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Artesunate-d3,青蒿酯 d3「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Artesunate-d3 is the deuterium labeled Artesunate. Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1).体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Artesunate-d3 相关抗体:FOXP3 Antibody (YA858)S100A10 Antibody (YA675)Ferritin Heavy Chain AntibodyPhospho-STAT3 (Tyr705) Antibody (YA146)STAT3 Antibody (YA056)Phospho-STAT1 (Ser727) Antibody (YA148) Phospho-STAT1 (Tyr701) AntibodyPhospho-STAT3 (Tyr705) AntibodyFOXP3 AntibodyPhospho-STAT3 (Ser727) AntibodySTAT1 Antibody (YA059)STAT1 Antibody (YA667)STAT1 alpha AntibodySTAT2 Antibody (YA057)STAT5a AntibodySTAT5b AntibodySTAT6 AntibodyPhospho-STAT5 (Tyr694) Antibody (YA145)FOXP3 Antibody (YA759)AMID/FSP1 AntibodyPeroxiredoxin 1 Antibody (YA692)Phospho-STAT1 (Ser727) Antibody (YA149) STAT3 Antibody (YA666)STAT4 AntibodySTAT5 AntibodyPRDX3 Antibody (YA909)Phospho-STAT5(Tyr694) Antibody (YA1513)Ferritin Light Chain Antibody (YA971)Ferritin Light Chain Antibody (YA972)T-bet / Tbx21 Antibody (YA1217)分子量:387.44Formula:C19H25D3O8CAS 号:1316303-44-2非标记 CAS:88495-63-0中文名称:青蒿酯 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certif
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Caffeic acid-13C3,咖啡酸-13C3; 3,4-Dihydroxycinnamic acid-13C3「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Caffeic acid-13C3 is an 13C labeled caffeic acid. Caffeic acid is a phytonutrient belonging to the flavonoids. Caffeic acid and its derivatives, are potential antimicrobial agents, chronic infection induced by microbes such as bacteria, fungi, and viruses[1].分子量:183.14Formula:C613C3H8O4CAS 号:1185245-82-2非标记 CAS:331-39-5中文名称:咖啡酸-13C3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (522 KB)产品使用指南 (1538 KB)参考文献[1]. Khan F, et al. Caffeic Acid and Its Derivatives: Antimicrobial Drugs toward Microbial Pathogens. J Agric Food Chem. 2021 Mar 17;69(10):2979-3004. [Content Brief]
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Stigmasterol-d5-1,豆甾醇-d5; Stigmasterin-d5-1「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Stigmasterol-d5-1 is deuterium labeled Stigmasterol. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Stigmasterol-d5-1 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyMMP3 AntibodyMMP12 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)TIMP2 AntibodyMMP9 Antibody (YA285)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)MMP2 AntibodyAsparagine Synthetase AntibodyCalnexin Antibody分子量:417.72Formula:C29H43D5OCAS 号:2260669-29-0非标记 CAS:83-48-7中文名称:豆甾醇-d5-1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Gaba
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Coenzyme Q10-d6,辅酶Q10-d6; CoQ10-d6; Ubiquinone-10-d6「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Coenzyme Q10-d6 is deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Coenzyme Q10-d6 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Catalase Antibody (YA552)Catalase Antibody (YA811)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyAMID/FSP1 AntibodyKi67 Antibody (YA001)分子量:869.38Formula:C59H84D6O4CAS 号:110971-02-3非标记 CAS:303-98-0中文名称:辅酶Q10-d6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium
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4-?Hydroxy-?3-?methoxy benzaldehyde-?d3,香兰素-d3;香草醛-d3「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:4- Hydroxy- 3- methoxy benzaldehyde- d3 is the deuterium labeled Vanillin[1]. Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine[2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.4-?Hydroxy-?3-?methoxy benzaldehyde-?d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:155.17Formula:C8H5D3O3CAS 号:74495-74-2非标记 CAS:121-33-5中文名称:香兰素-d3;香草醛-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料D
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Mabuterol-d9,马布特罗-d9「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Mabuterol-d9 is a deuterium labeled Mabuterol. Mabuterol is an agonist of the β2-adrenergic receptor[1].IC50 & Target:β adrenergic receptor分子量:319.80Formula:C13H9D9ClF3N2OCAS 号:1246819-58-8非标记 CAS:56341-08-3中文名称:马布特罗-d9运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)产品使用指南 (1538 KB)参考文献[1]. J Kim, et al. [The role of beta 2-adrenoceptor on the pathogenesis of insulin resistance in essential hypertension]. Nihon Naibunpi Gakkai Zasshi. 1994 Jun 20;70(5):521-8. [Content Brief]
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Montelukast-d6,MK0476-d6 free acid「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Montelukast-d6 is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Montelukast-d6 相关抗体:Leukotriene A4 Hydrolase Antibody (YA2400)分子量:592.22Formula:C35H30D6ClNO3SCAS 号:1093746-29-2非标记 CAS:158966-92-8中文名称:孟鲁司特钠 d6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (533 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Pu S, et, al. Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury. Front Pharmacol. 2019 Sep 18; 10:1070.;William RHJ, et, al. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am
