-
Lawsone-d4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Lawsone-d4 is the deuterium labeled Lawsone. Lawsone is a naphthoquinone dye isolated from leaves of Lawsonia inermis that shows antimicrobial and antioxidant activity[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Lawsone-d4 相关抗体:SDHA Antibody分子量：178.18Formula：C10H2D4O3非标记 CAS：83-72-7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Tripathi RD, et al. A fungitoxic principle from the leaves of lawsonia inermis lam. Experientia. 1978 Jan 15;34(1):51-2. [Content Brief]
-
Kukoamine A-d8 dihydrochloride，地骨皮甲素-d8「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Kukoamine A-d8 (dihydrochloride) is deuterium labeled Kukoamine A. Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity[1].IC50 & Target：Trypanosoma体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：611.63Formula：C28H36D8Cl2N4O6非标记 CAS：75288-96-9中文名称：地骨皮甲素-d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Ponasik JA, et al. Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase. Biochem J. 1995 Oct 15;311 ( Pt 2):371-5. [Content Brief]
-
D-(+-Cellobiose-13C「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：D-(+)-Cellobiose-13C is the 13C labeled D-(+)-Cellobiose. D-(+)-Cellobiose is an endogenous metabolite[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.D-(+)-Cellobiose-13C 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：343.29Formula：C1113CH22O11非标记 CAS：528-50-7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (523 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2
-
4-Hydroxyphenylacetic acid-d4，4-羟基苯乙酸-d4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：4-Hydroxyphenylacetic acid-d4 is the deuterium labeled 4-Hydroxyphenylacetic acid[1]. 4-hydroxyphenylacetic acid, a major microbiota-derived metabolite of polyphenols, is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.4-Hydroxyphenylacetic acid-d4 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)PGK1 AntibodyGAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyKeap1 AntibodyPhospho-Nrf2 (Ser40) Antibody (YA169)TSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyPhospho-Nrf2 (Ser40) Antibody (YA168)Heme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)分子量：156.17Formula：C8H4D4O3非标记 CAS：156-38-7中文名称：4-羟基苯乙酸-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of
-
Linoleic Acid-d11 methyl ester，亚油酸甲酯甲酯 d11「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Linoleic Acid-d11 methyl ester is the deuterium labeled Linoleic Acid methyl ester[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：305.54Formula：C19H23D11O2非标记 CAS：112-63-0中文名称：亚油酸甲酯甲酯 d11运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (513 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
-
Salvigenin-d9，Psathyrotin-d9「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Salvigenin-d9 is the deuterium labeled Salvigenin. Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Salvigenin-d9 相关抗体:FOXO1A AntibodyBeclin 1 AntibodyAtg12 AntibodyATG5 AntibodyBmi1 AntibodyFOXO4 AntibodyFOXP3 AntibodyGABARAP AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyPhospho-FOXO3a(Ser253) AntibodyAPG5L AntibodyATG10 Antibody (YA603)ATG3 AntibodyATG4A AntibodyATG4C AntibodyATG7 AntibodyFOXO1 Antibody (YA430)FOXO3 AntibodyFOXP3 Antibody (YA759)FTO AntibodyPhospho-FOXO3A (Ser253) AntibodyFOXO1 AntibodyATG10 AntibodyGranulin Antibody (YA1162)ATG13 Antibody (YA1650)ATG9A Antibody (YA3081)LAMP2 Antibody (YA310)WIPI1 Antibody (YA1721)ATG16L1 Antibody (YA2187)分子量：337.37Formula：C18H7D9O6非标记 CAS：19103-54-9中文名称：三裂鼠尾草素 d9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmac
-
L-Histidine-13C6,15N3 hydrochloride，L-组氨酸盐酸盐 -13C6,15N3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：L-Histidine-13C6,15N3 hydrochloride is the 13C and 15N labled L-Histidine (HY-N0832). L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[2]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：200.55Formula：13C6H10Cl15N3O2非标记 CAS：71-00-1中文名称：L-组氨酸盐酸盐 -13C6,15N3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Bou Zeidan M, et al. L-histidine inhibits biofilm formation and FLO11-associated phenotypes in Saccharomyces cerevisiae flor yeasts. PLoS One. 2014 Nov 4;9(11):e112141. [Content Brief][2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
-
