【产品介绍】：

产品名称 NQDI 1 英文名称 NQDI 1 规格或纯度 97% 别名 2,7-二氢-2,7-二氧代-3H-萘并[1,2,3-de]喹啉-1-羧酸乙酯 英文别名 2,7-Dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid ethyl ester; ethyl 2,7-dioxo-3,7-dihydro-2H-naphtho[1,2,3-de]quinoline-1-carboxylate;NQDI-1 运输条件 超低温冰袋运输 生化机理 Selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50= 3μM, Ki= 500 nM).NQDI-1 is an inhibitor of apoptosis signal-regulating kinase (ASK1), Ki = 500 nM. NQDI-1 shows little or no inhibitory activity against Aurora A or ROCK kinases, or several receptor tyrosine kinases. NQDI-1 inhibits the activation of caspase-3 and prevents cell death by apoptosis. It is neuroprotective and prevents the ROS-induced apoptosis of the neurons.CAS编号 175026-96-7 熔点 >270°C 溶解性 Solvent:DMSO, Max Conc. mg/mL: 3.19, Max Conc. mM: 10 储存温度 -20°C储存 分子量 319.31 分子式 C19H13NO4 Smiles O=C2NC1=CC=CC4=C1C(C3=CC=CC=C3C4=O)=C2C(OCC)=O PubChem CID 5522952 InChi Key UFJGFNHRMPMALC-UHFFFAOYSA-N