【产品介绍】：

Name:lurasidone
Synonyms:SM-13496
CAS Number:367514-87-2
Formula:C28H36N4O2S
M.w.:492.68
DMSO (mg/mL)Max Solubility:7
DMSO (mM)Max Solubility:14.21
Form:free base
SMILES:O=C1C2C3CCC(C3)C2C(=O)N1CC4CCCCC4CN5CCN(CC5)C6=NSC7=CC=CC=C67
ALogP:4.896
Target:5-HT Receptor,Dopamine Receptor
Pathway:Neuronal Signaling
Information:Lurasidone (SM-13496) is a second-generation antipsychotic agent that exhibits full antagonism at dopamine D2 and serotonin 5-HT2A receptors with binding affinities Ki = 1 nM and Ki = 0.5 nM, respectively. It also has high affinity for serotonin 5-HT7 receptors (Ki = 0.5 nM), partial agonist activity at 5-HT1A receptors (Ki = 6.4 nM) and lacks affinity for histamine H1 and muscarinic M1 receptors.
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