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CAS:1189943-37-0|Prochlorperazine Sulfoxide-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：Prochlorperazine Sulfoxide-d3 is a deuterium labeled Prochlorperazine Sulfoxide. Prochlorperazine Sulfoxide is the major metabolite of the antiemetic Prochlorperazine[1][2].分子量：392.96Formula：C20H21D3ClN3OSCAS 号：1189943-37-0非标记 CAS：10078-27-0性状：固体颜色：White to light yellow运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1189881-87-5|Bisoprolol-d5，比索洛尔-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Bisoprolol-d5 is the deuterium labeled Bisoprolol. Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker. Bisoprolol has little activity on β2-receptor and has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Bisoprolol-d5 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：330.47Formula：C18H26D5NO4CAS 号：1189881-87-5非标记 CAS：104344-23-2中文名称：比索洛尔-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Jillian G Baker, et al. The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. Br J Pharmacol. 2005 Feb;144(3):317-22. [Content Brief][3]. Maria Hoeltzenbein, et al. Pregnancy outcome after first trimes
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CAS:1246817-86-6|Cyclazodone-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Cyclazodone-d5 is the deuterium labeled Cyclazodone[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：221.27Formula：C12H7D5N2O2CAS 号：1246817-86-6非标记 CAS：14461-91-7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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CAS:1215383-78-0|Dehydro Aripiprazole-d8 hydrochloride
作者：德尔塔生物 日期：2025-07-08
生物活性：Dehydro Aripiprazole-d8 (hydrochloride) is the deuterium labeled Dehydro Aripiprazole hydrochloride[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：490.88Formula：C23H18D8Cl3N3O2CAS 号：1215383-78-0非标记 CAS：1008531-60-9性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, protect from light, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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CAS:1020719-76-9|Risperidone-d4，利培酮D4; R 64 766-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Risperidone-d4 is the deuterium labeled Risperidone. Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.IC50 & Target：D2 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Risperidone-d4 相关抗体:P Glycoprotein AntibodyDRD2 AntibodyMTNR1A AntibodyMRP1 Antibody (YA1583)Dopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)MRP4 Antibody (YA1166)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：414.51Formula：C23H23D4FN4O2CAS 号：1020719-76-9非标记 CAS：106266-06-2性状：固体颜色：White to off-white中文名称：利培酮-d4 杂质33运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:352438-69-8|2,4-D-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：2,4-D-d5 is the deuterium labeled 2,4-D[1]. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.2,4-D-d5 相关抗体:Ctip2 AntibodyRb AntibodyPhospho-Rb (Ser807) AntibodyRPA32 Antibody (YA679)CDT1 AntibodyDNA-PKcs/PRKDC AntibodyHes1 AntibodyJunB AntibodyLIN28A AntibodyLin28B AntibodyMCM2 AntibodyNanog AntibodyNucleolin AntibodyPCNA AntibodyPDX1 AntibodyRbBP5 AntibodyS100A4 AntibodySP1 AntibodyBRCA1 Antibody (YA819)Argonaute 2 AntibodyBRCA1 AntibodyElongation Factor 1A1 AntibodyKAP1 AntibodyMCM2 Antibody (YA705)MLH1 Antibody (YA703)RNA Polymerase II Subunit B1 AntibodyRPA70 Antibody (YA678)SP7/Osterix AntibodyDNA PKcs Antibody (YA957)DNA PKcs Antibody (YA959)分子量：226.07Formula：C8HD5Cl2O3CAS 号：352438-69-8非标记 CAS：94-75-7性状：固体颜色：White to light yellow运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, protect from light, stored under nitrogen*In solvent : -80°C, 6
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CAS:1219806-41-3|4-Methylbenzylidene camphor-d4，4-甲基苄亚基樟脑-d4；恩扎卡门-d4；恩扎樟烯-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：4-Methylbenzylidene camphor-d4 is the deuterium labeled 4-Methylbenzylidene camphor[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.4-Methylbenzylidene camphor-d4 相关抗体:CHRNA9 AntibodyChAT Antibody分子量：258.39Formula：C18H18D4OCAS 号：1219806-41-3非标记 CAS：36861-47-9性状：固体颜色：White to off-white中文名称：4-甲基苄亚基樟脑-d4；恩扎卡门-d4；恩扎樟烯-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1093659-90-5|Ezetimibe-d4，依折麦布-D4; SCH 58235-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Ezetimibe-d4 is the deuterium labeled Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.分子量：413.45Formula：C24H17D4F2NO3CAS 号：1093659-90-5非标记 CAS：163222-33-1性状：固体颜色：White to off-white中文名称：依泽替米贝 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1246814-53-8|Nepafenac-d5，奈帕芬胺 D5; AHR-9434-d5; AL-6515-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Nepafenac-d5 is the deuterium labeled Nepafenac, which is a selective COX-2 inhibitor.分子量：259.31Formula：C15H9D5N2O2CAS 号：1246814-53-8非标记 CAS：78281-72-8性状：固体颜色：Light yellow to yellow中文名称：奈帕芬胺 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：2 years-20°C：1 year
