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「同位素标记抑制剂」Tianeptine-d12
作者：德尔塔生物 日期：2025-06-13
生物活性：Tianeptine-d12 is a deuterated analog of Tianeptine. Tianeptine is an antidepressant with oral activity and neurochemical properties. Tianeptine has neuroprotective effects against hypoxia in tissue culture and against the deleterious effects of cytokines in the cortex and white matter, but not against NMDA receptor-mediated excitotoxicity[1][2][3][4].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：449.03Formula：C21H13D12ClN2O4SCAS 号：1189870-26-5非标记 CAS：72797-41-2中文名称：噻奈普汀 d12运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Wagstaff A J, et al. Tianeptine: a review of its use in depressive disorders[J]. CNS drugs, 2001, 15: 231-259.[3]. Plaisant F, et al. Neuroprotective properties of tianeptine: interactions with cytokines[J]. Neuropharmacology, 2003, 44(6): 801-809. [Content Brief][4]. Sharma A K, et al. Effects of calcium channel blocker,
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「同位素标记抑制剂」Palonosetron-d3 hydrochloride
作者：德尔塔生物 日期：2025-06-13
生物活性：Palonosetron-d3 (hydrochloride) is the deuterium labeled Palonosetron hydrochloride. Palonosetron hydrochloride is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV)[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Palonosetron-d3 hydrochloride 相关抗体:MTNR1A Antibody分子量：335.89Formula：C19H22D3ClN2OCAS 号：1246816-81-8非标记 CAS：135729-62-3中文名称：盐酸帕洛诺司琼 d3 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (559 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Vishnu Murthy M, Srinivas K, Kumar R, Mukkanti K.Development and validation of a stability-indicating LC method for determining palonosetron hydrochloride, its related compounds and degradation products using naphthalethyl stationary phase.J Pharm Biomed Anal. 2011 Sep 10;56(2):429-35. [Content Brief][3]. Ajioka H, Morita F, Akizawa Y, Yoshida K, Kitamura R, Takimoto H.Pharmacolog
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「同位素标记抑制剂」Perindopril-d4 erbumine
作者：德尔塔生物 日期：2025-06-13
生物活性：Perindopril-d4 t-butylamine salt is the deuterium labeled Perindopril t-butylamine salt. Perindopril t-butylamine salt is a long-acting ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Perindopril-d4 erbumine 相关抗体:ACE2 AntibodyACE AntibodyACE Antibody (YA2094)分子量：445.63Formula：C23H39D4N3O5CAS 号：1356929-59-3非标记 CAS：107133-36-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Vaclavik J, Perindopril in the treatment of hypertension and cardiovascular diseases: evolution continues with the orodispersible dosage form. Vnitr Lek. 2013 Apr;59(4):290-4. [Content Brief][3]. Napalkov DA. Therapy with perindopril: organoprotection, not just the antihypertensive effect. Kardiologiia. 2012;52(12):80-3. [Content Brief]
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「同位素标记抑制剂」rac cis-Moxifloxacin-d4 hydrochloride
作者：德尔塔生物 日期：2025-06-13
生物活性：rac cis-Moxifloxacin-d4 (hydrochloride) is the deuterium labeled Moxifloxacin hydrochloride. Moxifloxacin Hydrochloride (BAY 12-8039) is an oral 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia[1][2].IC50 & Target：Quinolone体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.rac cis-Moxifloxacin-d4 hydrochloride 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：441.92Formula：C21H21D4ClFN3O4CAS 号：1217802-65-7非标记 CAS：186826-86-8性状：固体颜色：White to light yellow中文名称：盐酸莫西沙星 d4 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Store at room temperature, keep dry and coolIn solvent：-80°C：2 years-2
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「同位素标记抑制剂」Vedaprofen-d3
作者：德尔塔生物 日期：2025-06-13
生物活性：Vedaprofen-d3 is the deuterium labeled Vedaprofen. Vedaprofen (Quadrisol) is a COX-1 selective nonsteroidal anti-inflammatory agent (NSAID) for serum TxB2 and exudate PGE2 inhibition [1]. Vedaprofen is a Escherichia coli (E. coli) sliding clamp (SC) inhibitor with the IC50 of 222 μM[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Vedaprofen-d3 相关抗体:COX2 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCOX IV Antibody (YA867)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)分子量：285.40Formula：C19H19D3O2CAS 号：1185054-34-5非标记 CAS：71109-09-6中文名称：维达洛芬-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. P Lees, et al. PK-PD integration and PK-PD modelling of nonsteroidal anti-inflammatory drugs: principles and applications in veterinary pharmacology. J Vet Pharmacol Ther. 2004 Dec;27(6):491-502. [Content Brief][3]. Zhou Yin
