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Vincristine-d3-ester sulfate，Leurocristine-d3-ester sulfate; NSC-67574-d3-ester sulfate; 22-Oxovincaleukoblastine-d3-ester sulfate「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-06-05
生物活性：Vincristine-d3-ester (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Vincristine-d3-ester sulfate 相关抗体:ERK1/2 Antibodyalpha Tubulin AntibodyLC3A/B AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyBeta Tubulin Antibodyc-Myc AntibodyCyclin E1 Antibodybeta Tubulin Antibody (YA839)AIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)Doublecortin AntibodyDR5 AntibodyDrosha Antibody分子量：926.05Formula：C46H55D3N4O14SCAS 号：1217854-24-4非标记 CAS：2068-78-2性状：固体颜色：White to off-white中文名称：硫酸长春新碱 ester (硫酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, protect fr
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Sertindole-d4，舍吲哚 d4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-06-05
生物活性：Sertindole-d4 is the deuterium labeled Sertindole. Sertindole, a neuroleptic, is one of the newer antipsychotic medications available[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Sertindole-d4 相关抗体:ADRB2 AntibodyDRD2 AntibodyMTNR1A AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Salbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：444.97Formula：C24H22D4ClFN4OCAS 号：1794737-42-0非标记 CAS：106516-24-9性状：固体颜色：White to off-white中文名称：舍吲哚 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Desmethyl Naproxen-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-06-05
生物活性：Desmethyl Naproxen-d3 is deuterium labeled Desmethyl Naproxen. Desmethyl Naproxen is the metabolite of anti-inflammatory agent Naproxen[1].分子量：219.25Formula：C13H9D3O3CAS 号：1189427-82-4非标记 CAS：23981-47-7性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： ≥98.0%参考文献[1]. Kauffmann RE, Bolliger RO, Wan SH, Oren J. Pharmacokinetics and metabolism of naproxen in children. Dev Pharmacol Ther. 1982;5(3-4):143-150. [Content Brief]
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Tizoxanide-d4，替唑尼特 d4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-06-05
生物活性：Tizoxanide-d4 is the deuterium labeled Tizoxanide. Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Tizoxanide-d4 相关抗体:CD4 AntibodyMRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)TARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)SV40 T Antigen Antibody (YA3256)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)CLEC12A Antibody (YA1419)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)Tat SF1 Antibody (YA2886)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：269.27Formula：C10H3D4N3O4SCAS 号：1246817-56-0非标记 CAS：173903-47-4性状：固体颜色：White to off-white中文名称：替唑尼特 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture and light*In solvent : -80°
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(S-Viloxazine-d5 hydrochloride「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-06-05
生物活性：(S)-Viloxazine-d5 (hydrochloride) is the deuterium labeled (S)-Viloxazine hydrochloride[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：278.79Formula：C13H15D5ClNO3CAS 号：1246816-39-6非标记 CAS：56287-61-7性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Simvastatin-d3，MK 733-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-06-05
生物活性：Simvastatin-d3 is the deuterium labeled Simvastatin[1]. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Simvastatin-d3 相关抗体:HMGCS2 AntibodyERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase Antibody分子量：421.58Formula：C25H35D3O5CAS 号：1002347-61-6非标记 CAS：79902-63-9中文名称：辛伐他汀-d3；辛伐他丁-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharma
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Felbamate-d4，非尔氨酯 d4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-06-05
生物活性：Felbamate-d4 (W-554-d4) is the deuterium labeled Felbamate. Felbamate (W-554) is a potent anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA).IC50 & Target：NMDA Receptor体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Felbamate-d4 相关抗体:PSD95 AntibodyNMDAR1 AntibodyNMDAR2A AntibodyIonotropic Glutamate Receptor 2 Antibody (YA1143)GRM5 Antibody (YA1509)Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845) Antibody (YA2081)NR2E1 Antibody (YA2648)NR2F2 Antibody (YA1223)KA1 Antibody (YA1879)GRIK2 Antibody (YA2705)PSD93 Antibody (YA3187)分子量：242.26Formula：C11H10D4N2O4CAS 号：106817-52-1非标记 CAS：25451-15-4性状：固体颜色：White to off-white中文名称：非尔氨酯 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Ketotifen-d3 fumarate，富马酸酮替芬 d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-06-05
