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CAS:1216653-51-8|Miconazole-d5 nitrate，咪康唑硝酸盐-d5; R18134-d5 nitrate
作者：德尔塔生物 日期：2025-06-04
生物活性：Miconazole-d5 (nitrate) is the deuterium labeled Miconazole. Miconazole (R18134) is an imidazole antifungal agent. Miconazole also has antibacterial effects[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Miconazole-d5 nitrate 相关抗体:SDHA AntibodyMRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：484.17Formula：C18H10D5Cl4N3O4CAS 号：1216653-51-8非标记 CAS：22916-47-8中文名称：咪康唑硝酸盐-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2].
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CAS:1329838-45-0|Phenoxybenzamine-d5 hydrochloride，盐酸酚苄明 d5 (盐酸盐
作者：德尔塔生物 日期：2025-06-04
生物活性：Phenoxybenzamine-d5 (hydrochloride) is the deuterium labeled Phenoxybenzamine hydrochloride. Phenoxybenzamine hydrochloride is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine hydrochloride also shows antitumor activity[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Phenoxybenzamine-d5 hydrochloride 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：345.32Formula：C18H18D5Cl2NOCAS 号：1329838-45-0非标记 CAS：63-92-3中文名称：盐酸酚苄明 d5 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Habbe N, et al. Urapidil in the preoperative treatment of pheochromocytomas: a safe and cost-effective method. World J Surg. 2013 May;37(5):1141-6. [C
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CAS:67151-02-4|Clonidine-d4 hydrochloride，可乐定 d4 (盐酸盐
作者：德尔塔生物 日期：2025-06-04
生物活性：Clonidine-d4 (hydrochloride) is the deuterium labeled Clonidine. Clonidine hydrochloride is an alpha 2-adrenergic agonist[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Clonidine-d4 hydrochloride 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：270.58Formula：C9H6D4Cl3N3CAS 号：67151-02-4非标记 CAS：4205-91-8中文名称：可乐定 d4 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Alojado ME, et al. The effect of clonidine on the activity of neurons in the rat dorsal raphe nucleus in vitro. Anesth Analg. 1994 Aug;79(2):257-60. [Content Brief]
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CAS:1883545-57-0|Miglustat-d9 hydrochloride，N-Butyldeoxynojirimycin-d9 hydrochloride; NB-DNJ-d9 hydrochloride; OGT 918-d9 hydrochloride
作者：德尔塔生物 日期：2025-06-04
生物活性：Miglustat-d9 (hydrochloride) is the deuterium labeled Miglustat (hydrochloride). Miglustat hydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1)[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Miglustat-d9 hydrochloride 相关抗体:Phospho-Glycogen synthase 1 (S641) AntibodyOGA Antibody (YA2041)分子量：264.79Formula：C10H13D9ClNO4CAS 号：1883545-57-0非标记 CAS：210110-90-0运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (532 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Abian, O., et al., Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase. Mol Pharm, 2011. 8(6): p. 2390-7.;van Giersbergen, P.L. and J. Dingemanse, Influence of food intake on the pharmacokinetics of miglustat, an inhibitor of glucosylceramide synthase. J Cl
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CAS:1188263-47-9|Raloxifene-d4 hydrochloride
作者：德尔塔生物 日期：2025-06-04
生物活性：Raloxifene-d4 (hydrochloride) is the deuterium labeled Raloxifene. Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Raloxifene-d4 hydrochloride 相关抗体:Estrogen Receptor alpha Antibody (YA768)Estrogen Receptor alpha AntibodyGPR30 AntibodyPBR Antibody (YA1785)REA Antibody (YA1848)Estrogen Related Receptor gamma Antibody (YA2009)ERR alpha Antibody (YA2283)Estrogen Receptor beta Antibody (YA1892)14-3-3 Antibody (YA1949)Estrogen Inducible Protein pS2 Antibody (YA2377)MVK Antibody (YA3093)分子量：514.07Formula：C28H24D4ClNO4SCAS 号：1188263-47-9非标记 CAS：84449-90-1运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (533 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-2
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CAS:1346604-90-7|Fingolimod-d4 hydrochloride，FTY720-d4
作者：德尔塔生物 日期：2025-06-04
