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「同位素标记抑制剂」CAS:2525175-25-9|12-HETE-d8

「同位素标记抑制剂」CAS:2525175-25-9|12-HETE-d8

作者:德尔塔生物 日期:2025-06-13

生物活性:12-HETE-d8 is the deuterium labeled 12-HETE. 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway[1].12-HETE has both anti-thrombotic and pro-thrombotic effects[2]. 12-HETE is a neuromodulator[3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.12-HETE-d8 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量:328.52Formula:C20H24D8O3CAS 号:2525175-25-9非标记 CAS:71030-37-0性状:液体颜色:Colorless to light yellow中文名称:12-羟基二十碳四烯酸-d8运输条件:Room tempe

「同位素标记抑制剂」CAS:327179-00-0|1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium

「同位素标记抑制剂」CAS:327179-00-0|1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium

作者:德尔塔生物 日期:2025-06-13

生物活性:1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 (sodium) is deuterium labeled 1,2-Dipalmitoyl-sn-glycerol 3-phosphate. 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:733.26Formula:C35H6D62NaO8PCAS 号:327179-00-0非标记 CAS:169051-60-9性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, protect from light, stored under nitrogen*In solvent : -80

「同位素标记抑制剂」CAS:478518-78-4|Galactose 1-phosphate-13C potassium

「同位素标记抑制剂」CAS:478518-78-4|Galactose 1-phosphate-13C potassium

作者:德尔塔生物 日期:2025-06-13

生物活性:Galactose 1-phosphate-13C (potassium) is the 13C labeled Galactose 1-phosphate Potassium salt. Galactose 1-phosphate Potassium salt is is an intermediate in the galactose metabolism and nucleotide sug[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Galactose 1-phosphate-13C potassium 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:337.31Formula:C513CH11K2O9PCAS 号:478518-78-4非标记 CAS:19046-60-7性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage,

「同位素标记抑制剂」CAS:2264050-65-7|Lenvatinib-d4

「同位素标记抑制剂」CAS:2264050-65-7|Lenvatinib-d4

作者:德尔塔生物 日期:2025-06-13

生物活性:Lenvatinib-d4 is the deuterium labeled Lenvatinib. Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Lenvatinib-d4 相关抗体:FGFR2/CD332 Antibodyc-Kit Antibody (YA502)Phospho-PDGFR beta (Y740) AntibodyVEGF Receptor 2 Antibody (YA014)FGFR1 AntibodyFGFR1 Oncogene Partner AntibodyFGFR2 AntibodyFGFR3 AntibodyPDGFR alpha AntibodyFGF2 AntibodyVEGF Receptor 1 AntibodyVEGFA AntibodyVEGF Receptor2 Antibody FGF1 Antibody (YA1430)PDGF B Antibody (YA1556)FGFR4 Antibody (YA1588)PLGF Antibody (YA1812)PDGFR beta Antibody (YA1925)VEGFD Antibody (YA2385)FGF19 Antibody (YA2672)TACC3 Antibody (YA2921)Phospho-PDGFR beta (Tyr740) Antibody (YA3062)FGF21 Antibody (YA3276)c-Kit AntibodySCF AntibodyPGF Antibody (YA1434)Neuropilin 1 Antibody (YA1831)VEGFB Antibody (YA2627)分子量:430.88Formula:C21H15D4ClN4O4CAS 号:2264050-65-7非标记 CAS:417716-92-8性状:固体颜色:Off-white to pink中文名称:乐伐替尼 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:2260670-15-1|Sphingosine-1-phosphate-d7

「同位素标记抑制剂」CAS:2260670-15-1|Sphingosine-1-phosphate-d7

作者:德尔塔生物 日期:2025-06-13

生物活性:Sphingosine-1-phosphate-d7 is the deuterium labeled Sphingosine-1-phosphate. Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors[1]. Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Sphingosine-1-phosphate-d7 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:386.51Formula:C18H31D7NO5PCAS 号:2260670-15-1非标记

「同位素标记抑制剂」CAS:946524-36-3|Oleoylethanolamide-d4

「同位素标记抑制剂」CAS:946524-36-3|Oleoylethanolamide-d4

作者:德尔塔生物 日期:2025-06-13

生物活性:Oleoylethanolamide-d4 is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Oleoylethanolamide-d4 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyPPAR alpha AntibodyMETTL3 AntibodyPPAR gamma AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)PPAR gamma Antibody (YA122)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin Antibody分子量:329.55Formula:C20H35D4NO2CAS 号:946524-36-3非标记 CAS:111-58-0性状:液体颜色:Colorless to light yellow运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Solution, -20°C, 2 years

