【产品介绍】：

产品名称 Dovitinib (TKI-258, CHIR-258) 英文名称 Dovitinib (TKI-258, CHIR-258) 应用 The free base form of an FGFR inhibitor 规格或纯度 ≥99% 别名 CHIR-258;多韦替尼 英文别名 CHIR-258;TKI258;TKI-258;TKI 258;CHIR258;CHIR 258;4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one 运输条件 超低温冰袋运输 生化机理 Dovitinib, Free Base, is the non-salt form of dovitinib, lactate salt (sc-396753). Dovitinib is a multitargeted growth factor receptor kinase inhibitor to VEGFR, FGFR3, PDGFR and c-KIT.Potent, selective inhibitor of class III-V receptor tyrosine kinases (RTKs). Inhibits FLT3 (IC 50 = 1 nM), c-KIT (IC 50 = 2 nM), FGFR (IC 50 = 8 nM), VEGFR1/2/3 (IC 50 values are\xa010 nM, 13 nM and 8 nM respectively)。CAS编号 405169-16-6 溶解性 DMSO:34 mg/mL,Insoluble in water and Ethanol 储存温度 -20°C储存 分子量 392.43 分子式 C21H21FN6O PubChem CID 135398510