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「同位素标记抑制剂」CAS:158776-07-9|Dibenzo(a,i)pyrene-d14
作者：德尔塔生物 日期：2025-06-11
生物活性：Dibenzo(a,i)pyrene-d14 is the deuterium labeled Dibenzo(a,i)pyrene[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：316.45Formula：C24D14CAS 号：158776-07-9非标记 CAS：189-55-9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」CAS:2470226-50-5|Trifloxystrobin-d6
作者：德尔塔生物 日期：2025-06-11
生物活性：Trifloxystrobin-d6 is the deuterium labeled Trifloxystrobin. Trifloxystrobin (CGA 279202) is a fungicide, with EC50s of 23.0 μg/L and 1.7 μg/L for Daphnia magna neonate and embryos, respectively, after treatment for 48 h[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Trifloxystrobin-d6 相关抗体:SDHA Antibody分子量：414.41Formula：C20H13D6F3N2O4CAS 号：2470226-50-5非标记 CAS：141517-21-7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Cui F, et al. Toxicity of three strobilurins (kresoxim-methyl, pyraclostrobin, and trifloxystrobin) on Daphnia magna. Environ Toxicol Chem. 2017 Jan;36(1):182-189. [Content Brief]
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「同位素标记抑制剂」CAS:2468638-25-5|Mefruside-d3
作者：德尔塔生物 日期：2025-06-11
生物活性：Mefruside-d3 is the deuterium labeled Mefruside[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：385.90Formula：C13H16D3ClN2O5S2CAS 号：2468638-25-5非标记 CAS：7195-27-9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」CAS:2260669-12-1|Dihydrolanosterol-d7
作者：德尔塔生物 日期：2025-06-11
生物活性：Dihydrolanosterol-d7 is deuterium labeled Dihydrolanosterol. Dihydrolanosterol is a subtrate of CYP51 and a cholesterol biosynthesis inhibitor[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Dihydrolanosterol-d7 相关抗体:Cytochrome C AntibodyCytochrome P450 17A1 AntibodyAromatase AntibodyCYP11A1 AntibodyCytochrome P450 1B1 Antibody (YA1836)Adrenodoxin Antibody (YA2005)Cytochrome P450 27A1 Antibody (YA2163)Cytochrome P450 2C9 Antibody (YA2166)Cytochrome P450 2E1 Antibody (YA2302)Cytochrome P450 Reductase Antibody (YA2619)Thromboxane A Synthase Antibody (YA2670)Cytochrome P450 3A4 Antibody (YA3365)HSD11B1 Antibody (YA3376)Cytochrome P450 17A1 Antibody (YA786)CYP2E1 AntibodyCYP1A2 AntibodyPLSCR3 Antibody (YA1672)PROX1 Antibody (YA1754)Cytochrome P450 4A Antibody (YA2087)Cytochrome P450 24A1 Antibody (YA2121)Cytochrome P450 26A1 Antibody (YA2259)COX5B Antibody (YA2550)Steroidogenic Factor 1 Antibody (YA3166)Dynein Light Chain Tctex Type 1 Antibody (YA3263)Cytochrome P450 2D6 Antibody (YA3384)分子量：435.78Formula：C30H45D7OCAS 号：2260669-12-1非标记 CAS：79-62-9性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn sol
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「同位素标记抑制剂」CAS:1246815-96-2|Aliskiren-d6 hydrochloride
作者：德尔塔生物 日期：2025-06-11
生物活性：Aliskiren-d6 (hydrochloride) is is deuterium labeled Aliskiren, which is a direct renin inhibitor.分子量：594.26Formula：C30H48D6ClN3O6CAS 号：1246815-96-2非标记 CAS：173399-03-6中文名称：阿利吉仑 d6 盐酸盐运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (492 KB)产品使用指南 (1538 KB)
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「同位素标记抑制剂」CAS:1246819-94-2|Citalopram-d6 oxalate
作者：德尔塔生物 日期：2025-06-11
生物活性：Citalopram-d6 oxalate is the deuterium labeled Citalopram oxalate[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：420.46Formula：C22H17D6FN2O5CAS 号：1246819-94-2非标记 CAS：59729-33-8中文名称：西酞普兰-d6草酸盐运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」CAS:1219803-58-3|Citalopram-d4 hydrobromide
