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「同位素标记抑制剂」Genistein-d4
作者：德尔塔生物 日期：2025-09-18
生物活性：Genistein-d4 is the deuterium labeled Genistein. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Genistein-d4 相关抗体:BNSP AntibodyFACL4 Antibodyc-Fos AntibodyBrdU Antibody (YA578)ERK1/2 AntibodyCaveolin-1 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyMETTL3 Antibodyc-Myc AntibodyCyclin E1 AntibodyPhospho-EGFR (Tyr1068) AntibodyPhospho-EGFR (Tyr1173) AntibodyTSG101 AntibodyAIF Antibody (YA636)ALIX AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)c-Fos Antibody (YA506)分子量：274.26Formula：C15H6D4O5CAS 号：187960-08-3非标记 CAS：446-72-0性状：固体颜色：White to off-white中文名称：染料木素 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3
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「同位素标记抑制剂」Linezolid-d3
作者：德尔塔生物 日期：2025-09-18
生物活性：Linezolid-d3 is a deuterium labeled Linezolid (PNU-100766). Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis[1].分子量：340.36Formula：C16H17D3FN3O4CAS 号：1127120-38-0非标记 CAS：165800-03-3性状：固体颜色：White to off-white中文名称：利奈唑胺 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Voriconazole-d3
作者：德尔塔生物 日期：2025-09-18
生物活性：Voriconazole-d3 is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Voriconazole-d3 相关抗体:SDHA Antibody分子量：352.33Formula：C16H11D3F3N5OCAS 号：1217661-14-7非标记 CAS：137234-62-9性状：固体颜色：White to off-white中文名称：伏立康唑 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Palbociclib-d8
作者：德尔塔生物 日期：2025-09-18
生物活性：Palbociclib-d8 is a deuterium labeled Palbociclib. Palbociclib is a selective and orally active CDK4 and CDK6 inhibitor with IC50s of 11 and 16 nM, respectively. Palbociclib has the potential for ER-positive and HER2-negative breast cancer research[1].IC50 & Target[1]：Cdk4/cyclin D39 nM (IC50)Cdk4/cyclin D111 nM (IC50)Cdk6/cyclin D216 nM (IC50)DYRK1A2000 nM (IC50)MAPK8000 nM (IC50)体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Palbociclib-d8 相关抗体:Cyclin E1 Antibody (YA483)CD133 AntibodyCdk2 AntibodyCdk4 AntibodyCdk5 AntibodyCdk6 AntibodyCyclin D3 AntibodyCdk7 AntibodyCDK16 AntibodyCDK5 Antibody (YA796)CDK9 AntibodyCDKN2A/p16INK4a Antibody (YA508)Phospho-CDK1 (Tyr15) AntibodyPhospho-CDK1/2/3 (Thr14) AntibodyPhospho-CDK2 (Tyr15) AntibodyPhospho-Cyclin B1 (Ser126) AntibodyCDKN2A/p16INK4a AntibodyCDKN2C AntibodyPhospho-CDC6 (Ser54) Antibody (YA1017)Cyclin E2 Antibody (YA2594)CDC25C Antibody (YA2624)CDC6 Antibody (YA2626)CDC40 Antibody (YA3168)Cyclin A1/A2 Antibody (YA3336)CRK Antibody (YA790)Cyclin H Antibody (YA788)Cyclin H AntibodyPhospho-CDC6 (Ser106) Antibody (YA1016)CDC7 Antibody (YA1152)Cyclin D3/CCND3 Antibody (YA1201)分子量：455.58Formula：C24H21D8N7O2CAS 号：1628752-83-9非标记 CAS：571190-30-2性状：固体颜色：Light yellow to yellow中文名称：帕布昔利布 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C
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「同位素标记抑制剂」Abemaciclib-d8
作者：德尔塔生物 日期：2025-09-18
生物活性：Abemaciclib-d8 is the deuterium labeled Abemaciclib. Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Abemaciclib-d8 相关抗体:Cyclin E1 Antibody (YA483)CD133 AntibodyCdk2 AntibodyCdk4 AntibodyCdk5 AntibodyCdk6 AntibodyCyclin D3 AntibodyCdk7 AntibodyCDK16 AntibodyCDK5 Antibody (YA796)CDK9 AntibodyCDKN2A/p16INK4a Antibody (YA508)Phospho-CDK1 (Tyr15) AntibodyPhospho-CDK1/2/3 (Thr14) AntibodyPhospho-CDK2 (Tyr15) AntibodyPhospho-Cyclin B1 (Ser126) AntibodyCDKN2A/p16INK4a AntibodyCDKN2C AntibodyPhospho-CDC6 (Ser54) Antibody (YA1017)Cyclin E2 Antibody (YA2594)CDC25C Antibody (YA2624)CDC6 Antibody (YA2626)CDC40 Antibody (YA3168)Cyclin A1/A2 Antibody (YA3336)CRK Antibody (YA790)Cyclin H Antibody (YA788)Cyclin H AntibodyPhospho-CDC6 (Ser106) Antibody (YA1016)CDC7 Antibody (YA1152)Cyclin D3/CCND3 Antibody (YA1201)分子量：514.64Formula：C27H24D8F2N8CAS 号：2088650-53-5非标记 CAS：1231929-97-7性状：固体颜色：White to yellow运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」L-Tyrosine-d4