生物活性：Fingolimod-d4 (hydrochloride) is the deuterium labeled Fingolimod hydrochloride. Fingolimod hydrochloride (FTY720) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride (FTY720) also is a pak1 activator, a immunosuppressant[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fingolimod-d4 hydrochloride 相关抗体:PAK2 Antibody (YA695)PAK1 Antibody (YA1363)KPNA2 Antibody (YA1415)Phospho-PAK1/2/3 (Ser144/Ser141/Ser154) Antibody (YA1530)SCARB1 Antibody (YA1908)EDG3 Antibody (YA2359)Involucrin Antibody (YA2488)JAB1 Antibody (YA3159)Myelin Basic Protein Antibody (YA3271)Phospho-PAK4/5/6 (Ser474/Ser560/Ser602) Antibody (YA3333)S1PR4 AntibodyJMJD6 Antibody (YA1064)Scavenging Receptor SR-BI Antibody (YA1160)EDG1 Antibody (YA1239)LILRB1 Antibody (YA1261)PAK3 Antibody (YA1367)KSR1 Antibody (YA1391)PKN1 Antibody (YA1664)Lipoamide Dehydrogenase Antibody (YA1694)Intra Acrosomal Protein Antibody (YA1856)Lipin 1 Antibody (YA1909)Lactoferrin Antibody (YA2274)LCAT Antibody (YA2864)PKN2 Antibody (YA2890)ITPA Antibody (YA3104)L1CAM Antibody (YA3149)LAT Antibody (YA3161)Myelin Protein Zero Antibody (YA3278)EDG2 Antibody (YA3375)分子量：347.96Formula：C19H
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CAS:1346604-21-4|Ulixacaltamide-d9 hydrochloride，Z944-d9 hydrochloride; PRAX-944-d9 hydrochloride
作者：德尔塔生物 日期：2025-06-04
生物活性：Ulixacaltamide-d9 (hydrochloride) salt is the deuterium labeled Ulixacaltamide hydrochloride[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ulixacaltamide-d9 hydrochloride 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCardiac Troponin I/TNNC1 AntibodySCGN Antibody (YA1167)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)CRCP Antibody (YA3350)Annexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)CAB39 Antibody (YA2761)CUG BP1 Antibody (YA2806)C10orf63 Antibody (YA2894)ITPK1 Antibody (YA3125)ORAI3 Antibody (YA3128)ORAI1 Antibody (YA3157)CREB Regulated Transcription Coactivator 2 Antibody (YA3279)分子量：429.40Formula：C19H19D9Cl2FN3O2CAS 号：1346604-21-4非标记 CAS：1199236-64-0运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of A
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CAS:1189693-23-9|Oxyphenbutazone-d9，羟布宗 d9
作者：德尔塔生物 日期：2025-06-04
生物活性：Oxyphenbutazone-d9 is the deuterium labeled Oxyphenbutazone (HY-B1355A). Oxyphenbutazone is a phenylbutazone derivative, with anti-inflammatory effect. Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is the metabolite of Phenylbutazone.html" class="link-product" target="_blank">Phenylbutazone (HY-B0230). Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis[1][2][3].IC50 & Target：COX, Bacteria[2][3]体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Oxyphenbutazone-d9 相关抗体:COX2 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCOX IV Antibody (YA867)MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：333.43Formula：C19H11D9N2O3CAS 号：1189693-23-9非标记 CAS：129-20-4
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CAS:1189986-72-8|Diphenhydramine-d6 hydrochloride，盐酸苯海拉明 d6 (盐酸盐
作者：德尔塔生物 日期：2025-06-04
生物活性：Diphenhydramine-d6 (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].IC50 & Target：H1 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Diphenhydramine-d6 hydrochloride 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyADGRE1 (F4/80) Antibody (YA002)TSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 Antibody分子量：297.85Formula：C17H16D6ClNOCAS 号：1189986-72-8非标记 CAS：147-24-0性状：固体颜色：White to off-white中文名称：盐酸苯海拉明 d6 (盐酸盐)运输条件：Room temperature in continental
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CAS:1020719-55-4|Paliperidone-d4，帕潘立酮 d4
作者：德尔塔生物 日期：2025-06-04
生物活性：Paliperidone-d4 is the deuterium labeled Paliperidone. Paliperidone (9-Hydroxyrisperidone), the major active metabolite of Risperidone, is a dopamine D2 antagonist and 5-HT2A antagonist. Paliperidone is also active as an antagonist at α1 and α2 adrenergic receptors and H1-histaminergic receptors. Paliperidone, a antipsychotic agent, shows efficacy against schizophrenia[1].IC50 & Target：D2 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Paliperidone-d4 相关抗体:ADRB2 AntibodyDRD2 AntibodyMTNR1A AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Salbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：430.51Formula：C23H23D4FN4O3CAS 号：1020719-55-4非标记 CAS：144598-75-4性状：固体颜色：White to off-white中文名称：帕潘立酮 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (539 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitu
