CAS号:65934-61-4|RU 24926
【产品介绍】:
中文别名 3,3'-((propylazanediyl)bis(ethane-2,1-diyl))diphenol 英文别名 RU 24926; RU24926; RU-24926; CAS号 65934-61-4 SMILES CCCN(CCC1=CC(O)=CC=C1)CCC2=CC(O)=CC=C2 Inchi InChI=1S/C19H25NO2/c1-2-11-20(12-9-16-5-3-7-18(21)14-16)13-10-17-6-4-8-19(22)15-17/h3-8,14-15,21-22H,2,9-13H2,1H3 InchiKey RVXNTMVFBHOIKH-UHFFFAOYSA-N 分子式 Formula C19H25NO2 分子量 Molecular Weight 299.41 闪点 FP 熔点 Melting point 沸点 Boiling point Polarizability极化度 密度 Density 蒸汽压 Vapor Pressure 溶解度Solubility 性状 Solid powder 储藏条件 Storage conditions Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). 产品说明 RU 24926(CAS:65934-61-4):仅限应用于工业或者科学研究过程中非医疗目的,不应用于人类或动物的临床诊断以及治过程疗,该产品非药用,非食用。 IntroductionRU 24926 is a di-(phenethyl)-amine derivative that acts as a dopamine-D2 receptor agonist. Application1 Application2 Application3 警示图 危险性 Warning 危险性警示 安全声明 安全防护 备注 [1]Dean B, Srikanthan P, Copolov DL. Inhibition of [3H]dopamine uptake by platelets by the dopamine-D2 receptor agonist RU 24926. J Pharm Pharmacol. 1991 Jan;43(1):56-7. PubMed PMID: 1676063. [2]Fortin M, Degryse M, Petit F, Hunt PF. The dopamine D2 agonists RU 24213 and RU 24926 are also kappa-opioid receptor antagonists. Neuropharmacology. 1991 Apr;30(4):409-12. PubMed PMID: 1677169. [3] Suaudeau C, Costentin J. Analgesic effect of the direct D2 dopamine receptor agonist RU 24926 and cross tolerance with morphine. Fundam Clin Pharmacol. 1995;9(2):147-52. PubMed PMID: 7628827. [4] Simon P, Charpentier S, Costentin J. An automated method for the assessment of spontaneous and stereotyped climbing behavior in mice. Effects of the selective D1- and D2-dopamine receptor agonists SKF-38393 and RU-24926 and their association. Methods Find Exp Clin Pharmacol. 1991 Mar;13(2):99-104. PubMed PMID: 1830125. [5] Johnson EA, Tsai CE, Lucci J, Harrison-Shahan Y, Azzaro AJ. Dopamine D2 synthesis-modulating receptors are present in the striatum of the guinea pig. Neuropharmacology. 1992 Jan;31(1):95-101. PubMed PMID: 1347405. 6: Conzelmann U, Holland A, Meyer DK. Effects of selective dopamine D2-receptor agonists on the release of cholecystokinin-like immunoreactivity from rat neostriatum. Eur J Pharmacol. 1984 May 18;101(1-2):119-25. PubMed PMID: 6235119.7: Vasse M, Protais P. Potentiation of apomorphine-induced stereotyped behaviour by acute treatment with dopamine depleting agents: a potential role for an increased stimulation of D1 dopamine receptors. Neuropharmacology. 1989 Sep;28(9):931-9. PubMed PMID: 2554186.8: Suaudeau C, Dourmap N, Costentin J. Rapid and long lasting reduction of the hypothermic effect of a D2 dopamine agonist after an intracerebroventricular injection of 6-hydroxydopamine. Neuropharmacology. 1995 Jan;34(1):101-5. PubMed PMID: 7623958.9: Sokoloff P, Riou JF, Martres MP, Schwartz JC. Presence of dopamine D-2 receptors in human tumoral cell lines. Biochem Biophys Res Commun. 1989 Jul 31;162(2):575-82. PubMed PMID: 2527031.10: Yarbrough GG, McGuffin-Clineschmidt J, Singh DK, Haubrich DR, Bendesky RJ, Martin GE. Electrophysiological, biochemical and behavioral assessment of dopamine autoreceptor activation by a series of dopamine agonists. Eur J Pharmacol. 1984 Mar 16;99(1):73-8. PubMed PMID: 6723791.1 对不起,暂无产品评价!