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「同位素标记抑制剂」AICAR-13C2,15N
作者：德尔塔生物 日期：2025-09-19
生物活性：AICAR-13C2,15N (Acadesine-13C2,15N; AICA Riboside-13C2,15N) is the 13C and 15N labeled AICAR (HY-13417)[1]. AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor[2][3].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.AICAR-13C2,15N 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyYAP1 AntibodyAMPK alpha AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyPhospho-AMPK alpha 2 (Thr172) AntibodyPhospho-YAP1 (Ser127) Antibody (YA136)METTL3 AntibodyAMPK alpha 2 Antibody (YA833)Phospho-AMPK alpha 2(Ser345) AntibodyAMPK alpha 1 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)AMPK alpha 1 Antibody (YA624)Laminin beta 1 AntibodyPhospho-AMPK alpha 1 (Ser496) Antibody (YA226)Phospho-Hormone sensitive lipase (Ser853) Antibody分子量：261.21Formula：C713C2H14N315NO5CAS 号：1609374-70-0非标记 CAS：2627-69-2中文名称：阿卡地新-13C2,15N运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended condit
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「同位素标记抑制剂」Bisphenol Z-d6
作者：德尔塔生物 日期：2025-09-19
生物活性：Bisphenol Z-d6 is the deuterium labeled 4,4'-(Cyclohexane-1,1-diyl)diphenol (HY-W013326)[1].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：274.39Formula：C18H14D6O2CAS 号：2733972-12-6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (534 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」Acesulfame-d4 potassium
作者：德尔塔生物 日期：2025-09-19
生物活性：Acesulfame-d4 potassium is the deuterium labeled Acesulfame (potassium) (HY-D0195)[1]. Acesulfame potassium is an artificial sweetener. Acesulfame potassium (long-term) affects cognitive functions, potentially via altering neuro-metabolic functions in mice[2].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Acesulfame-d4 potassium 相关抗体:Mouse IgG Isotype Control6X His-tag (C-terminal) Antibody (YA860)DYKDDDDK Tag (FLAG) AntibodyGFP AntibodyMyc-tag AntibodyHA tag Antibody (YA856)GST-Tag Antibody HRP ConjugatedV5-tag AntibodyCollagen I alpha 2 AntibodyRabbit IgG Isotype Control6X His Tag (C-terminal) AntibodyHis Tag Antibody (HRP) (YA877)HA Tag Antibody (HRP) (YA876)EYFP Tag Antibody (YA872)HSV Tag Antibody (YA878)MBP Tag Antibody (YA879)RFP Tag Antibody (YA882)S Tag Antibody (YA883)SRT Tag Antibody (YA884)Strep-Tag II Antibody (YA885)TAP Tag Antibody (YA887)Collagen II AntibodyCollagen III AntibodyCollagen X AntibodyCollagen IV AntibodyCollagen I AntibodyCollagen VI alpha 1/2/3 Antibody (YA2637)AmCyan Tag Antibody (YA864)DsbA Tag Antibody (YA868)E2 Tag Antibody (YA870)分子量：205.27Formula：C4D4KNO4SCAS 号：1623054-53-4非标记 CAS：55589-62-3中文名称：乙酰舒泛钾-d4； 安塞蜜-d4； 乙酰磺胺酸钾-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate
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「同位素标记抑制剂」Enasidenib-d6
作者：德尔塔生物 日期：2025-09-19
生物活性：Enasidenib-d6 (AG-221-d6) is the deuterium labeled Enasidenib (HY-18690)[1]. Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively[2].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Enasidenib-d6 相关抗体:IDH1 AntibodyAconitase 2 Antibody (YA2151)Aconitase 1 Antibody (YA2850)分子量：479.41Formula：C19H11D6F6N7OCAS 号：2095569-76-7非标记 CAS：1446502-11-9中文名称：恩西地平-d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」Pomalidomide-d5
作者：德尔塔生物 日期：2025-09-19
生物活性：Pomalidomide-d5 is deuterium labeled Pomalidomide. Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors.IC50 & Target：Cereblon体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pomalidomide-d5 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量：278.27Formula：C13H6D5N3O4CAS 号：1377838-49-7非标记 CAS：19171-19-8中文名称：泊马度胺-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Dat
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「同位素标记抑制剂」Benazepril-d5 hydrochloride
作者：德尔塔生物 日期：2025-09-19