生物活性：Ketotifen-d3 (fumarate) is the deuterium labeled Ketotifen fumarate. Ketotifen (HC 20511) fumarate is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, which is used to prevent asthma attacks[1][2].IC50 & Target：H1 Receptor体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ketotifen-d3 fumarate 相关抗体:ADGRE1 (F4/80) Antibody (YA002)ADGRE1 (F4/80) Antibody (YA920)Poliovirus Receptor Antibody (YA2556)分子量：428.52Formula：C23H20D3NO5SCAS 号：1795138-23-6非标记 CAS：2197125-53-2性状：固体颜色：White to off-white中文名称：富马酸酮替芬 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Eltrombopag-13C4，SB-497115-13C4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-06-05
生物活性：Eltrombopag-13C4 (SB-497115-13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells[1][2][3][4][5].IC50 & Target：Thrombopoietin Receptor, Staphylococcus aureus, Apoptosis[1][3][5]分子量：446.44Formula：C2113C4H22N4O4CAS 号：1217230-31-3非标记 CAS：496775-61-2性状：固体颜色：Light yellow to orange中文名称：艾曲波帕 13C4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Gefitinib-d8，ZD1839-d8「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-06-05
生物活性：Gefitinib-d8 is a deuterium labeled Gefitinib. Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells[1][2].IC50 & Target：IC50: 37 nM (Tyr1173 site, in NR6wtEGFR cells), 37 nM (Tyr992 site, in NR6wtEGFR cells)[1]分子量：454.95Formula：C22H16D8ClFN4O3CAS 号：857091-32-8非标记 CAS：184475-35-2性状：固体颜色：White to off-white中文名称：吉非替尼 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:2933758-47-3|Avobenzone-13C,d3，阿伏苯宗-13C,d3
作者：德尔塔生物 日期：2025-06-05
生物活性：Avobenzone-13C,d3 is the 13C- and deuterium labeled Avobenzone. Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[40].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Avobenzone-13C,d3 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量：314.40Formula：C1913CH19D3O3CAS 号：2933758-47-3非标记 CAS：70356-09-1中文名称：阿伏苯宗-13C,d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditi
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CAS:959119-26-7|Erythromycin-d3，红霉素-d3
作者：德尔塔生物 日期：2025-06-05
生物活性：Erythromycin-d3 is the deuterium labeled Erythromycin[1]. Erythromycin is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research[2][3][4][5].IC50 & Target：Macrolide体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Erythromycin-d3 相关抗体:Ctip2 AntibodyRb AntibodyPhospho-Rb (Ser807) AntibodyRPA32 Antibody (YA679)CDT1 AntibodyDNA-PKcs/PRKDC AntibodyHes1 AntibodyJunB AntibodyLIN28A AntibodyLin28B AntibodyMCM2 AntibodyNanog AntibodyNucleolin AntibodyPCNA AntibodyPDX1 AntibodyRbBP5 AntibodyS100A4 AntibodySP1 AntibodyBRCA1 Antibody (YA819)Argonaute 2 AntibodyBRCA1 AntibodyElongation Factor 1A1 AntibodyKAP1 AntibodyMCM2 Antibody (YA705)MLH1 Antibody (YA703)RNA Polymerase II Subunit B1 AntibodyRPA70 Antibody (YA678)MRP2 AntibodySP7/Osterix AntibodyDNA PKcs Antibody (YA957)分子量：736.95Formula：C37H64D3NO13CAS 号：959119-26-7非标记 CAS：114
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CAS:1356354-25-0|Nafcillin-d5 sodium，萘夫西林钠-d5
作者：德尔塔生物 日期：2025-06-05
生物活性：Nafcillin-d5 (sodium) is the deuterium labeled Nafcillin sodium. Nafcillin sodium, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium can be used for the research of staphylococcal infections[1][2].IC50 & Target：β-lactam体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：441.49Formula：C21H16D5N2NaO5SCAS 号：1356354-25-0非标记 CAS：985-16-0中文名称：萘夫西林钠-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Tan AK, et, al. Identification of the site of covalent attachment of nafcillin, a reversible suicide inhibitor of beta-lactamase. Biochem J. 1992 Jan 1;281 ( Pt 1)(Pt 1):191-6. [Content Brief][3]. Palmer DL, et, al. Bacterial wound colonization after broad-spectrum versus narrow-spectrum antibiotics. Ann Thorac Surg. 1995 Mar;59(3):626-31. [Content Brief][4]. Lawrence I. Mortin, et al. Rapid Bactericidal Activity of Daptomycin agai
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CAS:2733145-07-6|Sarafloxacin-d8 hydrochloride，A-56620-d8 hydrochloride
作者：德尔塔生物 日期：2025-06-05
生物活性：Sarafloxacin-d8 (A-56620-d8) hydrochloride is the deuterium labeled Sarafloxacin hydrochloride. Sarafloxacin hydrochloride (A-56620 hydrochloride) is a quinolone antibiotic drug.IC50 & Target：Quinolone体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Sarafloxacin-d8 hydrochloride 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：429.87Formula：C20H10D8ClF2N3O3CAS 号：2733145-07-6非标记 CAS：91296-87-6中文名称：沙拉沙星-d8 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacothe
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CAS:344299-45-2|3,4,5-Trimethoxyphenylacetic acid-d2
作者：德尔塔生物 日期：2025-06-05
生物活性：3,4,5-Trimethoxyphenylacetic acid-d2 is the deuterium labeled 3,4,5-Trimethoxyphenylacetic acid[1]. 3,4,5-Trimethoxyphenylacetic acid is a metabolite of Mescaline[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.3,4,5-Trimethoxyphenylacetic acid-d2 相关抗体:FMO3 Antibody (YA1992)分子量：228.24Formula：C11H12D2O5CAS 号：344299-45-2非标记 CAS：951-82-6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Demisch L, et al. 3,4,5-Trimethoxybenzoic acid, a new mescaline metabolite in humans. Drug Metab Dispos. 1978 Sep-Oct;6(5):507-9. [Content Brief]
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