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Carbon-13C，多壁碳纳米管(工业级-13C「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Carbon-13C is the 13C labeled Carbon[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：13.00Formula：13CCAS 号：14762-74-4性状：固体颜色：Dark gray to black中文名称：多壁碳纳米管(工业级)-13C运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)纯度 & 产品资料纯度： 97.10%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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Ethyl acetoacetate-d3，乙酰乙酸乙酯-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Ethyl acetoacetate-d3 is the deuterium labeled Ethyl acetoacetate. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds[1][2][3]. Ethyl acetoacetate is an inhibitor of bacterial biofilm[4].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[5].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ethyl acetoacetate-d3 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：133.16Formula：C6H7D3O3CAS 号：1565868-21-4性状：液体颜色：Colorless to light yellow中文名称：乙酰乙酸乙酯-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Butylated hydroxytoluene-d3，2,6-二叔丁基对甲酚-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Butylated hydroxytoluene-d3 is the deuterium labeled Butylated hydroxytoluene[1]. Butylated hydroxytoluene is an antioxidant widely used in foods and in food-related products[2]. Butylated hydroxytoluene is a Ferroptosis inhibitor[3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Butylated hydroxytoluene-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyAMID/FSP1 AntibodyKi67 Antibody (YA001)Osteopontin AntibodyPeroxiredoxin 1 Antibody (YA692)分子量：223.37Formula：C15H21D3OCAS 号：86819-59-2性状：固体颜色：White to yellow中文名称：2,6-二叔丁基对甲酚-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Levoglucosan-d7，1,6-Anhydro-β-D-glucopyranose-d7; 1,6-Anhydro-β-D-glucose-d7「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Levoglucosan-d7 is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Levoglucosan-d7 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：169.18Formula：C6H3D7O5CAS 号：2483832-05-7性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Curcumin-d6，Diferuloylmethane-d6; Natural Yellow 3-d6; Turmeric yellow-d6「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Curcumin-d6is a deuterium labeled Curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase (HATs) and also shows inhibitory effects on NF-κB and MAPKs.IC50 & Target：CBP/p300分子量：374.42Formula：C21H14D6O6CAS 号：1246833-26-0非标记 CAS：458-37-7性状：固体颜色：Yellow to orange中文名称：姜黄素 d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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2-Iodoacetamide-d4，Iodoacetamide-d4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：2-Iodoacetamide-d4 is the deuterium labeled 2-Iodoacetamide[1]. 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.2-Iodoacetamide-d4 相关抗体:FANCA Antibody (YA2112)FANCD2 Antibody (YA3102)FANCB Antibody (YA2804)分子量：188.99Formula：C2D4INOCAS 号：1219802-64-8非标记 CAS：144-48-9性状：固体颜色：White to off-white中文名称：碘乙酰胺-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Bumetanide-d5，布美他尼 d5「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Bumetanide-d5 is a deuterium labeled Bumetanide. Bumetanide is a selective Na+-K+-Cl- (NKCC1) inhibitor, weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively[1].分子量：369.45Formula：C17H15D5N2O5SCAS 号：1216739-35-3非标记 CAS：28395-03-1性状：固体颜色：White to off-white中文名称：布美他尼 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Agomelatine-d6，S-20098-d6「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Agomelatine-d6 is deuterium labeled Agomelatine. Agomelatine is a specific agonist of MT1 and MT2 receptors[1] .IC50 & Target：MT2MT1分子量：249.34Formula：C15H11D6NO2CAS 号：1079389-42-6非标记 CAS：138112-76-2性状：固体颜色：Off-white to light yellow中文名称：阿戈美拉汀 d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Ribociclib-d8，LEE011-d8「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Ribociclib-d8 is the deuterium labeled Ribociclib[1]. Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ribociclib-d8 相关抗体:Cyclin E1 Antibody (YA483)CD133 AntibodyCdk2 AntibodyCdk4 AntibodyCdk5 AntibodyCdk6 AntibodyCyclin D3 AntibodyCdk7 AntibodyCDK16 AntibodyCDK5 Antibody (YA796)CDK9 AntibodyCDKN2A/p16INK4a Antibody (YA508)Phospho-CDK1 (Tyr15) AntibodyPhospho-CDK1/2/3 (Thr14) AntibodyPhospho-CDK2 (Tyr15) AntibodyPhospho-Cyclin B1 (Ser126) AntibodyCDKN2A/p16INK4a AntibodyCDKN2C AntibodyPhospho-CDC6 (Ser54) Antibody (YA1017)Cyclin E2 Antibody (YA2594)CDC25C Antibody (YA2624)CDC6 Antibody (YA2626)CDC40 Antibody (YA3168)Cyclin A1/A2 Antibody (YA3336)CRK Antibody (YA790)Cyclin H Antibody (YA788)Cyclin H AntibodyPhospho-CDC6 (Ser106) Antibody (YA1016)CDC7 Antibody (YA1152)Cyclin D3/CCND3 Antibody (YA1201)分子量：442.59Formula：C23H22D8N8OCAS 号：2167898-24-8非标记 CAS：1211441-98-3性状：固体颜色：Off-white to light yellow中文名称：瑞博西尼-d8；瑞柏司可里布-d8运输条件：Room temperature in continental US; may vary elsewhere