作者：德尔塔生物 日期：2025-09-18
生物活性：L-Tyrosine-d4 is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[1].体外研究(In Vitro)：L-Tyrosine inhibits citrate synthase activity in the posterior cortex (2.0 and 4.0 mM), malate dehydrogenase is not altered by L-Tyrosine and succinate dehydrogenase is increased in the posterior cortex (0.1-4.0 mM), hippocampus (1.0-4.0 mM), striatum (4.0 mM) and liver (0.1-4.0 mM)[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.L-Tyrosine-d4 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：185.21Formula：C9H7D4NO3CAS 号：62595-14-6非标记 CAS：60-18-4性状：固体颜色：White to off-white中文名称：L-酪氨酸-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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「同位素标记抑制剂」Aspirin-d3
作者：德尔塔生物 日期：2025-09-18
生物活性：Aspirin-d3 is the deuterium labeled Aspirin. Aspirin is a non-selective and irreversible inhibitor of COX-1 and COX-2 with IC50s of 5 and 210 μg/mL.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Aspirin-d3 相关抗体:S100A10 Antibody (YA675)COX2 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCOX IV Antibody (YA867)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)分子量：183.18Formula：C9H5D3O4CAS 号：921943-73-9非标记 CAS：50-78-2性状：固体颜色：White to off-white中文名称：阿司匹林 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」BMS-986202
作者：德尔塔生物 日期：2025-09-18
生物活性：BMS-986202 is a potent, selective and orally active Tyk2 inhibitor that binds to Tyk2 JH2 with an IC50 value of 0.19 nM and a Ki of 0.02 nM. BMS-986202 is remarkably selective over other kinases including Jak family members. BMS-986202 is also a weak inhibitor of CYP2C19 with an IC50 value of 14 μM. BMS-986202 can be used for IL-23-driven acanthosis, anti-CD40-induced colitis, and spontaneous lupus research. BMS-986202 is a de novo deuterium[1].IC50 & Target[1]：Tyk2 JH20.19 nM (IC50)Tyk2 JH20.02 nM (Ki)CYP2C1914 μM (IC50)体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。氘代化合物的潜在优势： (1) 延长半衰期体内。氘代化合物可能能够延长化合物的药代动力学特征，即延长体内半衰期。这可以提高化合物的安全性、功效和耐受性，并增加给药的便利性。 (2) 提高口服生物利用度。氘化化合物可以降低肠壁和肝脏中不需要的代谢 (首过代谢) 的程度，使更大比例的未代谢药物到达其作用靶点。高生物利用度决定了它在低剂量下的活性和更好的耐受性。(3) 改善代谢特性。氘代化合物可以减少有毒或反应性代谢物的形成并改善药物代谢。 (四) 提高用药安全性。氘代化合物可以减少或消除药物化合物的不良副作用并且是安全的。(5) 保持疗效。在先前的研究中，预计氘代化合物将保留与氢类似物相似的生化效力和选择性。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.BMS-986202 相关抗体:Phospho-JAK2 (Tyr1007/1008) AntibodyCytochrome C AntibodyJAK1 Antibody (YA722)JAK1 AntibodyJAK2 Antibody (YA721)Cytochrome P450 17A1 AntibodyPhospho-JAK2 (Tyr1007+Tyr1008) AntibodyAromatase A
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「同位素标记抑制剂」Ammonium chloride-15N
作者：德尔塔生物 日期：2025-09-18
生物活性：Ammonium chloride-15N is the 15N labeled Ammonium chloride (HY-Y1269). Ammonium chloride, as a heteropolar compound with pH value regulation, can cause intracellular alkalization and metabolic acidosis thus effecting enzymatic activity and influencing the process of biological system. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor[1][2][3].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：54.48Formula：ClH415NCAS 号：39466-62-1性状：固体颜色：White to off-white中文名称：氯化铵-15N运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Meropenem-d6
