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「同位素标记抑制剂」CAS:1129408-57-6|Pemetrexed-d5
作者：德尔塔生物 日期：2025-10-20
生物活性：Pemetrexed-d5 is the deuterium labeled Pemetrexed[1]. Pemetrexed (LY231514) is an antifolate, the Ki values of the pentaglutamate of Pemetrexed (LY231514) are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：432.44Formula：C20H16D5N5O6CAS 号：1129408-57-6非标记 CAS：137281-23-3中文名称：培美曲塞二钠盐-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Shih C, et al. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes. Cancer Res. 1997 Mar 15;57(6):1116-23. [Content Brief][3]. Anraku M, et al. Synergistic antitumor effects of regulatory T cell blockade combined with pemetrexed in murine malignantmesothelioma. J Immunol. 2010 Jul 15;185(2):956-
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「同位素标记抑制剂」CAS:1219274-96-0|Clopidogrel-d4 sulfate
作者：德尔塔生物 日期：2025-10-20
生物活性：Clopidogrel-d4 (sulfate) is the deuterium labeled Clopidogrel sulfate[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：423.92Formula：C16H14D4ClNO6S2CAS 号：1219274-96-0非标记 CAS：135046-48-9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」CAS:61219-76-9|DL-Mevalonolactone-d3
作者：德尔塔生物 日期：2025-10-20
生物活性：DL-Mevalonolactone-d3 is the deuterium labeled DL-Mevalonolactone[1]. DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential ( Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling[2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.DL-Mevalonolactone-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：133.16Formula：C6H7D3O3CAS 号：61219-76-9非标记 CAS：674-26-0运输条件：Room temperature in continental US; may
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「同位素标记抑制剂」CAS:2714473-25-1|Delapril-d3 hydrochloride
作者：德尔塔生物 日期：2025-10-20
生物活性：Delapril-d3 (hydrochloride) is the deuterium labeled Delapril hydrochloride. Delapril hydrochloride is an angiotensin-converting enzyme (ACE) inhibitor for the treatment of cardiovascular diseases[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Delapril-d3 hydrochloride 相关抗体:ACE2 AntibodyACE AntibodyACE Antibody (YA2094)分子量：492.02Formula：C26H30D3ClN2O5CAS 号：2714473-25-1非标记 CAS：83435-67-0中文名称：地拉普利盐酸盐 d3 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Razzetti R, et al. Pharmacokinetic and pharmacologic properties of delapril, a lipophilic nonsulfhydryl angiotensin-converting enzyme inhibitor. Am J Cardiol. 1995 Jun 16;75(18):7F-12F. [Content Brief]
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「同位素标记抑制剂」CAS:345909-03-7|Valproic acid-d4-1
作者：德尔塔生物 日期：2025-10-20
生物活性：Valproic acid-d4-1 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Valproic acid-d4-1 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyHDAC1 AntibodyHDAC6 AntibodyMETTL3 AntibodyHDAC4 Antibody (YA741)TSG101 AntibodySATB2 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)CD4 AntibodyHDAC10 AntibodyHDAC2 AntibodyHDAC3 AntibodyHDAC4 AntibodyJagged1 AntibodyLamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)NUMB AntibodyOPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)分子量：148.24Formula：C8H12D4O2CAS 号：345909-03-7非标记 CAS：99-66-1中文名称：丙戊酸-d4-1运输条件：Room temperature in cont
