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CAS:1035270-39-3|AZD4547

发布时间:2022-03-15     作者:德尔塔   分享到:

【产品介绍】:

产品名称 AZD4547 英文名称 AZD4547 应用 A novel selective FGFR inhibitor targeting FGFR1, FGFR2, and FGFR3. 规格或纯度 ≥99% 别名 AZD 4547;AZD-4547;N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide;rel-N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]benzamide 英文别名 AZD 4547;AZD-4547;N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide;rel-N-[5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]benzamide 运输条件 超低温冰袋运输 生化机理 AZD4547 is a novel selective FGFR inhibitor targeting FGFR1, FGFR2, and FGFR3. AZD4547 treatment potently inhibits FGFR and MAPK phosphorylation in tumor cell lines in a dose-dependent manner.Novel, selective\xa0inhibitor\xa0of the FGFR1, 2, and 3 tyrosine kinases. Binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, thus resulting in the inhibition of tumor cell proliferation and tumor cCAS编号 1035270-39-3 溶解性 DMSO 92 mg/mL (198.45 mM);Water <1 mg/mL (<1 mM);Ethanol <1 mg/mL (<1 mM); 储存温度 -20°C储存 分子量 463.57 分子式 C26H33N5O3 PubChem CID 51039095