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「同位素标记抑制剂」CAS:1781843-10-4|1'-Hydroxymidazolam-d4
作者：德尔塔生物 日期：2025-10-21
生物活性：1'-Hydroxymidazolam-d4 is the deuterium labeled 1'-Hydroxymidazolam. 1'-Hydroxymidazolam is a primary active metabolite of Midazolam, and it is a neuronal depressant agent. 1'-Hydroxymidazolam could inhibit neuronal activity add to the effects of Midazolam[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.1'-Hydroxymidazolam-d4 相关抗体:FMO3 Antibody (YA1992)分子量：345.79Formula：C18H9D4ClFN3OCAS 号：1781843-10-4非标记 CAS：59468-90-5性状：液体颜色：Colorless to light yellow中文名称：咪达唑仑杂质1-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Solution, -20°C, 2 years纯度 & 产品资料纯度： 99.12%参考文献[1]. Hasegawa T, et, al. Increase in the systemic exposure of primary metabolites of Midazolam in rat arising from CYP inhibition or hepatic dysfunction. Drug Metab Pharmacokinet. 2017 Feb; 32(1): 69-76. [Content Brief][2]. Balk M, et, al. Differential depression of neuronal network activity by midazolam and its main metabolite 1-hydroxymidazolam in cultured neocortical slices. Sci Rep. 2017 Jun 14; 7(1): 3503. [Content Brief][3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-2
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「同位素标记抑制剂」CAS:82005-46-7|Triolein-13C3
作者：德尔塔生物 日期：2025-10-21
生物活性：Triolein-13C3 is the 13C-labeled Triolein. Triolein is a symmetrical triacylglycerol, reduces MMP-1 upregulation, with strong antioxidant and anti-inflammatory properties[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Triolein-13C3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyMMP3 AntibodyMMP12 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)TIMP2 AntibodyMMP9 Antibody (YA285)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)MMP2 AntibodyAsparagine Synthetase AntibodyCalnexin Antibody分子量：888.41Formula：C5413C3H104O6CAS 号：82005-46-7非标记 CAS：122-32-7性状：液体（密度：0.916 g/cm3）颜色：Colorless to light yellow中文名称：三油酸甘油酯 13C3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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「同位素标记抑制剂」CAS:1219402-51-3|Allantoin-13C2,15N4
作者：德尔塔生物 日期：2025-10-21
生物活性：Allantoin-13C2,15N4 is the 13C and 15N labeled Allantoin[1]. Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Allantoin-13C2,15N4 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：164.07Formula：C213C2H615N4O3CAS 号：1219402-51-3非标记 CAS：97-59-6性状：固体颜色：White to off-white中文名称：尿囊素-13C2,15N4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:343338-31-8|trans-Cinnamic acid-d7
作者：德尔塔生物 日期：2025-10-21
生物活性：trans-Cinnamic acid-d7 is the deuterium labeled trans-Cinnamic acid[1]. trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.trans-Cinnamic acid-d7 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：155.20Formula：C9HD7O2CAS 号：343338-31-8非标记 CAS：140-10-3性状：固体颜色：White to off-white中文名称：反式肉桂酸-d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1395950-84-1|Crizotinib-d5
作者：德尔塔生物 日期：2025-10-21
生物活性：Crizotinib-d5 is the deuterium labeled Crizotinib. Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Crizotinib-d5 相关抗体:Met (C-Met) AntibodyPhospho-c-Met (Tyr1349) AntibodyMst2 AntibodyPhospho-Met Antibody (YA175)Caveolin 1 Antibody (YA1782)SESN2 Antibody (YA1934)ALKBH2 Antibody (YA2047)ALKBH4 Antibody (YA2050)ALK-1 Antibody (YA2457)ALKBH1 AntibodyPhospho-GAB1 (Tyr627) AntibodyCaveolin 2 Antibody (YA2387)SESN1 Antibody (YA2739)Caveolin 3 Antibody (YA2869)分子量：455.37Formula：C21H17D5Cl2FN5OCAS 号：1395950-84-1非标记 CAS：877399-52-5性状：固体颜色：White to yellow中文名称：克唑替尼 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1173018-24-0|Sodium 3-methyl-2-oxobutanoate-13C5
作者：德尔塔生物 日期：2025-10-21
生物活性：Sodium 3-methyl-2-oxobutanoate-13C5 is the 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Sodium 3-methyl-2-oxobutanoate-13C5 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：143.06Formula：13C5H7NaO3CAS 号：1173018-24-0非标记 CAS：3715-29-5性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1173021-86-7|2-Ketoglutaric acid-d6
作者：德尔塔生物 日期：2025-10-21
生物活性：2-Ketoglutaric acid-d6 is the deuterium labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.2-Ketoglutaric acid-d6 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyMiTF AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)ZAP70 Antibody (YP4051)Asparagine Synthetase AntibodyCalnexin AntibodyCD3 epsilon AntibodyCD3D AntibodyKi67 Antibody (YA001)分子量：152.14Formula：C5D6O5CAS 号：1173021-86-7性状：固体颜色：White to off-white中文名称：α-酮戊二酸-d6运输条件：Room temperature in continental US; may vary elsewhere.储
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「同位素标记抑制剂」CAS:74495-69-5|Guaiacol-d3
作者：德尔塔生物 日期：2025-10-21
生物活性：Guaiacol-d3 is the deuterium labeled Guaiacol. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Guaiacol has an anti-inflammatory activity[1].分子量：127.16Formula：C7H5D3O2CAS 号：74495-69-5非标记 CAS：90-05-1性状：液体（密度：1.137 g/cm3）颜色：Light yellow to light brown中文名称：愈创木酚-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Pure form-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:185056-83-1|Coumarin-d4
作者：德尔塔生物 日期：2025-10-21