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「同位素标记抑制剂」CAS:2747917-55-9|Flurbiprofen-13C,d3
作者：德尔塔生物 日期：2025-10-20
生物活性：Flurbiprofen-13C,d3 is the 13C- and deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[64].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Flurbiprofen-13C,d3 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量：248.27Formula：C1413CH10D3FO2CAS 号：2747917-55-9非标记 CAS：5104-4
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「同位素标记抑制剂」CAS:1051418-95-1|Nevirapine-d4
作者：德尔塔生物 日期：2025-10-20
生物活性：Nevirapine-d4 is deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM[1].IC50 & Target：HIV-1分子量：270.32Formula：C15H10D4N4OCAS 号：1051418-95-1非标记 CAS：129618-40-2性状：固体颜色：White to off-white中文名称：奈韦拉平 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1216908-63-2|AR-A014418-d3
作者：德尔塔生物 日期：2025-10-20
生物活性：AR-A014418-d3 is the deuterium labeled AR-A014418. AR-A014418 is a potent, selective, and ATP-competitive GSK3β inhibitor (IC50=104 nM; Ki=38 nM)[1].分子量：311.33Formula：C12H9D3N4O4SCAS 号：1216908-63-2非标记 CAS：487021-52-3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Bhat R, Xue Y, Berg S, Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J Biol Chem. 2003 Nov 14;278(46):45937-45. [Content Brief]
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「同位素标记抑制剂」CAS:142741-60-4|Tenidap-d3
作者：德尔塔生物 日期：2025-10-20
生物活性：Tenidap-d3 is the deuterium labeled Tenidap. Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC50 values of 0.03 μM and 1.2 μM for COX-1 and COX-2, respectively. Tenidap has anti-inflammatory and antirheumatic properties[1][2]. Tenidap is also a specific SLC26A3 inhibitor[3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Tenidap-d3 相关抗体:COX2 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCOX IV Antibody (YA867)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)分子量：323.77Formula：C14H6D3ClN2O3SCAS 号：142741-60-4非标记 CAS：120210-48-2运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (533 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Kirchner T, et al. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation. J Pharmacol Exp Ther. 1997 Aug;282(2):1094-10
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「同位素标记抑制剂」CAS:2712343-38-7|Raltegravir-d4
作者：德尔塔生物 日期：2025-10-20
生物活性：Raltegravir-d4 is deuterium labeled Raltegravir. Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Raltegravir-d4 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)Tat SF1 Antibody (YA2886)分子量：448.44Formula：C20H17D4FN6O5CAS 号：2712343-38-7非标记 CAS：518048-05-0中文名称：雷特格韦-d4；拉替拉韦-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Hare, S., et al., Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance. Proc Natl Acad Sci U S A, 2010. 107(46): p. 20057-62. [Content Brief][3]. Xu P, et al. Combined Medication of Antiretroviral Drugs Tenofovir Disoproxil Fumarate, Emtricitabine, and Raltegravir Reduces Neural Progenitor Cell Proliferation In Vivo and In Vitro. J
