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Valganciclovir-d5 TFA,缬更昔洛韦-d5「同位素标记抑制剂」

Valganciclovir-d5 TFA,缬更昔洛韦-d5「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-18

生物活性:Valganciclovir-d5 (TFA) is the deuterium labeled Valganciclovir TFA[1]. Valganciclovir, the L-valyl ester of ganciclovir, is actually a proagent for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections[2][3][4].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:473.42Formula:C16H18D5F3N6O7CAS 号:1402924-31-5非标记 CAS:175865-60-8中文名称:缬更昔洛韦-d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Sugawara M, et al. Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2. J Pharm Sci. 2000 Jun;89(6):781-9. [Content Brief][3]. Chawla JS, et al. Oral valganciclovir versus ganciclovir as delayed pre-emptive therapy for patients after allogeneic hematopoietic stem cell transplant: a pilot trial (04-0274) and review of the literature. Transpl Infect Dis. 2012 Jun14(3):259-67. [

4-Phenylbutyric acid-d5,4-PBA-d5; Benzenebutyric acid-d5「同位素标记抑制剂」

4-Phenylbutyric acid-d5,4-PBA-d5; Benzenebutyric acid-d5「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-18

生物活性:4-Phenylbutyric acid-d5 is the deuterium labeled 4-Phenylbutyric acid[1]. 4-Phenylbutyric acid (4-PBA) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research[2][3][4].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.4-Phenylbutyric acid-d5 相关抗体:S100A10 Antibody (YA675)HDAC1 AntibodyHDAC6 AntibodyHDAC4 Antibody (YA741)SATB2 AntibodyHDAC10 AntibodyHDAC2 AntibodyHDAC3 AntibodyHDAC4 AntibodyHDAC2 Antibody (YA742)SNAI1 AntibodyHDAC11 Antibody (YA2884)HDAC9 Antibody (YA2967)HDAC8 Antibody (YA2994)HDAC6 Antibody (YA740)SATB1 Antibody (YA1154)HDAC7 Antibody (YA3146)分子量:169.23Formula:C10H7D5O2CAS 号:64138-52-9非标记 CAS:1821-12-1中文名称:4-苯基丁酸-d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Chang TH, et al. Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome prolife

Clopidogrel-d3 hydrogen sulfate,(S-(+-Clopidogrel bisulfate-d3; (S-(+-Clopidogrel-d3 hydrogen sulfate「同位素标记抑制剂」

Clopidogrel-d3 hydrogen sulfate,(S-(+-Clopidogrel bisulfate-d3; (S-(+-Clopidogrel-d3 hydrogen sulfate「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-18

生物活性:Clopidogrel-d3 (hydrogen sulfate) is the deuterium labeled Clopidogrel hydrogen sulfate[1]. Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively. Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation.Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor[2][3][4][5][6].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Clopidogrel-d3 hydrogen sulfate 相关抗体:Cytochrome C AntibodyCytochrome P450 17A1 AntibodyAromatase AntibodyCYP11A1 AntibodyCytochrome P450 1B1 Antibody (YA1836)Adrenodoxin Antibody (YA2005)Cytochrome P450 27A1 Antibody (YA2163)Cytochrome P450 2C9 Antibody (YA2166)Cytochrome P450 2E1 Antibody (YA2302)Cytochrome P450 Reductase Antibody (YA2619)Thromboxane A Synthase Antibody (YA2670)P2Y12 Antibody (YA3135)Cytochrome P450 3A4 Antibody (YA3365)HSD11B1 Antibody (YA3376)Cytochrome P450 17A1 Antibody (YA786)CYP2E1 AntibodyCYP1A2 AntibodyPLSCR3 Antibody (YA1672)P2Y6 Antibody (YA1691)PROX1 Antibody (YA1754)Cytochrome P450 4A Antibody (YA2087)Cytochrome P450 24A1 Antibody (YA2121)Cytochrome P4

Ondansetron-d6 hydrochloride,盐酸昂丹司琼-d6; GR 38032-d6 hydrochloride; SN 307-d6 hydrochloride「同位素标记抑制剂」

Ondansetron-d6 hydrochloride,盐酸昂丹司琼-d6; GR 38032-d6 hydrochloride; SN 307-d6 hydrochloride「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-18

生物活性:Ondansetron-d6 (hydrochloride) is the deuterium labeled Ondansetron hydrochloride[1]. Ondansetron hydrochloride is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy[2][3][4][5][6][7].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ondansetron-d6 hydrochloride 相关抗体:MTNR1A Antibody分子量:335.86Formula:C18H14D6ClN3OCAS 号:1225442-22-7非标记 CAS:99614-01-4中文名称:盐酸昂丹司琼-d6; 盐酸枢复宁-d6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Brown AM, et al. Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A). J Physiol. 1998 Mar 15;507 ( Pt 3):653-65. [Content Brief][3]. Barann M, et al. Recombinant human 5-HT3A receptors in outside-out patches of HEK 293 cells: basic properties and barbiturate effects. Naunyn Schmiedebergs Arch Pharmacol. 2000