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CAS:774596-22-4|Cetirizine-d8，左西替利嗪-d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Cetirizine-d8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].IC50 & Target：H1 Receptor分子量：396.94Formula：C21H17D8ClN2O3CAS 号：774596-22-4非标记 CAS：83881-51-0性状：固体颜色：Off-white to light yellow中文名称：左西替利嗪-d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1638885-65-0|Apalutamide-d4，ARN-509-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Apalutamide-d4 is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].分子量：481.46Formula：C21H11D4F4N5O2SCAS 号：1638885-65-0非标记 CAS：956104-40-8性状：固体颜色：White to light yellow中文名称：阿帕鲁胺 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:2254100-49-5|Osimertinib-13C,d3，AZD-9291-13C,d3; Mereletinib-13C,d3
作者：德尔塔生物 日期：2025-07-08
生物活性：Osimertinib-13C,d3 is the deuterium and 13C labeled Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Osimertinib-13C,d3 相关抗体:c-Fos AntibodyCaveolin-1 AntibodyPhospho-EGFR (Tyr1068) AntibodyPhospho-EGFR (Tyr1173) Antibodyc-Fos Antibody (YA506)EGF AntibodyEGFR AntibodyEGR1 AntibodyPhospholipase C gamma 1 AntibodyPhospho-EGFR (Tyr1068) Antibody (YA204)HER2 AntibodyEGFR Antibody (YA775)HER2 Antibody (YA771)ErbB 4 AntibodyPhospho-EGFR (Tyr1092) AntibodyTGF alpha AntibodyHBEGF Antibody (YA1801)ErbB 3 AntibodyGRB7 Antibody (YA1165)分子量：503.62Formula：C2713CH30D3N7O2CAS 号：2254100-49-5非标记 CAS：1421373-65-0性状：固体颜色：White to off-white中文名称：奥斯替尼 13C,d3；奥希替尼 13C,d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, protect from light, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)纯度 & 产品资料纯度： 99.14%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokin
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CAS:1134803-16-9|Imatinib-d4，STI571 d4; CGP-57148B d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Imatinib-d4 is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2].分子量：497.63Formula：C29H27D4N7OCAS 号：1134803-16-9非标记 CAS：152459-95-5性状：固体颜色：Off-white to light yellow中文名称：伊马替尼 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1383572-19-7|Cabazitaxel-d9，XRP6258-d9; RPR-116258A-d9; taxoid XRP6258-d9
作者：德尔塔生物 日期：2025-07-08
生物活性：Cabazitaxel-d9 is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cabazitaxel-d9 相关抗体:alpha Tubulin AntibodyLC3A/B AntibodyBeta Tubulin Antibodybeta Tubulin Antibody (YA839)Doublecortin AntibodyLC3B Antibody (YA308)Stathmin 1 Antibody (YA049)Stathmin 1 Antibody (YA050)alpha Tubulin (acetyl K40) Antibodybeta III Tubulin Antibodygamma Tubulin AntibodyLC3B AntibodyBeta Tubulin Antibody (HRP) (YA865)Cytokeratin 5 AntibodyMAP2 AntibodyDM1 Antibody (YA898)CK18 AntibodyCytokeratin 19 AntibodyCytokeratin 7 Antibody (YA951)Cytokeratin 15 Antibody (YA1493)p63 Antibody (YA1531)Cytokeratin 6 Antibody (YA1701)Cytokeratin 4 Antibody (YA1762)Cytokeratin 10 Antibody (YA1857)Cytokeratin 14 Antibody (YA1876)Cytokeratin 1 Antibody (YA2665)Stanniocalcin 1 Antibody (YA2690)Cytokeratin 13 Antibody (YA2695)HRH3 Antibody (YA2701)Phospho-alpha Tubulin (Tyr272) Antibody (YA3041)分子量：844.99Formula：C45H48D9NO14CAS 号：1383572-19-7非标记 CAS：183133-96-2性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式
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CAS:1884269-07-1|Sacubitril-d4，AHU-377-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Sacubitril-d4 is the deuterium labeled Sacubitril. Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril (AHU-377) is a component of the heart failure medicine LCZ696.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：415.52Formula：C24H25D4NO5CAS 号：1884269-07-1非标记 CAS：149709-62-6性状：固体颜色：White to off-white中文名称：沙库必曲 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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