生物活性：Coumarin-d4 is the deuterium labeled Coumarin. Coumarin is the primary bioactive ingredient in Radix Glehniae, named Beishashen in China, which possesses many pharmacological activities, including anticancer, anti-inflammation and antivirus activities.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Coumarin-d4 相关抗体:Poliovirus Receptor Antibody (YA2556)分子量：150.17Formula：C9H2D4O2CAS 号：185056-83-1非标记 CAS：91-64-5性状：固体颜色：White to off-white中文名称：香豆素 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1092942-82-9|Imatinib-d8
作者：德尔塔生物 日期：2025-10-21
生物活性：Imatinib-d8 is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2].分子量：501.65Formula：C29H23D8N7OCAS 号：1092942-82-9非标记 CAS：152459-95-5性状：固体颜色：White to light yellow中文名称：伊马替尼 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」Nisoldipine-d7
作者：德尔塔生物 日期：2025-10-21
生物活性：Nisoldipine-d7 (BAY-k 5552-d7) is the deuterium labeled Nisoldipine. Nisoldipine(BAY-k 5552) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nisoldipine-d7 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCatalase Antibody (YA552)Catalase Antibody (YA811)Cardiac Troponin I/TNNC1 AntibodyC Reactive Protein Antibody (YA941)SCGN Antibody (YA1167)PARK7/DJ1 Antibody (YA1799)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)CRCP Antibody (YA3350)C Reactive Protein Antibody (YA939)C Reactive Protein Antibody (YA940)Annexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)PON1 Antibody (YA1666)PON2 Antibody (YA1688)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)分子量：395.46Formula：C20H17D7N2O6CAS 号：1189718-34-0非标记 CAS：63675-72-9中文名称：尼索地平 d7运输条件：Room t
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「同位素标记抑制剂」Nisoldipine-d4
作者：德尔塔生物 日期：2025-10-21
生物活性：Nisoldipine-d4 (BAY-k 5552-d4) is the deuterium labeled Nisoldipine. Nisoldipine(BAY-k 5552) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nisoldipine-d4 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCatalase Antibody (YA552)Catalase Antibody (YA811)Cardiac Troponin I/TNNC1 AntibodyC Reactive Protein Antibody (YA941)SCGN Antibody (YA1167)PARK7/DJ1 Antibody (YA1799)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)CRCP Antibody (YA3350)C Reactive Protein Antibody (YA939)C Reactive Protein Antibody (YA940)Annexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)PON1 Antibody (YA1666)PON2 Antibody (YA1688)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)分子量：392.44Formula：C20H20D4N2O6CAS 号：1219795-47-7非标记 CAS：63675-72-9中文名称：尼索地平 d4运输条件：Room t
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「同位素标记抑制剂」Loxapine-d8 hydrochloride
作者：德尔塔生物 日期：2025-10-21
生物活性：Loxapine-d8 (hydrochloride) is the deuterium labeled Loxapine. Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Loxapine-d8 hydrochloride 相关抗体:MTNR1A Antibody分子量：335.86Formula：C18H11D8Cl2N3OCAS 号：1246820-19-8非标记 CAS：54810-23-0中文名称：盐酸洛沙平-d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (537 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Singh AN, et al. A neurochemical basis for the antipsychotic activity of loxapine: interactions with dopamine D1, D2, D4 and serotonin 5-HT2 receptor subtypes. J Psychiatry Neurosci. 1996 Jan;21(1):29-35. [Content Brief][3]. Labuzek K, et al. Chlorpromazine and loxapine reduce interleukin-1beta and interleukin-2 release by rat mixed glial and microglial cell cultures. Eur Neuropsychopharmacol. 2005 Jan;15(1):23-30. [Content B
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「同位素标记抑制剂」Dexpramipexole-d3 dihydrochloride
作者：德尔塔生物 日期：2025-10-21
生物活性：Dexpramipexole-d3 (dihydrochloride) is the deuterium labeled Dexpramipexole. Dexpramipexole((R)-Pramipexole), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist[1][2].IC50 & Target：D3 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Dexpramipexole-d3 dihydrochloride 相关抗体:DRD2 AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：287.27Formula：C10H16D3Cl2N3SCAS 号：1432230-09-5非标记 CAS：104632-27-1中文名称：普拉克索杂质E-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Rudnicki SA, Berry JD, Ingersoll E, et al. Dexpramipexole effects on functional decline and survival in subjects with amyotrophic lateral sclerosis in a Phase II study: subgroup analysis of dem
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「同位素标记抑制剂」Olmesartan medoxomil-d6
作者：德尔塔生物 日期：2025-10-21
生物活性：Olmesartan medoxomil-d6 (CS 866-d6) is the deuterium labeled Olmesartan medoxomil. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM[1][2].IC50 & Target：AT1 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Olmesartan medoxomil-d6 相关抗体:Natriuretic Peptides A Antibody (YA1381)Angiotensinogen Antibody (YA2097)Natriuretic Peptides B Antibody (YA999)Natriuretic Peptides B Antibody (YA1000)Natriuretic Peptides B Antibody (YA1001)AGTR2 Antibody (YA3090)Angiotensin II Type 1 Receptor Antibody (YA3358)分子量：564.62Formula：C29H24D6N6O6CAS 号：1127298-67-2非标记 CAS：144689-63-4中文名称：奥美沙坦酯 d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (536 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Senda A, et al. Effects of Angiotensin II Receptor Blockers on Metabolism of Arachidonic Acid via CYP2C8. Biol Pharm Bull. 2015;38(12):1975-9. [Content Brief][3]. S
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