「同位素标记抑制剂」CAS:1537187-53-3|Carfilzomib-d8

「同位素标记抑制剂」CAS:1537187-53-3|Carfilzomib-d8

作者:德尔塔生物 日期:2025-06-13

生物活性:Carfilzomib-d8 is deuterium labeled Carfilzomib. Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of 5 nM in ANBL-6 and RPMI 8226 cells.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Carfilzomib-d8 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyProteasome beta 8 Antibody (YA684)AIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase Antibody分子量:727.96Formula:C40H49D8N5O7CAS 号:1537187-53-3非标记 CAS:868540-17-4性状:固体颜色:White to off-white中文名称:卡非佐米-d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

「同位素标记抑制剂」CAS:1190006-03-1|Hydrochlorothiazid-13C,d2

「同位素标记抑制剂」CAS:1190006-03-1|Hydrochlorothiazid-13C,d2

作者:德尔塔生物 日期:2025-06-13

生物活性:Hydrochlorothiazid-13C,d2 is the 13C- and deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[71].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Hydrochlorothiazid-13C,d2 相关抗体:Smad3 AntibodyTGF beta 1 AntibodySmad1 AntibodySmad2 AntibodySmad4 AntibodySmad5 AntibodyPhospho-Smad3 (Ser423/Ser425) AntibodyATP1A1 AntibodyCD105 Antibody (YA547)Noggin Antibody (YA698)Phospho-Smad1 (Ser463/Ser465) AntibodyPhospho-Smad2 (Ser250) AntibodyPhospho-Smad3 (Ser423/425) AntibodySmad2/3 AntibodyInhibin beta A Antibody (YA2780)Phospho-Smad5 (Ser463/465) Antibody (YA2838)LGI1 Antibody (YA2885)Inhibin alpha Antibody (YA1232)Inhibin beta B Antibody (YA1677)Cardiac Troponin C Antibody (YA2125)Phospho-NDRG1 (Ser330) Antibody (YA2618)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)Kir2.1 Antibody (YA2871)SARA Antibody (YA3226)分子量:300.74Formula:C613CH6D2ClN3O4S2C

「同位素标记抑制剂」CAS:916979-34-5|Allopurinol-d2

「同位素标记抑制剂」CAS:916979-34-5|Allopurinol-d2

作者:德尔塔生物 日期:2025-06-13

生物活性:Allopurinol-d2 is deuterium labeled Allopurinol. Allopurinol is a potent xanthine oxidase inhibitor (IC50 values of 0.2 to 50 μM). Allopurinol can be used for the research of hyperuricemia and gout. Antileishmanial effect[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Allopurinol-d2 相关抗体:Xanthine Oxidase Antibody (YA1957)分子量:138.12Formula:C5H2D2N4OCAS 号:916979-34-5非标记 CAS:315-30-0性状:固体颜色:White to off-white中文名称:别嘌醇-d2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:1190007-20-5|Thiabendazole-d4

「同位素标记抑制剂」CAS:1190007-20-5|Thiabendazole-d4

作者:德尔塔生物 日期:2025-06-13

生物活性:Thiabendazole-d4 is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Thiabendazole-d4 相关抗体:Parkin AntibodyMCU AntibodyMitofusin 2 AntibodyLIAS AntibodyNDUFS8 Antibody (YA1352)TOMM20 Antibody (YA1380)NUDT9 Antibody (YA1453)CPS1 Antibody (YA1661)Complex III Subunit 5 Antibody (YA1865)NDUFB8 Antibody (YA1947)MFF Antibody (YA2012)NDUFS4 Antibody (YA2072)MT ND1 Antibody (YA2089)Mitochondrial Fission 1 Protein Antibody (YA2098)Cyclophilin 40 Antibody (YA2099)TIMM44 Antibody (YA2207)NDUFS1 Antibody (YA2535)CLPX Antibody (YA2814)MTCO2 Antibody (YA3254)Mitochondrial Ferritin Antibody (YA3353)mtTFA Antibody (YA3360)Mitofusin 1 AntibodyOrnithine Carbamoyltransferase/OTC Antibody (YA1230)NDUFB10 Antibody (YA1330)NDUFB11 Antibody (YA1331)NDUFB2 Antibody (YA1335)NDUFB4 Antibody (YA1338)NDUFB9 Antibody (YA1340)NDUFC2 Antibody (YA1343)NDUFS3 Antibody (YA1346)分子量:205.27Formula:C10H3D4N3SCAS 号:1190007-20-5非标记 CAS:148-79-8性状:固体颜色:White to off-white中文名称:噻菌灵-d4; 噻苯唑-d4; 噻苯咪唑-d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solve

