CAS号:152881-18-0|KF 17837S
【产品介绍】:
中文别名 KF 17837S 英文别名 KF 17837S; KF17837S; KF-17837S. CAS号 152881-18-0 SMILES O=C(N1CCC)N(CCC)C2=C(N(C)C(C3=CC=C(OC)C(OC)=C3)=N2)C1=O Inchi InChI=1S/C20H26N4O4/c1-6-10-23-18-16(19(25)24(11-7-2)20(23)26)22(3)17(21-18)13-8-9-14(27-4)15(12-13)28-5/h8-9,12H,6-7,10-11H2,1-5H3 InchiKey FSUNYKAEJIVAHY-UHFFFAOYSA-N 分子式 Formula C20H26N4O4 分子量 Molecular Weight 386.45 闪点 FP 熔点 Melting point 沸点 Boiling point Polarizability极化度 密度 Density 蒸汽压 Vapor Pressure 溶解度Solubility 性状 Solid powder 储藏条件 Storage conditions Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). 产品说明 KF 17837S(CAS:152881-18-0):仅限应用于工业或者科学研究过程中非医疗目的,不应用于人类或动物的临床诊断以及治过程疗,该产品非药用,非食用。 IntroductionKF 17837S is an adenosine A(2a) receptor antagonists, which is potential therapeutic and neuroprotective effects in Parkinson's disease. Application1 Application2 Application3 警示图 危险性 Warning 危险性警示 安全声明 安全防护 备注 [1]Morelli M, Wardas J. Adenosine A(2a) receptor antagonists: potential therapeutic and neuroprotective effects in Parkinson's disease. Neurotox Res. 2001 Nov;3(6):545-56. PubMed PMID: 15111244. [2]Correa M, Wisniecki A, Betz A, Dobson DR, O'Neill MF, O'Neill MJ, Salamone JD. The adenosine A2A antagonist KF17837 reverses the locomotor suppression and tremulous jaw movements induced by haloperidol in rats: possible relevance to parkinsonism. Behav Brain Res. 2004 Jan 5;148(1-2):47-54. PubMed PMID: 14684247. [3] Bivalacqua TJ, Champion HC, Lambert DG, Kadowitz PJ. Vasodilator responses to adenosine and hyperemia are mediated by A(1) and A(2) receptors in the cat vascular bed. Am J Physiol Regul Integr Comp Physiol. 2002 Jun;282(6):R1696-709. PubMed PMID: 12010752. 对不起,暂无产品评价!




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