【产品介绍】：

产品名称 Masitinib (AB1010) 英文名称 Masitinib (AB1010) 应用 A tyrosine kinase, c-Kit, PDGFR, FGFR3, the FAK pathway inhibitor. 规格或纯度 ≥98% 别名 马赛替尼 生化机理 Masitinib (AB1010) is a tyrosine kinase, c-Kit, PDGFR, FGFR3, the FAK pathway inhibitor with IC50 of 150 ± 80, 200 ± 40 nM for KIT tyrosine phosphorylation and the recombinant wild-type KIT. Masitinib can enhance the antiproliferative effects of gemcitabine (GEM) in pancreatic cancer cells. Masitinib potently inhibits KIT with activating mutations in the juxtamembrane domain.CAS编号 790299-79-5 溶解性 DMSO 00 mg/mL (200.54 mM);Water <1 mg/mL (<1 mM);Ethanol 4 mg/mL (8.02 mM) 储存温度 储存温度-20°C 分子量 498.65 分子式 C28H30N6OS PubChem CID 10074640