【产品介绍】：

产品名称 AZD8330 英文名称 AZD8330 应用 An antineoplastic selective MEK inhibitor 规格或纯度 ≥98% 别名 ARRY-424704; ARRY424704;ARRY704; AZD8330 英文别名 AZD-8330; ARRY-704;2-(2-氟-4-碘苯氨基)-N-(2-羟基乙氧基)-1,5-二甲基-6-氧代-1,6-二氢吡啶-3-甲酰胺; 运输条件 超低温冰袋运输 生化机理 AZD8330 potently and strongly inhibits MEK 1/2. AZD8330 has no inhibitory activity against over 200 other kinases including at concentrations up to 10 μM. AZD8330 demonstrates sub-nanomolar potency in mechanistic (pERK) and low to sub-nanomolar potency in functional (proliferation) assays in MEK 1/2 inhibitor sensitive cell lines.A selective allosteric MEK inhibitor. Orally active. IC 50 of 7 nM.CAS编号 869357-68-6 折光率 1.66 溶解性 DMSO 92 mg/mL Water <1 mg/mL Ethanol 92 mg/mL 储存温度 -20°C储存 密度 1.73 分子量 461.23 分子式 C16H17FIN3O4 PubChem CID 16666708