【产品介绍】：

产品名称 N-[4-[[3-氯-4-[(3-氟苯基)甲氧基]苯基]氨基]-6-喹唑啉基]-2-丙烯酰胺对甲苯磺酸盐 英文名称 AST-1306 TsOH 应用 A potent and selective inhibitor of EGFR phosphorylation. 规格或纯度 ≥98% 别名 N-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-propenamide 4-methylbenzenesulfonate;AST-1306 (p-Toluenesulfonic acid); AST1306 (p-Toluenesulfonic acid); AST 1306 (p-Toluenesulfonic acid;AST-6 英文别名 N-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-propenamide 4-methylbenzenesulfonate;AST-1306 (p-Toluenesulfonic acid); AST1306 (p-Toluenesulfonic acid); AST 1306 (p-Toluenesulfonic acid;AST-6 运输条件 冰袋运输 生化机理 AST-1306 TsOH is a potent(pM) and selective inhibitor of EGFR and ErbB4 (IC50 = 500pM and 800 pM, respectively). AST 1306 blocks phosphorylation of EGFR and also prevents downstream pathways. AST 1306 also dose-dependently inhibits EGF-induced EGFR phosphorylation in the A549 cancer cell line.CAS编号 1050500-29-2 溶解性 Soluble in DMSO (124 mg/mL), water (<1 mg/mL), and ethanol (<1 mg/mL). 储存温度 2-8°C 分子量 621.08 分子式 C24H18ClFN4O2·C7H8O3S PubChem CID 25027665