Guanfacine-13C,15N3,胍法辛-13C,15N3「同位素标记抑制剂」

Guanfacine-13C,15N3,胍法辛-13C,15N3「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-18

生物活性:Guanfacine-13C,15N3 is the 13C and 15N labeled Guanfacine[1]. Guanfacine is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD)[2][3][4].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Guanfacine-13C,15N3 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量:250.07Formula:C813CH9Cl215N3OCAS 号:1189924-28-4非标记 CAS:29110-47-2中文名称:胍法辛-13C,15N3; 氯苯乙胍-13C,15N3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (534 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Amy F T Arnsten, et al. Guanfacine for the treatment of cognitive disorders: a ce

4,4'-Dihydroxybiphenyl-d8「同位素标记抑制剂」

4,4'-Dihydroxybiphenyl-d8「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-17

生物活性:4,4'-Dihydroxybiphenyl-d8 is the deuterium labeled 4,4'-Dihydroxybiphenyl[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:194.26Formula:C12H2D8O2CAS 号:612480-60-1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (522 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

2-Oxopropanoate-13C5 sodium,2-氧代丙酸钠-13C2「同位素标记抑制剂」

2-Oxopropanoate-13C5 sodium,2-氧代丙酸钠-13C2「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-17

生物活性:2-Oxopropanoate-13C5 (sodium) is the 13C labeled Sodium 2-oxopropanoate[1]. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.2-Oxopropanoate-13C5 sodium 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Catalase Antibody (YA552)Catalase Antibody (YA811)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)分子量:112.03Formula:C13C2H3NaO3CAS 号:89196-78-1中文名称:2-氧代丙酸钠-13C2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in

Ethyl methanesulfonate-d5「同位素标记抑制剂」

Ethyl methanesulfonate-d5「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-17

生物活性:Ethyl methanesulfonate-d5 is the deuterium labeled Ethyl methanesulfonate[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:129.19Formula:C3H3D5O3SCAS 号:1219795-44-4性状:液体颜色:Colorless to light yellow运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Pure form-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 99.48%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

1,4-Dimethoxybenzene-d10「同位素标记抑制剂」

1,4-Dimethoxybenzene-d10「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-17

生物活性:1,4-Dimethoxybenzene-d10 is the deuterium labeled 1,4-Dimethoxybenzene[1]. 1,4-Dimethoxybenzene is an endogenous metabolite.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.1,4-Dimethoxybenzene-d10 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:148.23Formula:C8D10O2CAS 号:74079-00-8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (522 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother

Suberic acid-d12,Octanedioic acid-d12「同位素标记抑制剂」

Suberic acid-d12,Octanedioic acid-d12「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-17

生物活性:Suberic acid-d12 is the deuterium labeled Suberic acid[1]. Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Suberic acid-d12 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:186.27Formula:C8H2D12O4CAS 号:169397-99-3性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 98.60%参考文献[1]. Russak EM, et al. Impact of Deuter

4-(Trifluoromethylbenzoic acid-13C6「同位素标记抑制剂」

4-(Trifluoromethylbenzoic acid-13C6「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-17

生物活性:4-(Trifluoromethyl)benzoic acid-13C6 is the 13C labeled 4-(Trifluoromethyl)benzoic acid[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:196.08Formula:C213C6H5F3O2CAS 号:2731552-41-1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

4-Bromobenzaldehyde-13C6「同位素标记抑制剂」

4-Bromobenzaldehyde-13C6「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-17

生物活性:4-Bromobenzaldehyde-13C6 is the 13C labeled 4-Bromobenzaldehyde[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:190.97Formula:C13C6H5BrOCAS 号:1037620-59-9非标记 CAS:1122-91-4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

1,3-Diphenylurea-d10,sym-Diphenylurea-d10「同位素标记抑制剂」

1,3-Diphenylurea-d10,sym-Diphenylurea-d10「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-17

生物活性:1,3-Diphenylurea-d10 is the deuterium labeled 1,3-Diphenylurea[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:222.31Formula:C13H2D10N2OCAS 号:108009-46-7非标记 CAS:102-07-8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Carbamazepine 10,11-epoxide-13C,d2「同位素标记抑制剂」

Carbamazepine 10,11-epoxide-13C,d2「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-17

生物活性:Carbamazepine 10,11-epoxide-13C,d2 is the deuterium labeled Carbamazepine 10,11-epoxide-C13. Carbamazepine 10,11-epoxide-C13 is a 13C-labled Carbamazepine 10,11-epoxide. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Carbamazepine 10,11-epoxide-13C,d2 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:255.27Formula:C1413CH10D2N2O2CAS 号:1189497-48-0运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store

Thiorphan-d7「同位素标记抑制剂」

Thiorphan-d7「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-09-17

生物活性:Thiorphan-d7 is the deuterium labeled Thiorphan[1]. Thiorphan is a selective NEP (neprilysin) inhibitor with an IC50 of 6.9 nM[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:260.36Formula:C12H8D7NO3SCAS 号:1276297-68-7非标记 CAS:76721-89-6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Whyteside AR, Turner AJ. Human neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences. FEBS Lett. 2008 Jul 9;582(16):2382-6. [Content Brief]