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「同位素标记抑制剂」Ethacrynic acid-13C2,d5
作者：德尔塔生物 日期：2025-06-12
生物活性：Ethacrynic acid-13C2,d5 is the deuterium and 13C labeled Ethacrynic acid[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ethacrynic acid-13C2,d5 相关抗体:Annexin VI AntibodyNF-KB p65 AntibodyPhospho-NF-KB p65 (Ser536) AntibodyPhospho-NF-κB p65 (Ser529) AntibodyNF-KB p65 Antibody (YA267)Calbindin AntibodyCalreticulin AntibodyNF-KB p105/p50 AntibodyRelB AntibodyRet AntibodyRetinoic Acid Receptor alpha AntibodySOD2 Antibody (YA071)SOX1 AntibodyTRAF2 AntibodyAnnexin A1 Antibody (YA832)DDX3 Antibody (YA784)NF-KB p100 AntibodyNF-KB p105 Antibody (YA700)Nrf1 AntibodyPhospho-NF-KB p65 (Thr254) AntibodySOD2 Antibody (YA670)TRAF6 AntibodyPhospho-NFKB1(Ser337) Antibody Nrf2 Antibody(YA895)Cardiac Troponin I/TNNC1 AntibodyDDIT3 AntibodyPhospho-NF-κB p65 (Ser536) AntibodyGST3 Antibody (YA975)SCGN Antibody (YA1167)RAMP1 Antibody (YA1818)分子量：310.15Formula：C1113C2H7D5Cl2O4非标记 CAS：58-54-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (516 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmac
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「同位素标记抑制剂」Ritonavir-13C,d3
作者：德尔塔生物 日期：2025-06-12
生物活性：Ritonavir-13C,d3 is the 13C- and deuterium labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ritonavir-13C,d3 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCD4 AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase Antibody分子量：724.96Formula：C3613CH45D3N6O5S2非标记 CAS：155213-67-5中文名称：利托那韦 13C,d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, e
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「同位素标记抑制剂」Zafirlukast-13C,d6
作者：德尔塔生物 日期：2025-06-12
生物活性：Zafirlukast-13C,d6 is the 13C- and deuterium labeled Zafirlukast. Zafirlukast (ICI 204219) is a potent orally active leukotriene D4 (LTD4) receptor antagonist. Zafirlukast shows anti-asthmatic, anti-inflammatory and anti-bacterial effects.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[45].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Zafirlukast-13C,d6 相关抗体:Leukotriene A4 Hydrolase Antibody (YA2400)分子量：582.70Formula：C3013CH27D6N3O6S非标记 CAS：107753-78-6中文名称：扎鲁司特-13C,d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief][2]. Finnerty JP, et al. Role of leukotrienes in exercise-induced asthma. Inhibitory effect of ICI 204219, a potent leukotriene D4 receptor antagonist. Am Rev Respir Dis. 1992 Apr;145(4 Pt 1):746-9. [Content Brief][3]. Gunning WT, et al. Chemoprevention by lipoxygenase and leukotriene pathway inhibitors of vinyl carbamate-induced lung tumors in mice. Cancer Res. 2002 Aug 1;62(15):4199-
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「同位素标记抑制剂」Sofosbuvir-13C,d3
作者：德尔塔生物 日期：2025-06-12
生物活性：Sofosbuvir-13C,d3 is the deuterium labeled Sofosbuvir. Sofosbuvir (PSI-7977) is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.分子量：533.46Formula：C2113CH26D3FN3O9P非标记 CAS：1190307-88-0性状：固体颜色：White to off-white中文名称：索非布韦 13C，d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料Data Sheet (502 KB)产品使用指南 (1538 KB)
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「同位素标记抑制剂」Almorexant-13C,d3
作者：德尔塔生物 日期：2025-06-12
生物活性：Almorexant-13C,d3 is the 13C- and deuterium labeled Almorexant. Almorexant (ACT 078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM, respectively.IC50 & Target：OX2 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Almorexant-13C,d3 相关抗体:OX40L Antibody (YA1475)OX40 Antibody (YA1504)分子量：516.57Formula：C2813CH28D3F3N2O3非标记 CAS：871224-64-5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (533 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Cruz HG, et al. Assessment of the abuse liability of a dual orexin receptor antagonist: a crossover study of almorexant and zolpidem in recreational drug users. CNS Drugs. 2014 Apr;28(4):361-72. [Content Brief][3]. Malherbe P, et al. Biochemical and electrophysiological characterization of almorexant, a dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist: comparison with sel
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「同位素标记抑制剂」Simeprevir-13C,d3
作者：德尔塔生物 日期：2025-06-12
