【产品介绍】：

产品名称 组胺 英文名称 Histamine, Free Base 应用 内源性H1 和 H2 组胺受体激动剂；H1 激活并使Ca2+移动；H2 激活并刺激神经元中腺苷酸环化酶(adenylate cyclase)活性；激活NO合成酶；血管扩张剂。 规格或纯度 96% 别名 2-(4-咪唑基)乙胺 英文别名 2-(4-Imidazolyl)ethylamine;1H-Imidazole-4-ethanamine; Ergotidine 运输条件 超低温冰袋运输 生化机理 Histamine, Free Base is a potent vasodilator found in normal tissues and blood. This compound is formed by the decarboxylation of L-histidine and activates NOS (nitric oxide synthase), resulting in the release of nitric oxide. Activation of Histamine H1 Receptors leads to Ca2+ mobilization; whereas, Histamine H2 Receptor activation stimulates adenylate cyclase activity in neurons. Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation.Potent vasodilator. Formed by the decarboxylation of L-histidine. Acts as an agonist for endogenous histamine receptors. Histamine H 1 receptor activation mobilizes Ca 2+ ; H 2 activation stimulates adenylate cyclase activity in neurons.CAS编号 51-45-6 敏感性 易吸潮,对热和光敏感 熔点 83-84°C 沸点 167°C 溶解性 Soluble in water, alcohol, and hot chloroform. 储存温度 -20°C储存 RTECS MS1050000 MDL号 MFCD00005210 分子量 111.15 分子式 C5H9N3 EC号 200-100-6 PubChem CID 774