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CAS:2673270-26-1|Montelukast-d6 sodium，MK0476-d6
作者：德尔塔生物 日期：2025-06-04
生物活性：Montelukast-d6 (sodium) is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage[1].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Montelukast-d6 sodium 相关抗体:Leukotriene A4 Hydrolase Antibody (YA2400)分子量：614.20Formula：C35H29D6ClNNaO3SCAS 号：2673270-26-1非标记 CAS：151767-02-1性状：固体颜色：White to off-white中文名称：孟鲁司特钠 d6 (钠盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度： ≥96.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Pu S, et, al. Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury. Front Pharmacol. 2019 Sep 18; 10:1070.;William RHJ, et, al. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am J Respir Crit Care Med. 2002 Jan 1; 165(1): 108-16. [Content Brief]
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CAS:2006272-96-2|β-Caryophyllene-d2，β-石竹烯-d2
作者：德尔塔生物 日期：2025-06-04
生物活性：β-Caryophyllene-d2 is deuterium labeled β-Caryophyllene. β-Caryophyllene is a CB2 receptor agonist.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.β-Caryophyllene-d2 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：206.36Formula：C15H22D2CAS 号：2006272-96-2非标记 CAS：87-44-5性状：油状物颜色：Colorless to light yellow中文名称：β-石竹烯-d2；β-丁香烯-d2运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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CAS:2041095-50-3|Filgotinib-d4，GLPG0634-d4
作者：德尔塔生物 日期：2025-06-04
生物活性：Filgotinib-d4 is the deuterium labeled Filgotinib. Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Filgotinib-d4 相关抗体:Phospho-JAK2 (Tyr1007/1008) AntibodyJAK1 Antibody (YA722)JAK1 AntibodyJAK2 Antibody (YA721)Phospho-JAK2 (Tyr1007+Tyr1008) AntibodyJAK2 Antibody (YA330)Phospho-JNK (Thr183) AntibodyJAK3 Antibody (YA2466)分子量：429.53Formula：C21H19D4N5O3SCAS 号：2041095-50-3非标记 CAS：1206161-97-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Van Rompaey L, et al. Preclinical characterization of GLPG0634, a selective inhibitor of JAK1, for the treatment of inflammatory diseases. J Immunol. 2013, 191(7), 3568-3577. [Content Brief][3]. Menet CJ, et al. Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634. J Med Chem. 2014 Nov 17. [Content Brief]
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CAS:1794810-59-5|Bambuterol-d9 hydrochloride，班布特罗-d9; (±-Bambuterol-d9 hydrochloride; KWD-2183-d9 hydrochloride
作者：德尔塔生物 日期：2025-06-04
生物活性：Bambuterol-d9 (hydrochloride) is the deuterium labeled Bambuterol. Bambuterol ((±)-Bambuterol) hydrochloride is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Bambuterol-d9 hydrochloride 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：412.96Formula：C18H21D9ClN3O5CAS 号：1794810-59-5非标记 CAS：81732-65-2性状：固体颜色：White to off-white中文名称：班布特罗盐酸盐-d9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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CAS:2687960-92-3|Taurodeoxycholate-d6 sodium salt，牛磺脱氧胆酸钠-d6
作者：德尔塔生物 日期：2025-06-04
生物活性：Taurodeoxycholate-d6 sodium salt is a bile salt-related anionic detergent. Taurodeoxycholate-d6 sodium salt is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate-d6 sodium salt is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate-d6 (TDCA) exhibits anti-inflammatory and neuroprotective effects[1][2][3][9][10].体外研究(In Vitro)：Taurodeoxycholate-d6 sodium salt (Taurodeoxycholic acid form) 通过荧光素酶检测，对 CHO 细胞中表达的人 TGR5 具有激动活性，EC50 为 0.79 μM[4]。Taurodeoxycholate-d6 sodium salt (Taurodeoxycholic acid form, 16 h) 对在 HEK293 细胞中表达的野生型和 Y89A 突变型人 TGR5 具有激动剂活性，其 EC50 分别为 0.68 和 8.9 μM (以细胞内 cAMP 水平的升高来评估)[5]。Taurodeoxycholate-d6 sodium salt (Taurodeoxycholic acid form, 50-100 μM，4 h) 增加原代人肝细胞中寡核体 DNA 切割和细胞核凋亡[6]。Taurodeoxycholate-d6 sodium salt (Taurodeoxycholic acid form, 400 μM，18-24 h) 在人肝来源的 Huh7 细胞中增加 DNA 碎片和 PARP 切割，诱导凋亡[7]。Taurodeoxycholate-d6 (0.05-1.00 mM，1-6 天) sodium salt 刺激肠上皮细胞增殖[8]。Taurodeoxycholate-d6 (0.05-1.00 mM，24 h) sodium salt 诱导细胞周期的S期浓度显著增加和 G1 期浓度显著降低，增加c-myc IEC-6细胞蛋白和 mRNA 的表达[8]。Taurodeoxycholate-d6 (25-400 ng/mL，稀释四倍，3 h) sodium salt 通过激活 cAMP-PKA 轴，抑制脂多糖激活的骨髓源性巨噬细胞 (BMDMs) 中 NF-κB 的活化[9]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Taurodeoxycholate-d6 sodium salt 相关抗体:BNSP AntibodyFACL4 AntibodyB
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