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CAS:352438-69-8|2,4-D-d5

CAS:352438-69-8|2,4-D-d5

作者:德尔塔生物 日期:2025-07-08

生物活性:2,4-D-d5 is the deuterium labeled 2,4-D[1]. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.2,4-D-d5 相关抗体:Ctip2 AntibodyRb AntibodyPhospho-Rb (Ser807) AntibodyRPA32 Antibody (YA679)CDT1 AntibodyDNA-PKcs/PRKDC AntibodyHes1 AntibodyJunB AntibodyLIN28A AntibodyLin28B AntibodyMCM2 AntibodyNanog AntibodyNucleolin AntibodyPCNA AntibodyPDX1 AntibodyRbBP5 AntibodyS100A4 AntibodySP1 AntibodyBRCA1 Antibody (YA819)Argonaute 2 AntibodyBRCA1 AntibodyElongation Factor 1A1 AntibodyKAP1 AntibodyMCM2 Antibody (YA705)MLH1 Antibody (YA703)RNA Polymerase II Subunit B1 AntibodyRPA70 Antibody (YA678)SP7/Osterix AntibodyDNA PKcs Antibody (YA957)DNA PKcs Antibody (YA959)分子量:226.07Formula:C8HD5Cl2O3CAS 号:352438-69-8非标记 CAS:94-75-7性状:固体颜色:White to light yellow运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, protect from light, stored under nitrogen*In solvent : -80°C, 6

CAS:1219806-41-3|4-Methylbenzylidene camphor-d4,4-甲基苄亚基樟脑-d4;恩扎卡门-d4;恩扎樟烯-d4

CAS:1219806-41-3|4-Methylbenzylidene camphor-d4,4-甲基苄亚基樟脑-d4;恩扎卡门-d4;恩扎樟烯-d4

作者:德尔塔生物 日期:2025-07-08

生物活性:4-Methylbenzylidene camphor-d4 is the deuterium labeled 4-Methylbenzylidene camphor[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.4-Methylbenzylidene camphor-d4 相关抗体:CHRNA9 AntibodyChAT Antibody分子量:258.39Formula:C18H18D4OCAS 号:1219806-41-3非标记 CAS:36861-47-9性状:固体颜色:White to off-white中文名称:4-甲基苄亚基樟脑-d4;恩扎卡门-d4;恩扎樟烯-d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:1093659-90-5|Ezetimibe-d4,依折麦布-D4; SCH 58235-d4

CAS:1093659-90-5|Ezetimibe-d4,依折麦布-D4; SCH 58235-d4

作者:德尔塔生物 日期:2025-07-08

生物活性:Ezetimibe-d4 is the deuterium labeled Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.分子量:413.45Formula:C24H17D4F2NO3CAS 号:1093659-90-5非标记 CAS:163222-33-1性状:固体颜色:White to off-white中文名称:依泽替米贝 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:1246814-53-8|Nepafenac-d5,奈帕芬胺 D5; AHR-9434-d5; AL-6515-d5

CAS:1246814-53-8|Nepafenac-d5,奈帕芬胺 D5; AHR-9434-d5; AL-6515-d5

作者:德尔塔生物 日期:2025-07-08

生物活性:Nepafenac-d5 is the deuterium labeled Nepafenac, which is a selective COX-2 inhibitor.分子量:259.31Formula:C15H9D5N2O2CAS 号:1246814-53-8非标记 CAS:78281-72-8性状:固体颜色:Light yellow to yellow中文名称:奈帕芬胺 d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:2 years-20°C:1 year

CAS:774596-22-4|Cetirizine-d8,左西替利嗪-d8

CAS:774596-22-4|Cetirizine-d8,左西替利嗪-d8

作者:德尔塔生物 日期:2025-07-08

生物活性:Cetirizine-d8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].IC50 & Target:H1 Receptor分子量:396.94Formula:C21H17D8ClN2O3CAS 号:774596-22-4非标记 CAS:83881-51-0性状:固体颜色:Off-white to light yellow中文名称:左西替利嗪-d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:1638885-65-0|Apalutamide-d4,ARN-509-d4

