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中文别名 Cefprozil 英文别名 Cefprozil; Cefprozil anhydrous; Brisoral; Cefzil; Cefprozilo; Cefprozilum; Procef; cefprozil monohydrate; Arzimol; BMY 28100; BMY-28100; Brisoral; CAS号 92665-29-7 SMILES C/C=C/C1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)SC1)C(=O)O Inchi InChI=1S/C18H19N3O5S/c1-2-3-10-8-27-17-13(16(24)21(17)14(10)18(25)26)20-15(23)12(19)9-4-6-11(22)7-5-9/h2-7,12-13,17,22H,8,19H2,1H3,(H,20,23)(H,25,26)/b3-2+/t12-,13-,17-/m1/s1 InchiKey WDLWHQDACQUCJR-ZAMMOSSLSA-N 分子式 Formula C18H19N3O5S 分子量 Molecular Weight 389.43 闪点 FP 熔点 Melting point 沸点 Boiling point Polarizability极化度 密度 Density 蒸汽压 Vapor Pressure 溶解度Solubility 性状 Solid powder 储藏条件 Storage conditions Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). 产品说明 Cefprozil(CAS:92665-29-7):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。 IntroductionCefprozil, under the marketed trade name Cefzil, is a second-generation cephalosporin type antibiotic. It can be used to treat bronchitis, ear infections, skin infections, and other bacterial infections. It comes as a tablet and as a liquid suspension. Cefprozil's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefprozil inhibits bacterial septum and cell wall synthesis formation. Application1 Application2 Application3 警示图 危险性 Warning 危险性警示 安全声明 安全防护 备注 [1]Liu M, Ma JY, Zhang Y, Wang X, Zhao H, Du A, Yang M, Meng L, Deng M, Liu H. AnLC-MS/MS method for simultaneous determination of cefprozil diastereomers inhuman plasma and its application for the bioequivalence study of two cefproziltablets in healthy Chinese volunteers. Biomed Chromatogr. 2016 Mar;30(3):288-93.doi: 10.1002/bmc.3547. Epub 2015 Aug 27. PubMed PMID: 26129932. [2]Attia KA, Nassar MW, El-Zeiny MB, Serag A. Stability indicating methods forthe analysis of cefprozil in the presence of its alkaline induced degradationproduct. Spectrochim Acta A Mol Biomol Spectrosc. 2016 Jan 21;159:1-6. doi:10.1016/j.saa.2016.01.026. [Epub ahead of print] PubMed PMID: 26814624. [3] Pistiki A, Tsaganos T, Galani I, Giamarellos-Bourboulis EJ. In Vitro Activityof Oral Cephalosporins (Cefprozil and Cefixime) Against Ciprofloxacin-ResistantEnterobacteriaceae from Community-Acquired Urinary-Tract Infections. Infect DisTher. 2015 Dec;4(4):425-32. doi: 10.1007/s40121-015-0089-3. Epub 2015 Sep 21.PubMed PMID: 26391612; PubMed Central PMCID: PMC4675762. [4] Attia KA, Nassar MW, El-Zeiny MB, Serag A. Different approaches inmanipulating ratio spectra applied for the analysis of Cefprozil in presence ofits alkaline-induced degradation product: a comparative study. Spectrochim Acta AMol Biomol Spectrosc. 2015 Jun 15;14 [5]289-94. doi: 10.1016/j.saa.2015.03.038.Epub 2015 Mar 10. PubMed PMID: 25791886. 5: Hou D, Cao X. Synthesis of two thermo-responsive copolymers forming recyclableaqueous two-phase systems and its application in cefprozil partition. JChromatogr A. 2014 Jul 4;1349:30-6. doi: 10.1016/j.chroma.2014.04.075. Epub 2014Apr 28. PubMed PMID: 24857035. 对不起，暂无产品评价！