【产品介绍】：

生物活性：Ribociclib-d8 is the deuterium labeled Ribociclib[1]. Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[2].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Ribociclib-d8 相关抗体:
Cyclin E1 Antibody (YA483)
CD133 Antibody
Cdk2 Antibody
Cdk4 Antibody
Cdk5 Antibody
Cdk6 Antibody
Cyclin D3 Antibody
Cdk7 Antibody
CDK16 Antibody
CDK5 Antibody (YA796)
CDK9 Antibody
CDKN2A/p16INK4a Antibody (YA508)
Phospho-CDK1 (Tyr15) Antibody
Phospho-CDK1/2/3 (Thr14) Antibody
Phospho-CDK2 (Tyr15) Antibody
Phospho-Cyclin B1 (Ser126) Antibody
CDKN2A/p16INK4a Antibody
CDKN2C Antibody
Phospho-CDC6 (Ser54) Antibody (YA1017)
Cyclin E2 Antibody (YA2594)
CDC25C Antibody (YA2624)
CDC6 Antibody (YA2626)
CDC40 Antibody (YA3168)
Cyclin A1/A2 Antibody (YA3336)
CRK Antibody (YA790)
Cyclin H Antibody (YA788)
Cyclin H Antibody
Phospho-CDC6 (Ser106) Antibody (YA1016)
CDC7 Antibody (YA1152)
Cyclin D3/CCND3 Antibody (YA1201)
分子量：442.59
Formula：C23H22D8N8O
CAS 号：2167898-24-8
非标记 CAS：1211441-98-3
性状：固体
颜色：Off-white to light yellow
中文名称：瑞博西尼-d8；瑞柏司可里布-d8
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month