CAS号:99260-67-0|Saquayamycin B
【产品介绍】:
中文别名 (3S,4aR,12bR)-9-((2R,4aR,5aS,7R,9S,9aR,10aS)-2,9-dimethyl-3-oxooctahydro-2H,7H-dipyrano[2,3-b4',3'-e][1,4]dioxin-7-yl)-4a,8,12b-trihydroxy-3-methyl-3-(((2R,5S,6S)-6-methyl-5-(((2R,6R)-6-methyl-5-oxo-5,6-dihydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,4,4a,12b-tetrahydrotetraphene-1,7,12(2H)-trione 英文别名 Saquayamycin B; CAS号 99260-67-0 SMILES O=C1C[C@](O[C@@H]2CC[C@H](O[C@H]3C=CC([C@@H](C)O3)=O)[C@H](C)O2)(C)C[C@]4(O)[C@]1(O)C(C(C5=CC=C([C@H]6C[C@]7([H])O[C@@](CC([C@@H](C)O8)=O)([H])[C@@]8([H])O[C@]7([H])[C@H](C)O6)C(O)=C5C9=O)=O)=C9C=C4 Inchi InChI=1S/C43H48O16/c1-18-25(44)8-10-32(53-18)57-27-9-11-33(54-20(27)3)59-41(5)16-31(46)43(51)35-24(12-13-42(43,50)17-41)37(48)34-23(38(35)49)7-6-22(36(34)47)28-15-29-39(21(4)52-28)58-40-30(56-29)14-26(45)19(2)55-40/h6-8,10,12-13,18-21,27-30,32-33,39-40,47,50-51H,9,11,14-17H2,1-5H3/t18-,19-,20+,21+,27+,28-,29+,30-,32+,33-,39-,40-,41-,42+,43-/m1/s1 InchiKey WUQKUPKWGZHYBN-CBRSCIEJSA-N 分子式 Formula C43H48O16 分子量 Molecular Weight 820.84 闪点 FP 熔点 Melting point 沸点 Boiling point Polarizability极化度 密度 Density 蒸汽压 Vapor Pressure 溶解度Solubility 性状 Solid powder 储藏条件 Storage conditions Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). 产品说明 Saquayamycin B(CAS:99260-67-0):仅限应用于工业或者科学研究过程中非医疗目的,不应用于人类或动物的临床诊断以及治过程疗,该产品非药用,非食用。 IntroductionSaquayamycin B is a glycoside of aquayamycin that acts on Gram-positive bacteria and inhibits the growth of adriamycin-sensitive and adriamycin-resistant P388 leukemia cells. Application1 Application2 Application3 警示图 危险性 Warning 危险性警示 安全声明 安全防护 备注 [1]Abdelfattah MS, Kharel MK, Hitron JA, Baig I, Rohr J. Moromycins A and B, isolation and structure elucidation of C-glycosylangucycline-type antibiotics from Streptomyces sp. KY002. J Nat Prod. 2008 Sep;71(9):1569-73. doi: 10.1021/np800281f. Epub 2008 Jul 3[1]PubMed PMID: 18666798; PubMed Central PMCID: PMC2562265. [2]Shaaban KA, Ahmed TA, Leggas M, Rohr J. Saquayamycins G-K, cytotoxic angucyclines from Streptomyces sp. Including two analogues bearing the aminosugar rednose. J Nat Prod. 2012 Jul 27;75(7):1383-92. doi: 10.1021/np300316b. Epub 2012 Jul 3. PubMed PMID: 22758660; PubMed Central PMCID: PMC3412564. [3] Henkel T, Zeeck A. Derivatives of saquayamycins A and B. Regio- and diastereoselective addition of alcohols to the L-aculose moiety. J Antibiot (Tokyo). 1990 Jul;43(7):830-7. PubMed PMID: 2387777. [4] Uchida T, Imoto M, Watanabe Y, Miura K, Dobashi T, Matsuda N, Sawa T, Naganawa H, Hamada M, Takeuchi T. Saquayamycins, new aquayamycin-group antibiotics. J Antibiot (Tokyo). 1985 Sep;38(9):1171-81. PubMed PMID: 3840796. 对不起,暂无产品评价!