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25-羟基维生素D2-D3|25-Hydroxyvitamin D2-d3
作者：德尔塔生物 日期：2025-10-17
产品货号：DT20251458产品品牌：德尔塔生物中文名称：25-羟基维生素D2-D3CAS：1217467-39-4英文名称：25-Hydroxyvitamin D2-d3化学纯度：大于99%丰度：5％～99％物理性质：无色液体包装：0.5g~1000g螺口玻璃瓶包装，塑料内塞或铝箔封口，外套热缩膜德尔塔生物具有稳定性同位素分离、同位素标记化合物合成、同位素检测技术研究实力，具有13C、15N、18O、22Ne等稳定同位素分离技术。本公司成功开发了化学交换法、水精馏法、热扩散法、低温精馏法等分离稳定性同位素的方法，并实现了工业化生产。目前具有年产40公斤15N、100 公斤18O、批量化22Ne、20Ne同位素生产的能力，以及1029余种同位素标记化合物开发能力。欢迎来电咨询。德尔塔生物具备年产100公斤18O、40公斤15N、批量化22Ne、20Ne同位素及13C同位素生产和供货能力；具备合成氘、碳-13、氮-15、氧-18标记的农用示踪剂、氘代试剂、标记氨基酸（可带保护基团）、标记多肽、标记诊断试剂、标记有机试剂、标记标准样品等1000多种同位素标记产品的能力。
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25-羟基维生素D3-D6|25-Hydroxyvitamin D3-d6
作者：德尔塔生物 日期：2025-10-17
产品货号：DT20251457产品品牌：德尔塔生物中文名称：25-羟基维生素D3-D6CAS：78782-98-6英文名称：25-Hydroxyvitamin D3-d6化学纯度：大于99%丰度：5％～99％物理性质：无色液体包装：0.5g~1000g螺口玻璃瓶包装，塑料内塞或铝箔封口，外套热缩膜德尔塔生物具有稳定性同位素分离、同位素标记化合物合成、同位素检测技术研究实力，具有13C、15N、18O、22Ne等稳定同位素分离技术。本公司成功开发了化学交换法、水精馏法、热扩散法、低温精馏法等分离稳定性同位素的方法，并实现了工业化生产。目前具有年产40公斤15N、100 公斤18O、批量化22Ne、20Ne同位素生产的能力，以及1029余种同位素标记化合物开发能力。欢迎来电咨询。德尔塔生物具备年产100公斤18O、40公斤15N、批量化22Ne、20Ne同位素及13C同位素生产和供货能力；具备合成氘、碳-13、氮-15、氧-18标记的农用示踪剂、氘代试剂、标记氨基酸（可带保护基团）、标记多肽、标记诊断试剂、标记有机试剂、标记标准样品等1000多种同位素标记产品的能力。
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25-羟基维生素D2-D6|25-Hydroxyvitamin D2-d6
作者：德尔塔生物 日期：2025-10-17
产品货号：DT20251456产品品牌：德尔塔生物中文名称：25-羟基维生素D2-D6CAS：1262843-46-8英文名称：25-Hydroxyvitamin D2-d6化学纯度：大于99%丰度：5％～99％物理性质：无色液体包装：0.5g~1000g螺口玻璃瓶包装，塑料内塞或铝箔封口，外套热缩膜德尔塔生物具有稳定性同位素分离、同位素标记化合物合成、同位素检测技术研究实力，具有13C、15N、18O、22Ne等稳定同位素分离技术。本公司成功开发了化学交换法、水精馏法、热扩散法、低温精馏法等分离稳定性同位素的方法，并实现了工业化生产。目前具有年产40公斤15N、100 公斤18O、批量化22Ne、20Ne同位素生产的能力，以及1029余种同位素标记化合物开发能力。欢迎来电咨询。德尔塔生物具备年产100公斤18O、40公斤15N、批量化22Ne、20Ne同位素及13C同位素生产和供货能力；具备合成氘、碳-13、氮-15、氧-18标记的农用示踪剂、氘代试剂、标记氨基酸（可带保护基团）、标记多肽、标记诊断试剂、标记有机试剂、标记标准样品等1000多种同位素标记产品的能力。
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茚并(1.2.3-C.D)芘-D12|Indeno[1,2,3-cd]pyrene-d12
作者：德尔塔生物 日期：2025-10-17
产品货号：DT20251455产品品牌：德尔塔生物中文名称：茚并(1.2.3-C.D)芘-D12CAS：203578-33-0英文名称：Indeno[1,2,3-cd]pyrene-d12化学纯度：大于99%丰度：5％～99％物理性质：无色液体包装：0.5g~1000g螺口玻璃瓶包装，塑料内塞或铝箔封口，外套热缩膜德尔塔生物具有稳定性同位素分离、同位素标记化合物合成、同位素检测技术研究实力，具有13C、15N、18O、22Ne等稳定同位素分离技术。本公司成功开发了化学交换法、水精馏法、热扩散法、低温精馏法等分离稳定性同位素的方法，并实现了工业化生产。目前具有年产40公斤15N、100 公斤18O、批量化22Ne、20Ne同位素生产的能力，以及1029余种同位素标记化合物开发能力。欢迎来电咨询。德尔塔生物具备年产100公斤18O、40公斤15N、批量化22Ne、20Ne同位素及13C同位素生产和供货能力；具备合成氘、碳-13、氮-15、氧-18标记的农用示踪剂、氘代试剂、标记氨基酸（可带保护基团）、标记多肽、标记诊断试剂、标记有机试剂、标记标准样品等1000多种同位素标记产品的能力。
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二苯并[A,H]蒽-D14|Dibenz[a,h]anthracene-d14
作者：德尔塔生物 日期：2025-10-17
产品货号：DT20251454产品品牌：德尔塔生物中文名称：二苯并[A,H]蒽-D14CAS：13250-98-1英文名称：Dibenz[a,h]anthracene-d14化学纯度：大于99%丰度：5％～99％物理性质：无色液体包装：0.5g~1000g螺口玻璃瓶包装，塑料内塞或铝箔封口，外套热缩膜德尔塔生物具有稳定性同位素分离、同位素标记化合物合成、同位素检测技术研究实力，具有13C、15N、18O、22Ne等稳定同位素分离技术。本公司成功开发了化学交换法、水精馏法、热扩散法、低温精馏法等分离稳定性同位素的方法，并实现了工业化生产。目前具有年产40公斤15N、100 公斤18O、批量化22Ne、20Ne同位素生产的能力，以及1029余种同位素标记化合物开发能力。欢迎来电咨询。德尔塔生物具备年产100公斤18O、40公斤15N、批量化22Ne、20Ne同位素及13C同位素生产和供货能力；具备合成氘、碳-13、氮-15、氧-18标记的农用示踪剂、氘代试剂、标记氨基酸（可带保护基团）、标记多肽、标记诊断试剂、标记有机试剂、标记标准样品等1000多种同位素标记产品的能力。
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