生物活性：Benazepril-d5 hydrochloride is deuterium labeled Benazepril hydrochloride. Benazepril hydrochloride is an orally active angiotensin-converting enzyme (ACE) inhibitor to reduce angiotensin-II production. Benazepril hydrochloride inhibits oxidative stress and inhibits apoptosis by the PI3K/Akt signaling pathway. In addition, Benazepril hydrochloride improves diabetic nephropathy and decreases proteinuria. Benazepril hydrochloride can be used in the study of hypertension, heart failure and diabetic nephropathy[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Benazepril-d5 hydrochloride 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)Phospho-AKT1 (Ser473) AntibodyAKT1/2/3 Antibody (YA633)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyPhospho-AKT (Thr308) AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyPhospho-AKT1(Ser473) Antibodyc-Myc AntibodyCyclin E1 AntibodyACE2 AntibodyAIF Antibody (YA636)AKT1 Antibody (YA834)AKT1 Antibody (YA634)ALIX AntibodyCatalase Antibody (YA552)Catalase Antibody (YA811)CNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cy
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「同位素标记抑制剂」Tilmicosin-d3
作者：德尔塔生物 日期：2025-09-19
生物活性：Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Tilmicosin-d3 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)iNOS AntibodyDYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase Antibody分子量：872.15Formula：C46H77D3N2O13CAS 号：2714486-61-8非标记 CAS：108050-54-0性状：固体颜色：
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「同位素标记抑制剂」Leriglitazone-d4
作者：德尔塔生物 日期：2025-09-19
生物活性：Leriglitazone-d4 (MIN-102-d4; Hydroxypioglitazone-d4) is deuterium labeled Leriglitazone. Leriglitazone is an orally active and a BBB-penatrable PPARγ agonist with an EC50 of 9 μM. Leriglitazone, as a regulator of mitochondrial function, has neuroprotective, anti-inflammatory and antioxidant effects. Leriglitazone can be used in the study of neuroinflammatory and neurodegenerative diseases[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Leriglitazone-d4 相关抗体:PPAR alpha AntibodyPPAR gamma AntibodyPPAR gamma Antibody (YA122)PGC1 beta Antibody (YA1411)分子量：376.46Formula：C19H16D4N2O4SCAS 号：1188263-49-1非标记 CAS：146062-44-4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Mosure SA,et al. Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPARγ Drug Pioglitazone. J Med Chem. 2019 Feb 28;62(4):200
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「同位素标记抑制剂」Zilpaterol-d7
作者：德尔塔生物 日期：2025-09-19
生物活性：Zilpaterol-d7 is a deuterium Zilpaterol. Zilpaterol is a β-adrenergic agonist that have been widely used to feed cattle[1].IC50 & Target：β adrenergic receptor体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Zilpaterol-d7 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：268.36Formula：C14H12D7N3O2CAS 号：1217818-36-4非标记 CAS：119520-05-7中文名称：齐帕特罗-d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (540 KB)产品使用指南 (1538 KB)参考文献[1]. Piña-Olmos S, et al. Extracellular and intracellular zilpaterol and clenbuterol quantification in Hep G2 liver cells by UPLC-PDA and UPLC-MS/MS. J Pharm Biomed Anal. 2021 Feb 20;195:113817. [Content Brief][2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」5-PAHSA-d9
作者：德尔塔生物 日期：2025-09-19
生物活性：5-PAHSA-d9 is the deuterium labeled 5-PAHSA (HY-116193). 5-PAHSA is a kind of anti-inflammatory and antidiabetic lipokines that connect glucose and lipid metabolism[1].分子量：547.94Formula：C34H57D9O4CAS 号：1809226-17-2非标记 CAS：1481636-41-2运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (515 KB)产品使用指南 (1538 KB)参考文献[1]. Veronika Paluchova, et al. Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice. Diabetes. 2020 Mar;69(3):300-312. [Content Brief]
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「同位素标记抑制剂」Hydroxyzine-d8
作者：德尔塔生物 日期：2025-09-19
