【产品介绍】：

产品名称 Apremilast 英文名称 Apremilast 规格或纯度 ≥99% 别名 CC-10004 英文别名 ApreMilast;(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione;(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide;ApreMilast,CC-10004 运输条件 超低温冰袋运输 生化机理 Apremilast, a novel small mol. inhibitor of PDE4. Apremilast has profound anti-inflammatory properties in animal models of inflammatory disease, as well as human chronic inflammatory diseases such as psoriasis and psoriatic arthritis. Apremilast blocks the synthesis of several pro-inflammatory cytokines and chemokines, such as tumor necrosis factor alpha, interleukin 23, CXCL9, and CXCL10 in multiple cell types. As this novel PDE4 inhibitor interferes with several key processes of inflammation, Apremilast may emerge as a promising new drμg for the treatment of chronic inflammatory diseases such as those of the skin and the joints.CAS编号 608141-41-9 溶解性 DMSO 92 mg/mL Water <1 mg/mL Ethanol <1 mg/mL 储存温度 -20°C储存 分子量 460.5 分子式 C22H24N2O7S PubChem CID 11561674