「同位素标记抑制剂」CAS:548783-71-7|Fexofenadine-d6

「同位素标记抑制剂」CAS:548783-71-7|Fexofenadine-d6

作者:德尔塔生物 日期:2025-06-13

生物活性:Fexofenadine-d6 is deuterium labeled Fexofenadine, which is an antihistamine pharmaceutical agent.分子量:507.69Formula:C32H33D6NO4CAS 号:548783-71-7非标记 CAS:83799-24-0性状:固体颜色:White to off-white中文名称:非索非那定 d6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:352534-94-2|MES-d13

「同位素标记抑制剂」CAS:352534-94-2|MES-d13

作者:德尔塔生物 日期:2025-06-13

生物活性:MES-d13 is the deuterium labeled MES. MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.MES-d13 相关抗体:Mouse IgG Isotype Control6X His-tag (C-terminal) Antibody (YA860)DYKDDDDK Tag (FLAG) AntibodyGFP AntibodyMyc-tag AntibodyHA tag Antibody (YA856)GST-Tag Antibody HRP ConjugatedV5-tag AntibodyCollagen I alpha 2 AntibodyRabbit IgG Isotype Control6X His Tag (C-terminal) AntibodyHis Tag Antibody (HRP) (YA877)HA Tag Antibody (HRP) (YA876)EYFP Tag Antibody (YA872)HSV Tag Antibody (YA878)MBP Tag Antibody (YA879)RFP Tag Antibody (YA882)S Tag Antibody (YA883)SRT Tag Antibody (YA884)Strep-Tag II Antibody (YA885)TAP Tag Antibody (YA887)Collagen II AntibodyCollagen III AntibodyCollagen X AntibodyCollagen IV AntibodyCollagen I AntibodyCollagen VI alpha 1/2/3 Antibody (YA2637)AmCyan Tag Antibody (YA864)DsbA Tag Antibody (YA868)E2 Tag Antibody (YA870)分子量:208.32Formula:C6D13NO4SCAS 号:352534-94-2非标记 CAS

「同位素标记抑制剂」CAS:7325-17-9|Glycerol-d8

「同位素标记抑制剂」CAS:7325-17-9|Glycerol-d8

作者:德尔塔生物 日期:2025-06-13

生物活性:Glycerol-d8 is the deuterium labeled Glycerol[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:100.14Formula:C3D8O3CAS 号:7325-17-9性状:液体颜色:Colorless to light yellow运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Pure form-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:148706-06-3|4-Hydroxynonenal-d3

「同位素标记抑制剂」CAS:148706-06-3|4-Hydroxynonenal-d3

作者:德尔塔生物 日期:2025-06-13

生物活性:4-Hydroxynonenal-d3 is the deuterium labeled 4-Hydroxynonenal. 4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria[1][2][3].IC50 & Target:ALDH2体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.4-Hydroxynonenal-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)ALDH1A1 AntibodyAsparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibo

「同位素标记抑制剂」CAS:1216678-68-0|Mirtazapine-d3

「同位素标记抑制剂」CAS:1216678-68-0|Mirtazapine-d3

作者:德尔塔生物 日期:2025-06-13

生物活性:Mirtazapine-d3 is a deuterium labeled Mirtazapine. Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors[1].IC50 & Target[1]:5-HT2 Receptor5-HT3 Receptor体内研究(In Vivo)米氮平 (腹膜内注射;10-50 mg/Kg;14 天) 处理可使心率、呼吸率、焦虑水平正常化并消除在 MeCP2 缺失小鼠中观察到的跳跃行为,从而改善表型评分[2]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Animal Model:MeCP2 null mice[2]Dosage:10-50 mg/KgAdministration:Intraperitoneal injection; 10-50 mg/Kg; 14 daysResult:Restored the thickness of MeCP2-null mice somatosensory cortex, especially of layers II-III and VI.分子量:268.38Formula:C17H16D3N3CAS 号:1216678-68-0非标记 CAS:85650-52-8性状:固体颜色:White to off-white中文名称:米氮平杂质13 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month