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Olanzapine-d3，奥氮平 D3; LY170053-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Olanzapine-d3 is the deuterium labeled Olanzapine. Olanzapine is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM). Olanzapine is an atypical antipsychotic[1][2].IC50 & Target：D3 ReceptormAChR1分子量：315.45Formula：C17H17D3N4SCAS 号：786686-79-1非标记 CAS：132539-06-1性状：固体颜色：White to yellow中文名称：奥氮平 d3；奥兰氮平 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1304096-50-1|PLX-4720-d7
作者：德尔塔生物 日期：2025-09-17
生物活性：PLX-4720-d7 is the deuterium labeled PLX-4720. PLX-4720 is a potent and selective inhibitor of B-RafV600E with an IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.PLX-4720-d7 相关抗体:BRAF AntibodyPhospho-BRAF (Thr401) AntibodyA-RAF AntibodyB-Raf AntibodyRaf1 AntibodyRKIP Antibody (YA1869)A RAF Antibody (YA2673)分子量：420.87Formula：C17H7D7ClF2N3O3SCAS 号：1304096-50-1非标记 CAS：918505-84-7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Tsai J, et al. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A, 2008, 105(8), 3041-3046. [Content Brief][3]. Paraiso KH, et al. PTEN loss confers BRAF inhibitor resistance to melanoma cells through the sup
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CAS:1216885-36-7|Fmoc-Aib-OH-d3
作者：德尔塔生物 日期：2025-09-17
生物活性：Fmoc-Aib-OH-d3 is the deuterium labeled Trifloxystrobin. Trifloxystrobin (CGA 279202) is a fungicide, with EC50s of 23.0 μg/L and 1.7 μg/L for Daphnia magna neonate and embryos, respectively, after treatment for 48 h[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：328.38Formula：C19H16D3NO4CAS 号：1216885-36-7非标记 CAS：94744-50-0运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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CAS:1217720-20-1|rel-Ritonavir-d6，利托那韦-d6; rel-ABT 538-d6; rel-RTV-d6
作者：德尔塔生物 日期：2025-09-17
生物活性：rel-Ritonavir-d6 (rel-ABT 538-d6) is the deuterium labeled rel-Ritonavir. rel-Ritonavir is a relative configuration of Ritonavir (HY-90001). Ritonavir (ABT 538) is an inhibitor of HIV protease used to study of HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM[1][2].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。 氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：726.98Formula：C37H42D6N6O5S2CAS 号：1217720-20-1非标记 CAS：155213-67-5性状：固体颜色：Off-white to light yellow中文名称：rel-利托那韦-d6；rel-瑞托纳韦-d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1217675-13-2|Lubiprostone-d7，RU-0211-d7; SPI-0211-d7
作者：德尔塔生物 日期：2025-09-17
生物活性：Lubiprostone-d7 (RU-0211-d7) is the deuterium labeled Lubiprostone. Lubiprostone (SPI-0211) increases intestinal fluid secretion through generation of CIC-2/CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Lubiprostone-d7 相关抗体:GPX4 AntibodyiNOS AntibodyTNF alpha AntibodyGlutathione Peroxidase 4 AntibodyTNF Receptor 2 AntibodyCD40 AntibodyCD40L AntibodyDR5 AntibodyGPX1 AntibodynNOS AntibodyGlutathione Peroxidase 1 Antibody (YA404)Calumenin Antibody (YA813)eNOS AntibodyPhospho-eNOS (Ser1177) AntibodyMPO AntibodyDDAH2 Antibody (YA1447)TNFAIP3 Antibody (YA2231)TRADD Antibody (YA2276)DcR2 Antibody (YA2588)TNFRSF10B Antibody (YA660)Anoctamin 1 Antibody4-1BB Ligand Antibody (YA1329)GITR Antibody (YA1333)BAFFR Antibody (YA1356)BCMA Antibody (YA1501)4-1BB Antibody (YA1506)TNFSF12 Antibody (YA1507)BAFF Antibody (YA1510)LIGHT Antibody (YA1512)GITR-L Antibody (YA1515)分子量：397.51Formula：C20H25D7F2O5CAS 号：1217675-13-2非标记 CAS：136790-76-6中文名称：鲁比前列酮 d7
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CAS:1190043-69-6|Naratriptan-d3，GR-85548A-d3-1
作者：德尔塔生物 日期：2025-09-17
生物活性：Naratriptan-d3 (GR-85548A-d3) is the deuterium labeled Naratriptan (HY-B0197). Naratriptan is a selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC50=0.11 μM for dog basilar artery). Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms[1][2][3][4][5].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物研发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而备受关注[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Naratriptan-d3 相关抗体:MTNR1A Antibody分子量：338.48Formula：C17H22D3N3O2SCAS 号：1190043-69-6非标记 CAS：121679-13-8中文名称：那拉曲坦-d3；纳拉曲坦-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (545 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Rhoden E, et al. Anti-poliovirus activity of protease inhibitor AG-7404, and assessment of in vitro activity in combination with antiviral capsid inhibitor compounds. Antiviral Res. 2013 May;98(2):186-91.
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