生物活性：Simeprevir-13C,d3 is the 13C- and deuterium labeled Simeprevir. Simeprevir is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a Ki of 0.36 nM. Simeprevir inhibits HCV replication with an EC50 of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (Mpro) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses[1][2][5].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：753.95Formula：C3713CH44D3N5O7S2非标记 CAS：923604-59-5中文名称：西咪匹韦 13C，d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (539 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Raboisson P, et al. Structure-activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC4
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「同位素标记抑制剂」Treprostinil-13C2,d
作者：德尔塔生物 日期：2025-06-12
生物活性：Treprostinil-13C2,d is the 13C- and deuterium labeled Treprostinil. Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.IC50 & Target：EPDP体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[51].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Treprostinil-13C2,d 相关抗体:Prostaglandin D Synthase Antibody (YA1739)DP1 Antibody (YA2766)分子量：393.50Formula：C2113C2H33DO5非标记 CAS：81846-19-7中文名称：曲前列环素-13C2,d1；曲前列尼尔-13C2,d1运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief][2]. Whittle BJ, et al. Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: treprostinil is a potent DP1 and EP2 agonist. Biochem Pharmacol. 2012 Jul 1;84(1):68-75. [Content Brief][3]. Ferrantino M, et al. Inhaled treprostinil sodium for the treatment of pulmonary arterial hypertension. Expert Opin Pharmacother. 2011
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「同位素标记抑制剂」Kukoamine B-d5 dihydrochloride
作者：德尔塔生物 日期：2025-06-12
生物活性：Kukoamine B, a spermine alkaloid, is a potent dual LPS and CpG DNA inhibitor with Kd values of 1.23 µM and 0.66 µM, respectively. Kukoamine B exerts anti-inflammatory, anti-diabetic, anti-oxidant, anti-osteoporotic and neuroprotective effects. Kukoamine B has the potential for the study of sepsis. [1][2][3][4].分子量：608.61Formula：C28H39D5Cl2N4O6非标记 CAS：164991-67-7中文名称：地骨皮乙素二盐酸盐-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Li YY, et al. A Metabolomics Approach to Investigate Kukoamine B-A Potent Natural Product With Anti-diabetic Properties. Front Pharmacol. 2019 Jan 22;9:1575. [Content Brief][2]. Hu XL, et al. Neuroprotective effects of Kukoamine B against hydrogen peroxide-induced apoptosis and potential mechanisms in SH-SY5Y cells. Environ Toxicol Pharmacol. 2015 Jul;40(1):230-40. [Content Brief][3]. Park E, et al. Anti-Osteoporotic Effects of Kukoamine B Isolated from Lycii Radicis Cortex Extract on Osteoblast and Osteoclast Cells and Ovariectomized Osteoporosis Model Mice. Int J Mol Sci. 2019 Jun 6;20(11):2784. [Content Brief][4]. Liu X, et al. Kukoamine B, a novel dual inhibitor of LPS and CpG DNA, is a potential candidate for sepsis treatment. Br J Pharmacol. 2011 Mar;162(6):1274-90. [Content Brief]
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「同位素标记抑制剂」Thymidine-13C-2
作者：德尔塔生物 日期：2025-06-12
生物活性：Thymidine-13C-2 is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Thymidine-13C-2 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCtip2 AntibodyMETTL3 AntibodyRb AntibodyPhospho-Rb (Ser807) AntibodyTSG101 AntibodyRPA32 Antibody (YA679)Alkaline Phosphatase AntibodyCalnexin Antibody (YA573)CDT1 AntibodyDNA-PKcs/PRKDC AntibodyHes1 AntibodyJunB AntibodyLamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyLIN28A AntibodyLin28B AntibodyMCM2 AntibodyNanog AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)Nucleolin AntibodyOPA1 Antibody分子量：243.22Formula：C913CH14N2O5非标记 CAS：50-89-5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmac
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「同位素标记抑制剂」(R)-Verapamil-d7 hydrochloride
作者：德尔塔生物 日期：2025-06-12
生物活性：(R)-Verapamil-d7 (hydrochloride) is a deuterium labeled (R)-Verapamil hydrochloride. (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents[1][2].分子量：498.11Formula：C27H32D7ClN2O4非标记 CAS：38176-02-2中文名称：盐酸维拉帕米杂质22-d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Plumb JA, et al. The activity of verapamil as a resistance modifier in vitro in drug resistant human tumour cell lines is not stereospecific. Biochem Pharmacol. 1990 Feb 15;39(4):787-92. [Content Brief][2]. Perrotton T, et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007 Oct 26;282(43):31542-8. Epub 2007 Jul 22. [Content Brief]
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