CAS:1638885-65-0|Apalutamide-d4,ARN-509-d4

作者:德尔塔生物 日期:2025-07-08

生物活性:Apalutamide-d4 is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].分子量:481.46Formula:C21H11D4F4N5O2SCAS 号:1638885-65-0非标记 CAS:956104-40-8性状:固体颜色:White to light yellow中文名称:阿帕鲁胺 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:2254100-49-5|Osimertinib-13C,d3,AZD-9291-13C,d3; Mereletinib-13C,d3

CAS:2254100-49-5|Osimertinib-13C,d3,AZD-9291-13C,d3; Mereletinib-13C,d3

作者:德尔塔生物 日期:2025-07-08

生物活性:Osimertinib-13C,d3 is the deuterium and 13C labeled Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Osimertinib-13C,d3 相关抗体:c-Fos AntibodyCaveolin-1 AntibodyPhospho-EGFR (Tyr1068) AntibodyPhospho-EGFR (Tyr1173) Antibodyc-Fos Antibody (YA506)EGF AntibodyEGFR AntibodyEGR1 AntibodyPhospholipase C gamma 1 AntibodyPhospho-EGFR (Tyr1068) Antibody (YA204)HER2 AntibodyEGFR Antibody (YA775)HER2 Antibody (YA771)ErbB 4 AntibodyPhospho-EGFR (Tyr1092) AntibodyTGF alpha AntibodyHBEGF Antibody (YA1801)ErbB 3 AntibodyGRB7 Antibody (YA1165)分子量:503.62Formula:C2713CH30D3N7O2CAS 号:2254100-49-5非标记 CAS:1421373-65-0性状:固体颜色:White to off-white中文名称:奥斯替尼 13C,d3;奥希替尼 13C,d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, protect from light, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)纯度 & 产品资料纯度: 99.14%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokin

CAS:1134803-16-9|Imatinib-d4,STI571 d4; CGP-57148B d4

CAS:1134803-16-9|Imatinib-d4,STI571 d4; CGP-57148B d4

作者:德尔塔生物 日期:2025-07-08

生物活性:Imatinib-d4 is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2].分子量:497.63Formula:C29H27D4N7OCAS 号:1134803-16-9非标记 CAS:152459-95-5性状:固体颜色:Off-white to light yellow中文名称:伊马替尼 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:1383572-19-7|Cabazitaxel-d9,XRP6258-d9; RPR-116258A-d9; taxoid XRP6258-d9

CAS:1383572-19-7|Cabazitaxel-d9,XRP6258-d9; RPR-116258A-d9; taxoid XRP6258-d9

作者:德尔塔生物 日期:2025-07-08

生物活性:Cabazitaxel-d9 is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cabazitaxel-d9 相关抗体:alpha Tubulin AntibodyLC3A/B AntibodyBeta Tubulin Antibodybeta Tubulin Antibody (YA839)Doublecortin AntibodyLC3B Antibody (YA308)Stathmin 1 Antibody (YA049)Stathmin 1 Antibody (YA050)alpha Tubulin (acetyl K40) Antibodybeta III Tubulin Antibodygamma Tubulin AntibodyLC3B AntibodyBeta Tubulin Antibody (HRP) (YA865)Cytokeratin 5 AntibodyMAP2 AntibodyDM1 Antibody (YA898)CK18 AntibodyCytokeratin 19 AntibodyCytokeratin 7 Antibody (YA951)Cytokeratin 15 Antibody (YA1493)p63 Antibody (YA1531)Cytokeratin 6 Antibody (YA1701)Cytokeratin 4 Antibody (YA1762)Cytokeratin 10 Antibody (YA1857)Cytokeratin 14 Antibody (YA1876)Cytokeratin 1 Antibody (YA2665)Stanniocalcin 1 Antibody (YA2690)Cytokeratin 13 Antibody (YA2695)HRH3 Antibody (YA2701)Phospho-alpha Tubulin (Tyr272) Antibody (YA3041)分子量:844.99Formula:C45H48D9NO14CAS 号:1383572-19-7非标记 CAS:183133-96-2性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式

CAS:1884269-07-1|Sacubitril-d4,AHU-377-d4

CAS:1884269-07-1|Sacubitril-d4,AHU-377-d4

作者:德尔塔生物 日期:2025-07-08

生物活性:Sacubitril-d4 is the deuterium labeled Sacubitril. Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril (AHU-377) is a component of the heart failure medicine LCZ696.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:415.52Formula:C24H25D4NO5CAS 号:1884269-07-1非标记 CAS:149709-62-6性状:固体颜色:White to off-white中文名称:沙库必曲 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

