德尔塔
您当前所在位置:首页 > 生命科学 > 全部产品

CAS:224452-66-8|Retapamulin

发布时间:2022-03-18     作者:德尔塔   分享到:

【产品介绍】:

产品名称 Retapamulin 英文名称 Retapamulin 应用 A broad spectrum antibiotic with no cross resistance to existing classes 规格或纯度 ≥99% 别名 瑞他帕林; 瑞他莫林 生化机理 Retapamulin(SB-275833) is a topical antibiotic developed by GlaxoSmithKline. Retapamulin(SB-275833) is the first drug in the new class of pleuromutilin antibiotics to be approved for human use.Retapamulin(SB-275833) is marketed as an ointment under the brand names Altabax and Altargo. Retapamulin(SB-275833) is useful for Antibiotics.Retapamulin is a semi-synthetic pleuormutilin prepared by reacting pleuromutilin tosylate with tropine-3-thiol to give a more hydrophobic analogue with a tertiary amine. This enables formulation as a stable hydrochloride salt. Retapamulin is a broad spectrum antibiotic with no cross resistance to existing antibiotic classes, and is the first pleuromutilin approved for human use. Like all the pleuromutilins, retapamulin inhibits protein synthesis by binding to domain V of 23S rRNA.CAS编号 224452-66-8 敏感性 比旋光度 折光率 熔点 凝固点 沸点 溶解性 DMSO 104 mg/mL ;Water <1 mg/mL;Ethanol 104 mg/mL 储存温度 储存温度-20°C Reaxys-RN RTECS MDL号 分子量 517.76 FEMA编号 分子式 C30H47NO4S EC号 Smiles PubChem CID 6918462