-6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (538 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. [Content Brief][2]. Juan-García A, et al. Binary and tertiary combination of alternariol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol on HepG2 cells: Toxic effects and evaluation of degradation products. Toxicol In Vitro. 2016 Aug;34:264-273. [Content Brief]