CAS:1262670-81-4|Xanthine-13C,15N2,黄嘌呤-13C,15N2

CAS:1262670-81-4|Xanthine-13C,15N2,黄嘌呤-13C,15N2

作者:德尔塔生物 日期:2025-07-08

生物活性:Xanthine-13C,15N2 is a 15N-labeled and 13C-labled Xanthine (HY-W017389). Xanthine is a plant alkaloid with mild stimulant activity of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:155.09Formula:C413CH4N215N2O2CAS 号:1262670-81-4非标记 CAS:69-89-6性状:固体颜色:White to light yellow中文名称:黄嘌呤-13C,15N2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:2143107-56-4|Olaparib-d5,AZD2281-d5; KU0059436-d5

CAS:2143107-56-4|Olaparib-d5,AZD2281-d5; KU0059436-d5

作者:德尔塔生物 日期:2025-07-08

生物活性:Olaparib-d5 (AZD2281-d5) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[1][2][3][4].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Olaparib-d5 相关抗体:PARP1 AntibodyPARP2 AntibodyCleaved PARP AntibodyCleaved-PARP1 AntibodyPARP1 Antibody (YA245)StAR AntibodySSB Antibody (YA668)GTF2H1 Antibody (YA1067)BRAT1 Antibody (YA2294)BRCC36 Antibody (YA2298)Killin Antibody (YA3144)分子量:439.49Formula:C24H18D5FN4O3CAS 号:2143107-56-4非标记 CAS:763113-22-0性状:固体颜色:White to off-white中文名称:奥拉帕尼 d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

CAS:1433-11-0|Urea-d4,1,1,3,3-Tetradeuteriourea

CAS:1433-11-0|Urea-d4,1,1,3,3-Tetradeuteriourea

作者:德尔塔生物 日期:2025-07-08

生物活性:Urea-d4 is the deuterium labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[2]. A potent emollient and keratolytic agent[3]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[4]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Urea-d4 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:64.08Formula:CD4N2OCAS 号:1433-11-0性状:固体颜色:White to off-white中文名称:尿素-d4运输条件:Room temperature in continental US; may vary el

CAS:1219794-54-3|N-Nitrosodiethylamine-d10,Diethylnitrosamine-d10;  DEN-d10

CAS:1219794-54-3|N-Nitrosodiethylamine-d10,Diethylnitrosamine-d10; DEN-d10

作者:德尔塔生物 日期:2025-07-08

生物活性:N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.N-Nitrosodiethylamine-d10 相关抗体:Ctip2 AntibodyRb AntibodyPhospho-Rb (Ser807) AntibodyRPA32 Antibody (YA679)CDT1 AntibodyDNA-PKcs/PRKDC AntibodyHes1 AntibodyJunB AntibodyLIN28A AntibodyLin28B AntibodyMCM2 AntibodyNanog AntibodyNucleolin AntibodyPCNA AntibodyPDX1 AntibodyRbBP5 AntibodyS100A4 AntibodySP1 AntibodyBRCA1 Antibody (YA819)Argonaute 2 AntibodyBRCA1 AntibodyElongation Factor 1A1 AntibodyKAP1 AntibodyMCM2 Antibody (YA705)MLH1 Antibody (YA703)RNA Polymerase II Subunit B1 AntibodyRPA70 Antibody (YA678)SP7/Osterix AntibodyDNA PKcs Antibody (YA957)DNA PKcs Antibody (YA959)分子量:112.2

CAS:1192260-78-8|Naringenin-d4,柚皮素-d4

CAS:1192260-78-8|Naringenin-d4,柚皮素-d4

作者:德尔塔生物 日期:2025-07-08

生物活性:Naringenin-d4 is the deuterated version of Naringenin (HY-N0100). Naringenin shows strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity[1].分子量:276.28Formula:C15H8D4O5CAS 号:1192260-78-8非标记 CAS:480-41-1性状:固体颜色:White to off-white中文名称:柚皮素-d4; 柑桔素-d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month