Glucosamine-13C6,15N hydrochloride，盐酸氨基葡萄糖-13C6,15N; D-(+-Glucosamine-13C6,15N hydrochloride; Chitosamine-13C6,15N hydrochloride「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Glucosamine-13C6,15N (hydrochloride) is the 13C and 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids,体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Glucosamine-13C6,15N hydrochloride 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyHIF1 alpha AntibodyMETTL3 AntibodyHIF1 beta AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Catalase Antibody (YA552)Catalase Antibody (YA811)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)分子量：222.58Formula：13C6H14Cl15NO5非标记 CAS：66-84-2中文名称：盐酸氨基葡萄糖-13C6,15N； 氨基葡萄糖盐酸盐-13C6,15N； D-氨基葡萄糖盐酸盐-13C6,15N运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product un
-
Hydroxytyrosol-d5，羟基酪醇-d5; DOPET-d5; 3,4-Dihydroxyphenethyl alcohol-d5; 3-Hydroxytyrosol-d5「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Hydroxytyrosol-d5 is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Hydroxytyrosol-d5 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySDHA AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 Antibody分子量：159.19Formula：C8H5D5O3非标记 CAS：10597-60-1中文名称：羟基酪醇-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530
-
Xylitol-d7，Xylite-d7「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Xylitol-d7 is the deuterium labeled Xylit[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Xylitol-d7 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：159.19Formula：C5H5D7O5非标记 CAS：87-99-0中文名称：木糖醇 d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. http://en.wikipedia.org
-
Benperidol-d4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Benperidol-d4 is deuterium labeled Benperidol.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：385.47Formula：C22H20D4FN3O2非标记 CAS：2062-84-2运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
-
Doxorubicinol-13C,d3 TFA，Adriamycinol-13C,d3 TFA; DXR-OL-13C,d3 TFA「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Doxorubicinol-13C,d3 (TFA) is the deuterium and 13C labeled Doxorubicinol TFA[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Doxorubicinol-13C,d3 TFA 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：663.57Formula：C2813CH29D3F3NO13非标记 CAS：54193-28-1运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (518 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Co
-
Fluorofenidone-d3，AKF-PD-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Fluorofenidone-d3 is deuterium labeled Fluorofenidone. Fluorofenidone (AKF-PD), an analogue of AMR69, shows equivalent antifibrotic activity, lower toxicity and longer half-life. Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fluorofenidone-d3 相关抗体:Phospho-AKT1 (Ser473) AntibodyAKT1/2/3 Antibody (YA633)Phospho-AKT (Thr308) AntibodyPhospho-AKT1(Ser473) AntibodyPI3 Kinase p110 gamma Antibody (YA690)AKT1 Antibody (YA834)AKT1 Antibody (YA634)CD41 AntibodyCD19 Antibody (YA543)Hamartin AntibodyPI 3 Kinase p85 alpha AntibodyAKT1/AKT2/AKT3 Antibody (YA635)CD19 Antibody (YA807)Lyn Antibody (YA707)Phospho-PI3 Kinase p85/p55 (Tyr467/Tyr199) AntibodyPI3 Kinase p55 gamma AntibodyPI3 Kinase p85 alpha Antibody (YA689)PI3 Kinase p85 beta Antibody (YA688)PI3 Kinase p110 alpha/PIK3CA Antibody (YA3537)phospho-PI3 Kinase p110 beta (Ser1070) AntibodyTRIB3 Antibody (YA2174)PIK3C3 Antibody (YA2789)PI 3 Kinase p150 Antibody (YA2823)PDPK1 Antibody (YA1569)PI3 Kinase p110 delta Antibody (YA1617)AS160 Antibody (YA2170)
-
Amethopterin-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Amethopterin-d3 is deuterium labeled Amethopterin.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：457.46Formula：C20H19D3N8O5非标记 CAS：60388-53-6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (515 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
-
Umeclidinium-d10 bromide，GSK573719A-d10「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-05-29
生物活性：Umeclidinium-d10 (bromide) is the deuterium labeled Umeclidinium bromide. Umeclidinium bromide is a novel mAChR antagonist. The affinity (Ki) of Umeclidinium bromide for the cloned human M1-M5 mAChRs ranges from 0.05 to 0.16 nM.IC50 & Target：mAChR1mAChR5体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Umeclidinium-d10 bromide 相关抗体:Muscarinic Acetylcholine receptor M3 AntibodyMuscarinic Acetylcholine Receptor M2 Antibody (YA2610)分子量：518.55Formula：C29H24D10BrNO2非标记 CAS：869113-09-7中文名称：芜地溴铵 d10 (溴盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Salmon M, et al. Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases. J Pharmacol Exp Ther. 2013 May;345(2):260-70. [Content Brief][3]. Cazzola M, et al. Pharmacology and ther
咨询热线
18133906270
德尔塔官方微信