作者：德尔塔生物 日期：2025-09-18
生物活性：Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Meropenem-d6 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：389.50Formula：C17H19D6N3O5SCAS 号：1217976-95-8非标记 CAS：96036-03-2性状：固体颜色：Off-white to light yellow中文名称：美罗培南-d6；美洛培南-d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Folinic acid-d4 calcium hydrate，亚叶酸-d4; Leucovorin-d4 calcium hydrate「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-18
生物活性：Folinic acid-d4-1 (Leucovorin-d4-1) calcium hydrate is deuterated labeled Folinic acid (HY-17556). Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate.html" class="link-product" target="_blank">Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Folinic acid-d4 calcium hydrate 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)Formula：C20H17D4CaN7O7.xH2O非标记 CAS：58-05-9性状：固体颜色：White to off-white中文名称：亚叶酸-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, stored under nitrogen, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
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Xylitol-5-13C，Xylite-5-13C「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-18
生物活性：Xylitol-5-13C is the 13C labeled Xylit[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Xylitol-5-13C 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：153.14Formula：C413CH12O5非标记 CAS：87-99-0性状：固体颜色：White to off-white中文名称：木糖醇 5-13C运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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UDP-α-D-Galactose-13C disodium「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-18
生物活性：UDP-α-D-Galactose-13C (disodium) is the 13C labeled UDP-α-D-Galactose disodium salt[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：611.26Formula：C1413CH22N2Na2O17P2非标记 CAS：137868-52-1性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Asoxime-d4 dichloride，HI-6-d4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-18
生物活性：Asoxime-d4 (dichloride) is the deuterium labeled Asoxime dichloride. Asoxime dichloride (HI-6) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride involves in modulating immunity response. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Asoxime-d4 dichloride 相关抗体:J-chain Antibody (YA1290)PSCA Antibody (YA1479)Butyrylcholinesterase Antibody (YA2460)Nicotinic Acetylcholine Receptor alpha 4 Antibody (YA2616)Nicotinic Acetylcholine Receptor alpha 5 Antibody (YA2659)分子量：363.23Formula：C14H12D4Cl2N4O3非标记 CAS：34433-31-3性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度： ≥96.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Pohanka M, et al. HI-6 modulates immunization efficacy in a BALB/c mouse model.Envi
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Elexacaftor-d3，VX-445-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-18
生物活性：Elexacaftor-d3 (VX-445-d3) is the deuterium labeled Elexacaftor (HY-111772)[1].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。Elexacaftor (VX-445) 是一种下一代囊性纤维化跨膜电导调节 (CFTR) 校正剂，旨在恢复 Phe508del CFTR 蛋白的功能。Elexacaftor 有处理囊性纤维化的潜力。VX-445-Tezacaftor-VX-770 在双重组合时，显著改善了 Phe508del CFTR 蛋白加工、转运和氯化物转运[2]。Elexacaftor (VX-445) 是一种新一代囊性纤维化跨膜传导调节剂 (CFTR) 校正剂，旨在恢复 Phe508del CFTR蛋白功能。Elexacaftor (VX-445) 具有处理囊性纤维化的潜力。VX-445-Tezacaftor-VX-770 在双联用时显著改善了 Phe508del CFTR 蛋白的加工、运输和氯离子转运，其改善程度大于联合使用中两种化合物的任何一种[3]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：600.67Formula：C26H31D3F3N7O4S非标记 CAS：2216712-66-0性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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