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7-Ethoxycoumarin-d5「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:7-Ethoxycoumarin-d5 is deuterium labeled 7-Ethoxycoumarin. 7-Ethoxycoumarin is a substrate for cytochrome P450(CYP450) and has been used in the functional characterization of various CYPs[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.7-Ethoxycoumarin-d5 相关抗体:Cytochrome C AntibodyCytochrome P450 17A1 AntibodyAromatase AntibodyCYP11A1 AntibodyCytochrome P450 1B1 Antibody (YA1836)Adrenodoxin Antibody (YA2005)Cytochrome P450 27A1 Antibody (YA2163)Cytochrome P450 2C9 Antibody (YA2166)Cytochrome P450 2E1 Antibody (YA2302)Cytochrome P450 Reductase Antibody (YA2619)Thromboxane A Synthase Antibody (YA2670)Cytochrome P450 3A4 Antibody (YA3365)HSD11B1 Antibody (YA3376)Cytochrome P450 17A1 Antibody (YA786)CYP2E1 AntibodyCYP1A2 AntibodyPLSCR3 Antibody (YA1672)PROX1 Antibody (YA1754)Cytochrome P450 4A Antibody (YA2087)Cytochrome P450 24A1 Antibody (YA2121)Cytochrome P450 26A1 Antibody (YA2259)COX5B Antibody (YA2550)Steroidogenic Factor 1 Antibody (YA3166)Dynein Light Chain Tctex Type 1 Antibody (YA3263)Cytochrome P450 2D6 Antibody (YA3384)分子量:195.23Formula:C11H5D5O3CAS 号:1189956-39-5非标记 CAS:31005-02-4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store th
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Vinpocetine-d5,长春西汀 d5「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Vinpocetine-d5 is the deuterium labeled Vinpocetine. Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Vinpocetine-d5 相关抗体:Phospho-IKB alpha (Ser32) Antibody (YA183)TBK1 Antibody (YA662)IKK beta AntibodyTBK1 Antibody (YA040)xCT Antibody (YA006)IKK alpha AntibodyIKK alpha + IKK beta AntibodyIKK gamma AntibodyxCT Antibody (YA652)IKB alpha AntibodyPhospho-IKB alpha (Ser32) Antibody (YA185)Phospho-IKB alpha (Ser36) AntibodyAlpha-ENaC AntibodyPDE1B Antibody (YA1553)IKK alpha/beta Antibody (YA1871)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)CRMP2 Antibody (YA3370)SLC12A1 Antibody (YA1403)IKK epsilon Antibody (YA1611)PDE4D Antibody (YA1714)CRMP1 Antibody (YA1941)TAB1 Antibody (YA1951)CRMP5 Antibody (YA2497)CRMP3 Antibody (YA2563)CRMP4 Antibody (YA2777)IKB epsilon An
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Benzo[e]pyrene-d12「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Benzo[e]pyrene-d12 is the deuterium labeled Benzo[e]pyrene[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:264.38Formula:C20D12CAS 号:205440-82-0运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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NVP-BEZ 235-d3「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:NVP-BEZ 235-d3 is the deuterium labeled NVP-BEZ 235[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:472.56Formula:C30H20D3N5OCAS 号:1133206-74-2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (522 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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Tiagabine-methyl-d6 hydrochloride「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Tiagabine-methyl-d6 (hydrochloride) is the deuterium labeled Tiagabine-methyl hydrochloride[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:418.05Formula:C20H20D6ClNO2S2CAS 号:1217808-68-8非标记 CAS:145821-59-6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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Dolutegravir-d5,度鲁特韦-d5; S/GSK1349572-d5「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Dolutegravir-d5 is deuterium labeled Dolutegravir. Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM)[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Dolutegravir-d5 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)Tat SF1 Antibody (YA2886)分子量:424.41Formula:C20H14D5F2N3O5CAS 号:2249814-82-0非标记 CAS:1051375-16-6中文名称:度鲁特韦-d5;德罗特韦-d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (533 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Kobayashi M, et al. In Vit
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Granisetron-d3 (1-methyl-d3,替比夫定-d3「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Granisetron-d3 (1-methyl-d3) is the deuterium labeled Granisetron[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:315.43Formula:C18H21D3N4OCAS 号:1224925-76-1非标记 CAS:109889-09-0中文名称:替比夫定-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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Ambrisentan-d10,安倍生坦-d10; BSF 208075-d10; LU 208075-d10「同位素标记抑制剂」
作者:德尔塔生物 日期:2025-08-13
生物活性:Ambrisentan-d10 (BSF 208075-d10; LU 208075-d10) is the deuterium labled Ambrisentan (HY-13209). Ambrisentan is a selective ET type A receptor (ETAR) antagonist.体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:388.48Formula:C22H12D10N2O4CAS 号:1046116-27-1非标记 CAS:177036-94-1中文名称:安倍生坦-d10; 安立生坦-d10运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Okamoto T, et al. Antifibrotic effects of Ambrisentan, an endothelin-A receptor antagonist, in a non-alcoholic steatohepatitis mouse model. World J Hepatol. 2016 Aug 8;8(22):933-41. [Content Brief][2]. Lisk C, et al. Nrf2 activation: a potential strategy for the prevention of acute mountain sickness. Free Radic Biol Med. 2013 Oct;63:264-73. [Content Brief][3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]