德尔塔
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「同位素标记抑制剂」CAS:326495-37-8|1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13

发布时间:2025-06-13     作者:德尔塔生物   分享到:

【产品介绍】:

生物活性:1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly
体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量:803.23
Formula:C44H75D13NO8P
CAS 号:326495-37-8
性状:固体
颜色:White to off-white
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Powder:-20°C:3 years
In solvent:-80°C:6 months,-20°C:1 month
纯度 & 产品资料
纯度: ≥99.0%
参考文献
[1]. Andrew D Miller. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811.
 [Content Brief]
[2]. Jayesh A Kulkarni, et al. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 21;11(45):21733-21739.
 [Content Brief]
[3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.
 [Content Brief]