作者：德尔塔生物 日期：2025-06-11
生物活性：Citalopram-d4 (hydrobromide) is the deuterium labeled Citalopram hydrobromide. Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI)[1].分子量：409.33Formula：C20H18D4BrFN2OCAS 号：1219803-58-3非标记 CAS：59729-32-7性状：固体颜色：White to off-white中文名称：西酞普兰-d4 (溴盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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「同位素标记抑制剂」CAS:1258597-61-3|(Rac)-Apremilast-d5
作者：德尔塔生物 日期：2025-06-11
生物活性：(Rac)-Apremilast-d5 is a deuterium labeled (R)-Apremilast. (R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast[1].分子量：465.53Formula：C22H19D5N2O7SCAS 号：1258597-61-3非标记 CAS：608141-41-9中文名称：(Rac)-阿普司特-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (522 KB)产品使用指南 (1538 KB)参考文献[1]. Synthesis of Substituted β‐Functionalised Styrenes by Microwave‐Assisted Olefin
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「同位素标记抑制剂」CAS:1365986-73-7|Vemurafenib-d7
作者：德尔塔生物 日期：2025-06-11
生物活性：Vemurafenib-d7 is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Vemurafenib-d7 相关抗体:BRAF AntibodyPhospho-BRAF (Thr401) AntibodyA-RAF AntibodyB-Raf AntibodyRaf1 AntibodyRKIP Antibody (YA1869)A RAF Antibody (YA2673)分子量：496.97Formula：C23H11D7ClF2N3O3SCAS 号：1365986-73-7非标记 CAS：918504-65-1中文名称：维罗非尼-d7；维罗菲尼-d7；威罗菲尼-d7；唯罗非尼-d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (532 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Bollag G, et al. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature, 2010, 467(7315), 596-599. [Content Brief][3]. Yang H, et al. RG7204 (PLX4032), a selective BRAFV600E inhibitor, displays
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「同位素标记抑制剂」CAS:1323633-98-2|Fluphenazine-d8
作者：德尔塔生物 日期：2025-06-11
生物活性：Fluphenazine-d8 is the deuterium labeled Fluphenazine. Fluphenazine is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine blocks neuronal voltage-gated sodium channels. Fluphenazine acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibit SARS-CoV-2[1][2][3][4][5][6].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fluphenazine-d8 相关抗体:xCT Antibody (YA006)xCT Antibody (YA652)DRD2 AntibodyAlpha-ENaC AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)CRMP2 Antibody (YA3370)SLC12A1 Antibody (YA1403)CRMP1 Antibody (YA1941)CRMP5 Antibody (YA2497)CRMP3 Antibody (YA2563)CRMP4 Antibody (YA2777)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：445.57Formula：C22H18D8F3N3OSCAS 号：1323633-98-2非标记 CAS：69-23-8中文名称：氟奋乃静癸EP杂质B-d8
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「同位素标记抑制剂」CAS:1246815-00-8|Fenvalerate-d5
作者：德尔塔生物 日期：2025-06-11
生物活性：Fenvalerate-d5 is the deuterium labeled Fenvalerate. Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fenvalerate-d5 相关抗体:PFKFB3 AntibodyDUSP1 AntibodyDUSP3 AntibodyMRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Intestinal Alkaline Phosphatase Antibody (YA1559)PFKL Antibody (YA1597)SHP2 Antibody (YA1643)PP1C alpha/beta Antibody (YA1700)PTP1B Antibody (YA1776)PLEKHA1 Antibody (YA2145)PGAM1 Antibody (YA2156)DUSP6 Antibody (YA2280)PRAS40 Antibody (YA3179)PPP4C Antibody (YA687)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Phospho-PTP1B (Ser352) Antibody (YA1027)Phospho-PTP1B (Ser378) Antibody (YA1028)Placental Alkaline Phosphatase Antibody (YA1038)Placental Alkaline Phosphatase Antibody (YA1039)PP1C alpha Antibody (YA1040)PP1C alpha Antibody (YA1041)SHP1 Antibody (YA1044)SHP1 Antibody (YA1045)Anthrax Protective gen Antibody (YA1060)PP1C gamma Antibody (YA1068)PPP5C Antibody (YA1069)分子量：424.93Formula：C25H17D5ClNO3CAS 号：1246815-00-8非标记 CA