生物活性：Hydroxyzine-d8 is deuterium labeled Hydroxyzine. Hydroxyzine is a histamine H1-receptor antagonist[1].IC50 & Target：H1 Receptor分子量：382.95Formula：C21H19D8ClN2O2CAS 号：1189480-47-4非标记 CAS：68-88-2性状：固体颜色：White to off-white中文名称：羟嗪-d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Lamotrigine-13C3
作者：德尔塔生物 日期：2025-09-19
生物活性：Lamotrigine-13C3 is the 13C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3]德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Lamotrigine-13C3 相关抗体:xCT Antibody (YA006)xCT Antibody (YA652)Alpha-ENaC AntibodyCRMP2 Antibody (YA3370)SLC12A1 Antibody (YA1403)CRMP1 Antibody (YA1941)CRMP5 Antibody (YA2497)CRMP3 Antibody (YA2563)CRMP4 Antibody (YA2777)分子量：259.07Formula：C613C3H7Cl2N5CAS 号：1188265-38-4非标记 CAS：84057-84-1性状：固体颜色：White to off-white中文名称：拉莫三嗪-13C3；那蒙特金-13C3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (536 KB)产品使用指南 (1538 KB)参考文献[1]. M J Leach, et al. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. Epilepsia. Sep-Oct 1986;27(5):490-7. [Content Brief][
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「同位素标记抑制剂」Azathioprine-13C4
作者：德尔塔生物 日期：2025-09-19
生物活性：Azathioprine-13C4 (BW 57-322-13C4) is the 13C labeled Azathioprine (HY-B0256). Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis[1][2][3].Clinical TrialNCT NumberSponsorConditionStart DatePhaseNCT00753103University Hospital Birmingham NHS Foundation TrustWegener´s Granulomatosis|Renal Limited Vasculitis|Microscopic PolyangiitisJanuary 2003Phase 2NCT01817972Gastroenterology Research of America|UCB PharmaCrohn´s DiseaseMarch 2013Phase 3NCT01446211Nordic Pharma SASWegeners GranulomatosisNovember 2011Phase 3 NCT00052039InterMuneLung Disease|Pulmonary FibrosisApril 2002Phase 3NCT04469842Vanderbilt University Medical Center|Veloxis PharmaceuticalsLung Transplant; ComplicationsAugust 2023Early Phase 1NCT03250143Postgraduate Institute of Medical Education and ResearchChronic Refractory UrticariaDecember 6, 2016Phase 1|Phase 2NCT01381432GlaxoSmithKlineLiver DiseasesDecember 2004NCT01941095Hoffmann-La RocheRheumatoid ArthritisNovember 20, 2013Phase 3NCT01056237Zhi-Hong Liu, M.D.|Nanjing University School of MedicineLupus NephritisFebruary 2010Not ApplicableNCT00461825Poitiers University HospitalKidney TransplantationJuly 1998Phase 3NCT03164473Assistance Publique - Hôpitaux de Paris|French Vasculitis Study GroupEosinophilic Granulomatosis With PolyangiitisMarch 7, 2018Phase 3NCT00400075Hospices Civils de LyonPolyarteritis Nodosa|Microscopic PolyangiitisJuly 1996Phase 4NCT00774852National Institute of Aller
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「同位素标记抑制剂」(Rac)-Paclobutrazol-15N3
作者：德尔塔生物 日期：2025-09-19
生物活性：(Rac)-Paclobutrazol-15N3 is the 15N-labeled Rac-Paclobutrazol[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(Rac)-Paclobutrazol-15N3 相关抗体:SDHA Antibody分子量：296.77Formula：C15H20Cl15N3OCAS 号：2642083-16-5非标记 CAS：76738-62-0中文名称：(Rac)-多效唑-15N3；(Rac)-氯丁唑-15N3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」Cyclobenzaprine-13C,d3 hydrochloride
作者：德尔塔生物 日期：2025-09-19
生物活性：Cyclobenzaprine-13C,d3 (hydrochloride) is the 13C- and deuterium labeled Cyclobenzaprine (hydrochloride).体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[60].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cyclobenzaprine-13C,d3 hydrochloride 相关抗体:MTNR1A Antibody分子量：315.86Formula：C1913CH19D3ClNCAS 号：1261394-10-8非标记 CAS：6202-23-9中文名称：阿米替林EP杂质B-13C,d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief][2]. Kobayashi, H., Y. Hasegawa, and H. Ono, Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems. Eur J Pharmacol, 1996. 311(1): p. 29-35. [Content Brief][3]. Honda, M., T. Nishida, and H. Ono, Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors. Eur J Pharmacol, 2003. 458(1-2): p. 91-9. [Content Brief]
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