【产品介绍】：

中文别名 Methyl 4-(3-acetyl-4-hydroxy-1-(2-(2-methyl-1H-indol-3-yl)ethyl)-5-oxo-2,5-dihydro-1H-pyrrol-2-yl)benzoate 英文别名 PYD-106; PYD 106; PYD106. CAS号 1560894-05-4 SMILES O=C(OC)C1=CC=C(C(C(C(C)=O)=C2O)N(CCC3=C(C)NC4=C3C=CC=C4)C2=O)C=C1 Inchi InChI=1S/C25H24N2O5/c1-14-18(19-6-4-5-7-20(19)26-14)12-13-27-22(21(15(2)28)23(29)24(27)30)16-8-10-17(11-9-16)25(31)32-3/h4-11,22,26,29H,12-13H2,1-3H3 InchiKey LIFGURQFZLMSDE-UHFFFAOYSA-N 分子式 Formula C25H24N2O5 分子量 Molecular Weight 432.476 闪点 FP 熔点 Melting point 沸点 Boiling point Polarizability极化度 密度 Density 蒸汽压 Vapor Pressure 溶解度Solubility 性状 Solid powder 储藏条件 Storage conditions Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). 产品说明 PYD-106(CAS:1560894-05-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。 IntroductionPYD-106 is a GluN2C-selective NMDA Receptor Positive Allosteric Modulator. Application1 Application2 Application3 警示图 危险性 Warning 危险性警示 安全声明 安全防护 备注 [1]Kaiser TM, Kell SA, Kusumoto H, Shaulsky G, Bhattacharya S, Epplin MP, StrongKL, Miller EJ, Cox BD, Menaldino DS, Liotta DC, Traynelis SF, Burger PB. TheBioactive Protein-Ligand Conformation of GluN2C-Selective Positive AllostericModulators Bound to the NMDA Receptor. Mol Pharmacol. 2018 Feb;93(2):141-156.doi: 10.1124/mol.117.110940. Epub 2017 Dec 14. PubMed PMID: 29242355; PubMedCentral PMCID: PMC5767683. [2]Hackos DH, Hanson JE. Diverse modes of NMDA receptor positive allostericmodulation: Mechanisms and consequences. Neuropharmacology. 2017 Jan;112(PtA):34-45. doi: 10.1016/j.neuropharm.2016.07.037. Epub 2016 Jul 30. Review. PubMedPMID: 27484578. [3] Khatri A, Burger PB, Swanger SA, Hansen KB, Zimmerman S, Karakas E, Liotta DC,Furukawa H, Snyder JP, Traynelis SF. Structural determinants and mechanism ofaction of a GluN2C-selective NMDA receptor positive allosteric modulator. MolPharmacol. 2014 Nov;86(5):548-60. doi: 10.1124/mol.114.094516. Epub 2014 Sep 9.PubMed PMID: 25205677; PubMed Central PMCID: PMC4201136. 对不起，暂无产品评价！