【产品介绍】：

产品名称 Elvitegravir(GS-9137,JTK-303) 英文名称 Elvitegravir (GS-9137, JTK-303) 应用 An HIV-1 integrase inhibitor 规格或纯度 ≥99% 别名 埃替拉韦 英文别名 GS-9137; JTK-303; EVG; D06677;6-[(3-chloro-2-fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 运输条件 冰袋运输 生化机理 Elvitegravir is an inhibitor of HIV-1 integrase which is responsible for the strand-transfer step of integration. Studies indicate that Elvitegravir is effective against HIV-1 strains that are resistant to other agents such as nucleotide reverse-transcriptase inhibitors (NRTIs), nonnucleoside reverse-transcriptase inhibitors (NNRTIs), and protease inhibitors (PIs), as a result of Elvitegravir's ability to block the function of HIV1 integrase.Elvitegravir is an inhibitor of HIV integrase. It inhibits HIV integrase from HIV 1 IIIB (IC 50 = 0.7 nM), HIV 2 EHO (IC 50 = 2.8 nM)\xa0and HIV-2 ROD (IC 50 = 1.1 nM) in cell free assays.\xa0Elvitegravir blocks integration of HIV cDNA via inhibition of DCAS编号 697761-98-1 溶解性 DMSO ≥86mg/mL Water <1.2mg/mL Ethanol ≥85mg/mL 储存温度 2-8°C储存 分子量 447.88 分子式 C23H23ClFNO5 PubChem CID 5277135