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「同位素标记抑制剂」CAS:1267657-68-0|Quinidine-d3
作者：德尔塔生物 日期：2025-06-11
生物活性：Quinidine-d3 is the deuterium labeled Quinidine. Quinidine is an antiarrhythmic agent for the treatment of abnormal heart rhythms and also malaria.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：327.44Formula：C20H21D3N2O2CAS 号：1267657-68-0非标记 CAS：56-54-2中文名称：奎尼丁 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (534 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Kehl SJ, et al. Quinidine-induced inhibition of the fast transient outward K+ current in rat melanotrophs. Br J Pharmacol. 1991 Jul;103(3):1807-13. [Content Brief][3]. Roden DM, et al. Class I antiarrhythmic agents: quinidine, procainamide and N-acetylprocainamide, disopyramide. [Content Brief][4]. Moody DE, et al. Quinidine inhibits in vivo metabolism of amphetamine in rats: impact upon correlation between GC/MS and immunoassay findings in rat urine. J Anal Toxicol. 1990 Sep-Oct;14(5):311-7. [Content Brief]
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「同位素标记抑制剂」CAS:172165-56-9|Acrivastine-d7
作者：德尔塔生物 日期：2025-06-11
生物活性：Acrivastine-d7 is a deuterium labeled Acrivastine. Acrivastine is a short acting histamine 1 receptor antagonist.分子量：355.48Formula：C22H17D7N2O2CAS 号：172165-56-9非标记 CAS：87848-99-5中文名称：阿伐斯汀 d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (496 KB)产品使用指南 (1538 KB)
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「同位素标记抑制剂」CAS:1356017-30-5|Imidapril-d3 hydrochloride
作者：德尔塔生物 日期：2025-06-11
生物活性：Imidapril-d3 (hydrochloride) (TA-6366-d3) is the deuterium labeled Imidapril hydrochloride. Imidapril hydrochloride (TA-6366) is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Imidapril-d3 hydrochloride 相关抗体:ACE2 AntibodyACE AntibodyACE Antibody (YA2094)分子量：444.92Formula：C20H25D3ClN3O6CAS 号：1356017-30-5非标记 CAS：89371-37-9中文名称：盐酸咪达普利 d3 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Moriya T, et al. Enhancement of swallowing motor activity by the ACE inhibitor imidapril in an arterially perfused rat preparation. Eur J Pharmacol. 2019;861:172601. [Content Brief]
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「同位素标记抑制剂」CAS:1188487-83-3|Nifuroxazide-d4
作者：德尔塔生物 日期：2025-06-11
生物活性：Nifuroxazide-d4 is the deuterium labeled Nifuroxazide. Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nifuroxazide-d4 相关抗体:FOXP3 Antibody (YA858)Phospho-STAT3 (Tyr705) Antibody (YA146)STAT3 Antibody (YA056)Phospho-STAT1 (Ser727) Antibody (YA148) Phospho-STAT1 (Tyr701) AntibodyPhospho-STAT3 (Tyr705) AntibodyFOXP3 AntibodyPhospho-STAT3 (Ser727) AntibodySTAT1 Antibody (YA059)STAT1 Antibody (YA667)STAT1 alpha AntibodySTAT2 Antibody (YA057)STAT5a AntibodySTAT5b AntibodySTAT6 AntibodyPhospho-STAT5 (Tyr694) Antibody (YA145)FOXP3 Antibody (YA759)Phospho-STAT1 (Ser727) Antibody (YA149) STAT3 Antibody (YA666)STAT4 AntibodySTAT5 AntibodyMRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Phospho-STAT5(Tyr694) Antibody (YA1513)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)T-bet / Tbx21 Antibody (YA1217)分子量：279.24Formula：C12H5D4N3O5CAS 号：1188487-83-3非标记 CAS：965-52-6中文名称：硝呋齐特 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please st
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